Model system for live imaging of neuronal responses to injury and repair [0.03%]
用于活体成像神经元损伤和修复反应的模型系统
Mathieu Gravel,Yuan-Cheng Weng,Jasna Kriz
Mathieu Gravel
Although it has been well established that induction of growth-associated protein-43 (GAP-43) during development coincides with axonal outgrowth and early synapse formation, the existence of neuronal plasticity and neurite outgrowth in the ...
Model system for live imaging of neuronal responses to injury and repair [0.03%]
创伤和修复过程中活体神经元反应的模型系统
Mathieu Gravel,Yuan-Cheng Weng,Jasna Kriz
Mathieu Gravel
Although it has been well established that induction of growth-associated protein-43 (GAP-43) during development coincides with axonal outgrowth and early synapse formation, the existence of neuronal plasticity and neurite outgrowth in the ...
Characterization and evaluation of two novel fluorescent sigma-2 receptor ligands as proliferation probes [0.03%]
两种新型荧光σ-2受体配体增殖探针的表征和评价
Chenbo Zeng,Suwanna Vangveravong,Lynne A Jones et al.
Chenbo Zeng et al.
We synthesized and characterized two novel fluorescent sigma-2 receptor selective ligands, SW120 and SW116, and evaluated these ligands as potential probes for imaging cell proliferation. Both ligands are highly selective for sigma-2 recept...
Characterization and evaluation of two novel fluorescent sigma-2 receptor ligands as proliferation probes [0.03%]
两种新型荧光σ-2受体配体的表征及其作为增殖探针的应用评价
Chenbo Zeng,Suwanna Vangveravong,Lynne A Jones et al.
Chenbo Zeng et al.
We synthesized and characterized two novel fluorescent sigma-2 receptor selective ligands, SW120 and SW116, and evaluated these ligands as potential probes for imaging cell proliferation. Both ligands are highly selective for sigma-2 recept...
Fred Reynolds,Kimberly A Kelly
Fred Reynolds
Molecular imaging allows clinicians to visualize disease-specific molecules, thereby providing relevant information in the diagnosis and treatment of patients. With advances in genomics and proteomics and underlying mechanisms of disease pa...
Review
Molecular imaging. 2011 Dec;10(6):407-19. DOI: 2011
Early detection of susceptibility to acute lung inflammation by molecular imaging in mice exposed to cigarette smoke [0.03%]
分子影像技术在早期检测香烟烟雾诱导的小鼠急性肺损伤易感性方面的应用研究
Sandra Pérez-Rial,Laura Del Puerto-Nevado,Nicolás González-Mangado et al.
Sandra Pérez-Rial et al.
Matrix metalloproteinases (MMPs) are extracellular proteolytic enzymes involved in acute lung inflammation in response to cigarette smoke exposure (CSE). We present the in vivo detection of MMP activity using a specific MMP-activatable, nea...
Integrated lymphography using fluorescence imaging and magnetic resonance imaging in intact mice [0.03%]
基于荧光和磁共振淋巴管成像的全身整合活体小鼠淋巴系统图谱
Yusuke Inoue,Yoshitaka Masutani,Shigeru Kiryu et al.
Yusuke Inoue et al.
We assessed lymph drainage in living mice by an integrated imaging method using fluorescence imaging (FLI) and magnetic resonance imaging (MRI). Mice were subcutaneously injected with quantum dots and gadofluorine 8 into the right rear foot...
99mTc-labeled cyclic RGD peptides for noninvasive monitoring of tumor integrin αVβ3 expression [0.03%]
含有99mTc标记的环形RGD肽小分子用于非侵入性监测肿瘤细胞αvβ3整合素表达水平
Yang Zhou,Young-Seung Kim,Sudipta Chakraborty et al.
Yang Zhou et al.
This report describes the biologic evaluations of [99mTc(HYNIC-3P-RGD2)(tricine)(TPPTS)] (99mTc-3P-RGD2: 6-hydrazinonicotinyl; 3P-RGD2 = PEG4-E[PEG4-c(RGDfK)]2; PEG4 = 15-amino-4,7,10,13-tetraoxapentadecanoic acid; and TPPTS = trisodium tri...
Controlled modulation of serum protein binding and biodistribution of asymmetric cyanine dyes by variation of the number of sulfonate groups [0.03%]
通过改变磺酸基团的数量对不对称cyanine染料的血清蛋白结合和生物分布进行控制式调节
Franziska M Hamann,Robert Brehm,Jutta Pauli et al.
Franziska M Hamann et al.
To assess the suitability of asymmetric cyanine dyes for in vivo fluoro-optical molecular imaging, a comprehensive study on the influence of the number of negatively charged sulfonate groups governing the hydrophilicity of the DY-67x family...
Lucia M A Crane,Marleen van Oosten,Rick G Pleijhuis et al.
Lucia M A Crane et al.
Tumor-targeted fluorescence imaging for cancer diagnosis and treatment is an evolving field of research that is on the verge of clinical implementation. As each tumor has its unique biologic profile, selection of the most promising targets ...