The Insulin Receptor Adaptor IRS2 is an APC/C Substrate That Promotes Cell Cycle Protein Expression and a Robust Spindle Assembly Checkpoint [0.03%]
胰岛素受体衔接蛋白IRS2是APC/C底物，可促进细胞周期蛋白的表达并增强纺锤体组装检验点功能
Sandhya Manohar,Qing Yu,Steven P Gygi et al.
Sandhya Manohar et al.
Insulin receptor substrate 2 (IRS2) is an essential adaptor that mediates signaling downstream of the insulin receptor and other receptor tyrosine kinases. Transduction through IRS2-dependent pathways is important for coordinating metabolic...
An Interaction Network of RNA-Binding Proteins Involved in Drosophila Oogenesis [0.03%]
参与果蝇卵生成的RNA结合蛋白互作网络
Prashali Bansal,Johannes Madlung,Kristina Schaaf et al.
Prashali Bansal et al.
During Drosophila oogenesis, the localization and translational regulation of maternal transcripts relies on RNA-binding proteins (RBPs). Many of these RBPs localize several mRNAs and may have additional direct interaction partners to regul...
An Interaction Network of RNA-Binding Proteins Involved in Drosophila Oogenesis [0.03%]
参与果蝇卵生成的RNA结合蛋白互作网络
Prashali Bansal,Johannes Madlung,Kristina Schaaf et al.
Prashali Bansal et al.
During Drosophila oogenesis, the localization and translational regulation of maternal transcripts relies on RNA-binding proteins (RBPs). Many of these RBPs localize several mRNAs and may have additional direct interaction partners to regul...
Kir2.1 Interactome Mapping Uncovers PKP4 as a Modulator of the Kir2.1-Regulated Inward Rectifier Potassium Currents [0.03%]
Kir2.1蛋白质相互作用组研究发现PKP4调节Kir2.1介导的钾离子内向整流电流
Sung-Soo Park,Daniela Ponce-Balbuena,Rork Kuick et al.
Sung-Soo Park et al.
Kir2.1, a strong inward rectifier potassium channel encoded by the KCNJ2 gene, is a key regulator of the resting membrane potential of the cardiomyocyte and plays an important role in controlling ventricular excitation and action potential ...
Kir2.1 Interactome Mapping Uncovers PKP4 as a Modulator of the Kir2.1-Regulated Inward Rectifier Potassium Currents [0.03%]
Kir2.1蛋白质相互作用组研究发现PKP4调节Kir2.1介导的钾离子内向整流电流
Sung-Soo Park,Daniela Ponce-Balbuena,Rork Kuick et al.
Sung-Soo Park et al.
Kir2.1, a strong inward rectifier potassium channel encoded by the KCNJ2 gene, is a key regulator of the resting membrane potential of the cardiomyocyte and plays an important role in controlling ventricular excitation and action potential ...
Steven T Bruckbauer,Benjamin B Minkoff,Deyang Yu et al.
Steven T Bruckbauer et al.
Recent work has begun to investigate the role of protein damage in cell death because of ionizing radiation (IR) exposure, but none have been performed on a proteome-wide basis, nor have they utilized MS (MS) to determine chemical identity ...
Steven T Bruckbauer,Benjamin B Minkoff,Deyang Yu et al.
Steven T Bruckbauer et al.
Recent work has begun to investigate the role of protein damage in cell death because of ionizing radiation (IR) exposure, but none have been performed on a proteome-wide basis, nor have they utilized MS (MS) to determine chemical identity ...
Depolarization-dependent Induction of Site-specific Changes in Sialylation on N- linked Glycoproteins in Rat Nerve Terminals [0.03%]
去极化诱导的大鼠神经末端N连接糖蛋白特定部位岩藻糖基化的位点特异性变化
Inga Boll,Pia Jensen,Veit Schwämmle et al.
Inga Boll et al.
Synaptic transmission leading to release of neurotransmitters in the nervous system is a fast and highly dynamic process. Previously, protein interaction and phosphorylation have been thought to be the main regulators of synaptic transmissi...
Depolarization-dependent Induction of Site-specific Changes in Sialylation on N- linked Glycoproteins in Rat Nerve Terminals [0.03%]
去极化诱导大鼠神经终末神经细胞聚糖脱唾液酸化的位点特异性变化及其依赖性研究
Inga Boll,Pia Jensen,Veit Schwämmle et al.
Inga Boll et al.
Synaptic transmission leading to release of neurotransmitters in the nervous system is a fast and highly dynamic process. Previously, protein interaction and phosphorylation have been thought to be the main regulators of synaptic transmissi...
The Mouse Heart Mitochondria N Terminome Provides Insights into ClpXP-Mediated Proteolysis [0.03%]
小鼠心脏线粒体N末端组学揭示ClpXP介导的蛋白降解的新见解
Eduard Hofsetz,Fatih Demir,Karolina Szczepanowska et al.
Eduard Hofsetz et al.
The mammalian mitochondrial proteome consists of more than 1100 annotated proteins and their proteostasis is regulated by only a few ATP-dependent protease complexes. Technical advances in protein mass spectrometry allowed for detailed desc...