Georg H H Borner
Georg H H Borner
Protein subcellular localization is an essential and highly regulated determinant of protein function. Major advances in mass spectrometry and imaging have allowed the development of powerful spatial proteomics approaches for determining pr...
Katrina Meyer,Matthias Selbach
Katrina Meyer
Protein-protein interactions are often mediated by short linear motifs (SLiMs) that are located in intrinsically disordered regions (IDRs) of proteins. Interactions mediated by SLiMs are notoriously difficult to study, and many functionally...
Katrina Meyer,Matthias Selbach
Katrina Meyer
Protein-protein interactions are often mediated by short linear motifs (SLiMs) that are located in intrinsically disordered regions (IDRs) of proteins. Interactions mediated by SLiMs are notoriously difficult to study, and many functionally...
Flow-induced Reorganization of Laminin-integrin Networks Within the Endothelial Basement Membrane Uncovered by Proteomics [0.03%]
基于蛋白质组学发现的血管内皮下层基膜中层粘连蛋白-整合素网路的流动重排现象
Eelke P Béguin,Esmée F J Janssen,Mark Hoogenboezem et al.
Eelke P Béguin et al.
The vessel wall is continuously exposed to hemodynamic forces generated by blood flow. Endothelial mechanosensors perceive and translate mechanical signals via cellular signaling pathways into biological processes that control endothelial d...
Flow-induced Reorganization of Laminin-integrin Networks Within the Endothelial Basement Membrane Uncovered by Proteomics [0.03%]
基于组学的蛋白质组分析发现流体剪切力引起血管内皮下层层粘连蛋白-整合素网络的重构
Eelke P Béguin,Esmée F J Janssen,Mark Hoogenboezem et al.
Eelke P Béguin et al.
The vessel wall is continuously exposed to hemodynamic forces generated by blood flow. Endothelial mechanosensors perceive and translate mechanical signals via cellular signaling pathways into biological processes that control endothelial d...
A Cross-linking Mass Spectrometry Approach Defines Protein Interactions in Yeast Mitochondria [0.03%]
一种交联质谱方法确定酵母线粒体中的蛋白质相互作用
Andreas Linden,Markus Deckers,Iwan Parfentev et al.
Andreas Linden et al.
Protein cross-linking and the analysis of cross-linked peptides by mass spectrometry is currently receiving much attention. Not only is this approach applied to isolated complexes to provide information about spatial arrangements of protein...
A Cross-linking Mass Spectrometry Approach Defines Protein Interactions in Yeast Mitochondria [0.03%]
一种交联质谱方法确定酵母线粒体中的蛋白质相互作用
Andreas Linden,Markus Deckers,Iwan Parfentev et al.
Andreas Linden et al.
Protein cross-linking and the analysis of cross-linked peptides by mass spectrometry is currently receiving much attention. Not only is this approach applied to isolated complexes to provide information about spatial arrangements of protein...
Robust Summarization and Inference in Proteome-wide Label-free Quantification [0.03%]
稳健的蛋白质组无标签定量求和及推理
Adriaan Sticker,Ludger Goeminne,Lennart Martens et al.
Adriaan Sticker et al.
Label-Free Quantitative mass spectrometry based workflows for differential expression (DE) analysis of proteins impose important challenges on the data analysis because of peptide-specific effects and context dependent missingness of peptid...
Robust Summarization and Inference in Proteome-wide Label-free Quantification [0.03%]
稳健的全蛋白质组非标记定量摘要和推理
Adriaan Sticker,Ludger Goeminne,Lennart Martens et al.
Adriaan Sticker et al.
Label-Free Quantitative mass spectrometry based workflows for differential expression (DE) analysis of proteins impose important challenges on the data analysis because of peptide-specific effects and context dependent missingness of peptid...
HIGD2A is Required for Assembly of the COX3 Module of Human Mitochondrial Complex IV [0.03%]
HIGD2A是人类线粒体复合物IV的COX3模块装配所必需的蛋白质
Daniella H Hock,Boris Reljic,Ching-Seng Ang et al.
Daniella H Hock et al.
Assembly factors play a critical role in the biogenesis of mitochondrial respiratory chain complexes I-IV where they assist in the membrane insertion of subunits, attachment of co-factors, and stabilization of assembly intermediates. The ma...