Novel positron emission tomography/computed tomography of diffuse parenchymal lung disease combining a labeled somatostatin receptor analogue and 2-deoxy-2[18F]fluoro-D-glucose [0.03%]
新型正电子发射断层显像/体层摄影术结合生长抑素受体类似物和2-脱氧-2-[18F]氟-D-葡萄糖应用于弥漫性肺间质疾病的诊断价值研究
Thida Win,Nicholas J Screaton,Joanna Porter et al.
Thida Win et al.
We prospectively investigated the potential of positron emission tomography (PET) using the somatostatin receptor (SSTR) analogue ⁶⁸Ga-DOTATATE and 2-deoxy-2[¹⁸F]fluoro-D-glucose (¹⁸F-FDG) in diffuse parenchymal lung disease (DPLD). T...
Clinical Trial
Molecular imaging. 2012 Apr;11(2):91-8. DOI: 2012
In vivo evaluation of 1-O-(4-(2-fluoroethyl-carbamoyloxymethyl)-2-nitrophenyl)-O-β-D-glucopyronuronate: a positron emission tomographic tracer for imaging β-glucuronidase activity in a tumor/inflammation rodent model [0.03%]
1-O-(4-(2-氟乙基碳酰氧甲基)-2-硝基苯基)-O-β-D-葡萄吡喃糖苷酸钠：体内正电子发射断层显像剂在肿瘤/炎症动物模型中对β-葡萄糖醛酸酶活性成像的评价
Inês F Antunes,Hidde J Haisma,Philip H Elsinga et al.
Inês F Antunes et al.
β-Glucuronidase (β-GUS) plays an important role in inflammation and degenerative processes. The enzyme has also been investigated as a target in prodrug therapy for cancer. To investigate the role of β-GUS in pathologies and to optimize ...
In vivo evaluation of 1-O-(4-(2-fluoroethyl-carbamoyloxymethyl)-2-nitrophenyl)-O-β-D-glucopyronuronate: a positron emission tomographic tracer for imaging β-glucuronidase activity in a tumor/inflammation rodent model [0.03%]
1-O-(4-(2-氟乙基碳酰氧甲基)-2-硝基苯基)-O-β-D-葡萄吡喃糖苷酸钠盐：体内评价及在肿瘤/炎症模型中的正电子发射断层成像探针应用研究
Inês F Antunes,Hidde J Haisma,Philip H Elsinga et al.
Inês F Antunes et al.
β-Glucuronidase (β-GUS) plays an important role in inflammation and degenerative processes. The enzyme has also been investigated as a target in prodrug therapy for cancer. To investigate the role of β-GUS in pathologies and to optimize ...
Monitoring the induction of heat shock factor 1/heat shock protein 70 expression following 17-allylamino-demethoxygeldanamycin treatment by positron emission tomography and optical reporter gene imaging [0.03%]
利用正电子发射断层成像技术及光学报告基因成像监测17-烯丙基氨基脱甲氧基高棉素诱导的热休克因子1/热休克蛋白70表达
Mikhail Doubrovin,Jian T Che,Inna Serganova et al.
Mikhail Doubrovin et al.
The cell response to proteotoxic cell stresses is mediated primarily through activation of heat shock factor 1 (HSF1). This transcription factor plays a major role in the regulation of the heat shock proteins (HSPs), including HSP70. We dem...
Monitoring the induction of heat shock factor 1/heat shock protein 70 expression following 17-allylamino-demethoxygeldanamycin treatment by positron emission tomography and optical reporter gene imaging [0.03%]
利用正电子发射断层扫描和光学报告基因成像检测17-烯丙基氨基脱甲氧基高奴铵碱诱导的热休克因子1/热休克蛋白70表达
Mikhail Doubrovin,Jian T Che,Inna Serganova et al.
Mikhail Doubrovin et al.
The cell response to proteotoxic cell stresses is mediated primarily through activation of heat shock factor 1 (HSF1). This transcription factor plays a major role in the regulation of the heat shock proteins (HSPs), including HSP70. We dem...
Endothelial adhesion of targeted microbubbles in both small and great vessels using ultrasound radiation force [0.03%]
声波辐射力使靶向微气泡在大血管和小血管内皮黏附
Jia Liu,Ping Zhang,Ping Liu et al.
Jia Liu et al.
The effectiveness of microbubble-mediated ultrasound molecular imaging and drug delivery has been significantly affected by the axial laminar flow of vessels which prevents ultrasound contrast agents (UCAs) from targeting vascular endotheli...
Endothelial adhesion of targeted microbubbles in both small and great vessels using ultrasound radiation force [0.03%]
声辐射力引导下靶向微泡与大小血管内皮的黏附研究
Jia Liu,Ping Zhang,Ping Liu et al.
Jia Liu et al.
The effectiveness of microbubble-mediated ultrasound molecular imaging and drug delivery has been significantly affected by the axial laminar flow of vessels which prevents ultrasound contrast agents (UCAs) from targeting vascular endotheli...
Imaging in vivo extracellular pH with a single paramagnetic chemical exchange saturation transfer magnetic resonance imaging contrast agent [0.03%]
一种用于体内细胞外pH值成像的单个顺磁性化学交换饱和转移磁共振对比剂
Guanshu Liu,Yuguo Li,Vipul R Sheth et al.
Guanshu Liu et al.
The measurement of extracellular pH (pHe) has potential utility for cancer diagnoses and for assessing the therapeutic effects of pH-dependent therapies. A single magnetic resonance imaging (MRI) contrast agent that is detected through para...
Imaging in vivo extracellular pH with a single paramagnetic chemical exchange saturation transfer magnetic resonance imaging contrast agent [0.03%]
一种用于体内细胞外pH值单次参数磁共振成像对比剂的化学交换饱和转移成像法
Guanshu Liu,Yuguo Li,Vipul R Sheth et al.
Guanshu Liu et al.
The measurement of extracellular pH (pHe) has potential utility for cancer diagnoses and for assessing the therapeutic effects of pH-dependent therapies. A single magnetic resonance imaging (MRI) contrast agent that is detected through para...
Rapid visualization of human tumor xenografts through optical imaging with a near-infrared fluorescent anti-epidermal growth factor receptor nanobody [0.03%]
快速光学成像技术在人体肿瘤异种移植体中的应用——用近红外荧光表皮生长因子受体纳米抗体进行可视化标记
Sabrina Oliveira,Guus A M S van Dongen,Marijke Stigter-van Walsum et al.
Sabrina Oliveira et al.
Given that overexpression of the epidermal growth factor receptor (EGFR) is found in many types of human epithelial cancers, noninvasive molecular imaging of this receptor is of great interest. A number of studies have employed monoclonal a...