The Mouse Heart Mitochondria N Terminome Provides Insights into ClpXP-Mediated Proteolysis [0.03%]
小鼠心肌线粒体N末端组学揭示ClpXP介导的蛋白降解的新底物
Eduard Hofsetz,Fatih Demir,Karolina Szczepanowska et al.
Eduard Hofsetz et al.
The mammalian mitochondrial proteome consists of more than 1100 annotated proteins and their proteostasis is regulated by only a few ATP-dependent protease complexes. Technical advances in protein mass spectrometry allowed for detailed desc...
Differential Complex Formation via Paralogs in the Human Sin3 Protein Interaction Network [0.03%]
人类Sin3蛋白质相互作用网络中同源物介导的复合体形成
Mark K Adams,Charles A S Banks,Janet L Thornton et al.
Mark K Adams et al.
Despite the continued analysis of HDAC inhibitors in clinical trials, the heterogeneous nature of the protein complexes they target limits our understanding of the beneficial and off-target effects associated with their application. Among t...
Differential Complex Formation via Paralogs in the Human Sin3 Protein Interaction Network [0.03%]
人类Sin3蛋白质相互作用网络中同源蛋白形成差异复合体机制研究
Mark K Adams,Charles A S Banks,Janet L Thornton et al.
Mark K Adams et al.
Despite the continued analysis of HDAC inhibitors in clinical trials, the heterogeneous nature of the protein complexes they target limits our understanding of the beneficial and off-target effects associated with their application. Among t...
Identification of Tumor Antigens in the HLA Peptidome of Patient-derived Xenograft Tumors in Mouse [0.03%]
通过小鼠人源异种移植肿瘤的HLA肽组鉴定肿瘤抗原
Nataly Mancette Rijensky,Netta R Blondheim Shraga,Eilon Barnea et al.
Nataly Mancette Rijensky et al.
Personalized cancer immunotherapy targeting patient-specific cancer/testis antigens (CTA) and neoantigens may benefit from large-scale tumor human leukocyte antigen (HLA) peptidome (immunopeptidome) analysis, which aims to accurately identi...
Identification of Tumor Antigens in the HLA Peptidome of Patient-derived Xenograft Tumors in Mouse [0.03%]
利用移植瘤小鼠鉴定患者肿瘤异种移植瘤HLA肽组中的抗原
Nataly Mancette Rijensky,Netta R Blondheim Shraga,Eilon Barnea et al.
Nataly Mancette Rijensky et al.
Personalized cancer immunotherapy targeting patient-specific cancer/testis antigens (CTA) and neoantigens may benefit from large-scale tumor human leukocyte antigen (HLA) peptidome (immunopeptidome) analysis, which aims to accurately identi...
The Aspergillus fumigatus Secretome Alters the Proteome of Pseudomonas aeruginosa to Stimulate Bacterial Growth: Implications for Co-infection [0.03%]
烟曲霉分泌组改变绿脓杆菌蛋白质组以促进细菌生长：共感染的含义
Anatte Margalit,James C Carolan,David Sheehan et al.
Anatte Margalit et al.
Individuals with cystic fibrosis are susceptible to co-infection by Aspergillus fumigatus and Pseudomonas aeruginosa Despite the persistence of A. fumigatus in the cystic fibrosis lung P. aeruginosa eventually predominates as the primary pa...
The Aspergillus fumigatus Secretome Alters the Proteome of Pseudomonas aeruginosa to Stimulate Bacterial Growth: Implications for Co-infection [0.03%]
烟曲霉分泌组改变绿脓杆菌蛋白质组以促进细菌生长：共感染的启示
Anatte Margalit,James C Carolan,David Sheehan et al.
Anatte Margalit et al.
Individuals with cystic fibrosis are susceptible to co-infection by Aspergillus fumigatus and Pseudomonas aeruginosa Despite the persistence of A. fumigatus in the cystic fibrosis lung P. aeruginosa eventually predominates as the primary pa...
Alerie G de la Fuente,Rayner M L Queiroz,Tanay Ghosh et al.
Alerie G de la Fuente et al.
Following central nervous system (CNS) demyelination, adult oligodendrocyte progenitor cells (OPCs) can differentiate into new myelin-forming oligodendrocytes in a regenerative process called remyelination. Although remyelination is very ef...
Changes in the Oligodendrocyte Progenitor Cell Proteome with Ageing [0.03%]
oligodendrocyte前体细胞蛋白组的年龄变化
Alerie G de la Fuente,Rayner M L Queiroz,Tanay Ghosh et al.
Alerie G de la Fuente et al.
Following central nervous system (CNS) demyelination, adult oligodendrocyte progenitor cells (OPCs) can differentiate into new myelin-forming oligodendrocytes in a regenerative process called remyelination. Although remyelination is very ef...
Dynamic Transcriptomic and Phosphoproteomic Analysis During Cell Wall Stress in Aspergillus nidulans [0.03%]
细胞壁压力下曲霉菌的动态转录组和磷酸蛋白质组学分析
Cynthia Chelius,Walker Huso,Samantha Reese et al.
Cynthia Chelius et al.
The fungal cell-wall integrity signaling (CWIS) pathway regulates cellular response to environmental stress to enable wall repair and resumption of normal growth. This complex, interconnected, pathway has been only partially characterized i...