Feasibility of Na18F PET/CT and MRI for Noninvasive In Vivo Quantification of Knee Pathophysiological Bone Metabolism in a Canine Model of Post-traumatic Osteoarthritis [0.03%]
非侵入性体内定量膝关节创伤后骨关节病病理生理骨代谢的钠氟化钠PET / CT和MRI可行性研究（犬模型）
Maria I Menendez,Bianca Hettlich,Lai Wei et al.
Maria I Menendez et al.
Purpose: To assess and quantify by molecular imaging knee osseous metabolic changes serially in an in vivo canine model of posttraumatic osteoarthritis (PTOA) of the knee utilizing sodium fluoride (Na18F) positron emissio...
Noninvasive Imaging of Immune Checkpoint Ligand PD-L1 in Tumors and Metastases for Guiding Immunotherapy [0.03%]
用于指导免疫治疗的肿瘤和转移灶的非侵入性PD-L1检查点配体成像
Samit Chatterjee,Wojciech G Lesniak,Sridhar Nimmagadda
Samit Chatterjee
Immunotherapy holds great promise in cancer treatment. The challenges in advancing immunotherapies lie in patient stratification and monitoring therapy. Noninvasive detection of immune checkpoint ligand PD-L1 can serve as an important bioma...
Imaging Bone-Cartilage Interactions in Osteoarthritis Using [18F]-NaF PET-MRI [0.03%]
应用[18F]-NaF PET-MRI成像软骨下骨在骨关节炎中的交互作用
Dragana Savic,Valentina Pedoia,Youngho Seo et al.
Dragana Savic et al.
Purpose: Simultaneous positron emission tomography-magnetic resonance imaging (PET-MRI) is an emerging technology providing both anatomical and functional images without increasing the scan time. Compared to the tradition...
Commentary on "A Microfluidic Platform to Design Crosslinked Hyaluronic Acid Nanoparticles (cHANPs) for Enhanced MRI" [0.03%]
“用于增强MRI的交联透明质酸纳米颗粒（cHANP）微流体平台”的评论
Maria Russo,Paolo Bevilacqua,Paolo Antonio Netti et al.
Maria Russo et al.
Strategies to enhance the relaxometric properties of gadolinium (Gd)-based contrast agents (CAs) for magnetic resonance imaging (MRI), without the chemical modification of chelates, have recently had a strong impact on the diagnostic field....
Phosphatidylserine-Targeted Nanotheranostics for Brain Tumor Imaging and Therapeutic Potential [0.03%]
靶向磷脂酰丝氨酸的脑肿瘤诊疗纳米药物的成像和治疗潜力
Lulu Wang,Amyn A Habib,Akiva Mintz et al.
Lulu Wang et al.
Phosphatidylserine (PS), the most abundant anionic phospholipid in cell membrane, is strictly confined to the inner leaflet in normal cells. However, this PS asymmetry is found disruptive in many tumor vascular endothelial cells. We discuss...
Dual-Energy SPECT and the Development of Peptide p5+14 for Imaging Amyloidosis [0.03%]
双能量SPECT及用于淀粉样变性显像的肽p5+14的研发
Jonathan S Wall,Stephen J Kennel,Emily B Martin
Jonathan S Wall
Amyloidosis is associated with a number of rare diseases and is characterized by the deposition, in abdominothoracic organs and peripheral nerves, of extracellular protein fibrils, which leads to dysfunction and severe morbidity. Effective ...
3D Fusion Framework for Infarction and Angiogenesis Analysis in a Myocardial Infarct Minipig Model [0.03%]
用于心肌梗死迷你猪模型的心肌梗死和新生血管形成的三维融合框架
Xu Zhenzhen,Bo Tao,Yu Li et al.
Xu Zhenzhen et al.
The combination of different modality images can provide detailed and comprehensive information for the prognostic assessment and therapeutic strategy of patients with ischemic heart disease. In this study, a 3D fusion framework is designed...
Fluorescent, Plasmonic, and Radiotherapeutic Properties of the 177Lu-Dendrimer-AuNP-Folate-Bombesin Nanoprobe Located Inside Cancer Cells [0.03%]
位于癌细胞内的具有荧光、等离激元及放射治疗性质的177Lu-树枝状聚合物-AuNP-叶酸-布雷泽宾纳米探针
Héctor Mendoza-Nava,Guillermina Ferro-Flores,Flor de María Ramírez et al.
Héctor Mendoza-Nava et al.
The integration of fluorescence and plasmonic properties into one molecule is of importance in developing multifunctional imaging and therapy nanoprobes. The aim of this research was to evaluate the fluorescent properties and the plasmonic-...
Brain and Brown Adipose Tissue Metabolism in Transgenic Tg2576 Mice Models of Alzheimer Disease Assessed Using 18F-FDG PET Imaging [0.03%]
阿尔茨海默病转基因Tg2576小鼠脑和棕色脂肪组织代谢的18F-FDG PET显像研究
Robert A Coleman,Christopher Liang,Rima Patel et al.
Robert A Coleman et al.
Objective: Imaging animal models of Alzheimer disease (AD) is useful for the development of therapeutic drugs and understanding AD. Transgenic Swedish hAPPswe Tg2576 mice are a good model of β-amyloid plaques. We report ...
Imaging of Myocardial Ischemia-Reperfusion Injury Using Sodium [18F]Fluoride Positron Emission Tomography/Computed Tomography in Rats and Humans [0.03%]
使用钠[18F]氟化物正电子发射断层扫描/X线计算机体层成像技术在大鼠和人类中对心肌缺血-再灌注损伤的影像学研究
Hongyoon Choi,Jeong Hee Han,Sue Yeon Lim et al.
Hongyoon Choi et al.
Positron emission tomography (PET)/computed tomography (CT) using sodium [18F]fluoride (Na[18F]F) has been proven to be a promising hot-spot imaging modality for myocardial infarction (MI). We investigated Na[18F]F uptake in ischemia-reperf...