Capivasertib in Hormone Receptor-Positive, Human Epidermal Growth Factor Receptor 2-Negative advanced breast cancer [0.03%]
用于激素受体阳性、人表皮生长因子受体2阴性的晚期乳腺癌的capivasertib治疗
Zaheer Qureshi,Faryal Altaf,Mikail Khanzada et al.
Zaheer Qureshi et al.
Purpose: This review discusses the role and efficacy of Capivasertib in managing Hormone Receptor-Positive (HR+) breast cancer. Summary: ...
The predictive value of hematological inflammatory markers for severe oral mucositis in patients with nasopharyngeal carcinoma during intensity-modulated radiation therapy: A retrospective cohort study [0.03%]
预测血液炎症标志物对鼻咽癌患者在接受调强放射治疗期间发生严重口腔黏膜炎的价值：一项回顾性队列研究
Xiaoxian Huang,Xinling Qin,Weimei Huang et al.
Xiaoxian Huang et al.
Background: This study aims to investigate the predictive value of the circulating blood cell count, including neutro-philto-lymphocyte ratio (NLR), platelet-to-lymphocyte (PLR), and thesystemic inflammation index (SII) f...
Prognostic risk stratification using C-reactive protein, albumin, and associated inflammatory biomarkers in patients with advanced cancer in palliative care [0.03%]
晚期恶性肿瘤姑息治疗患者C反应蛋白、白蛋白及相关的炎症生物标志物预后风险分层模型
Geisiane Alves da Silva,Livia Costa de Oliveira,Emanuelly Varea Maria Wiegert et al.
Geisiane Alves da Silva et al.
Purpose: To evaluate the prognostic value of C-reactive protein (CRP), albumin, CRP/albumin ratio (CAR), and modified Glasgow Prognostic Score (mGPS) at different thresholds in patients with advanced cancer in palliative ...
Ethan Harris,Rajat Thawani
Ethan Harris
NSCLC has a diverse genomic background with mutations in key proto-oncogenic drivers including Kirsten rat sarcoma (KRAS) and epidermal growth factor receptor (EGFR). Roughly 40% of adenocarcinoma harbor Kras activating mutations regardless...
High-grade neuroendocrine head and neck cancer: Case series and review of the literature [0.03%]
高级神经内分泌头颈癌：病例系列和文献综述
Javier David Benitez Fuentes,Sally Fouda,Elin Evans et al.
Javier David Benitez Fuentes et al.
Background: High-grade neuroendocrine cancers (NEC) of the head and neck (HN) are rare and aggressive, accounting for ≤1 % of all HN cancers, with a 5-year overall survival (OS) of ≤20 %. This case series examines clini...
The intratumor microbiome varies by geographical location and anatomical site in head and neck squamous cell carcinoma [0.03%]
地理位置和解剖部位影响头颈部鳞状细胞癌内肿瘤微生物群的分布
Rishabh Yalamarty,Shruti Magesh,Daniel John et al.
Rishabh Yalamarty et al.
Head and Neck Squamous Cell Carcinoma (HNSCC) is a highly heterogeneous cancer that is characterized by distinct phenotypes based on anatomical site and etiological agents. Recently, the intratumor microbiome has been implicated in cancer p...
Primary and secondary prevention of cervical cancer among Italian AFAB transgender people [0.03%]
意大利AFAB变性人宫颈癌的一级和二级预防
Alessandra Lami,Stefania Alvisi,Arianna Siconolfi et al.
Alessandra Lami et al.
Objective: Currently, available data on preventive measures for Human Papillomavirus (HPV) infection and cervical cancer in the transgender assigned female at birth (AFAB) community are extremely limited. Our aim was to a...
Prognostic significance of HER2 loss after HER2-targeted neoadjuvant treatment in patients with HER2-positive locally advanced breast cancer [0.03%]
HER2阳性局部晚期乳腺癌患者行抗HER2新辅助治疗后丢失的预后意义
Yasin Kutlu,Ruhper Cekin,Sabin Goktas Aydin et al.
Yasin Kutlu et al.
Loss of human epidermal growth factor receptor 2 (HER2) expression can be seen in almost 25-30 % patients after HER2 receptor directed neoadjuvant treatment. These patients have unclear clinical outcomes in previous studies. We aimed to inv...
Multicenter Study
Current problems in cancer. 2024 Jun:50:101102. DOI:10.1016/j.currproblcancer.2024.101102 2024
Prognostic significance of SIRI in patients with late-stage lung adenocarcinoma receiving EGFR-TKI treatment [0.03%]
SIRI在EGFR-TKI治疗的晚期肺腺癌患者中的预后价值
Herong Wang,Wei Li
Herong Wang
Objective: In this study, we examined the relationship between the Systemic Inflammatory Response Index (SIRI) and the overall prognosis of patients with late-stage lung adenocarcinoma who harbor epidermal growth factor r...
Germline and somatic mutations in prostate cancer: Implications for treatment [0.03%]
前列腺癌的胚系和体细胞突变及其治疗意义
Cameron Chalker,Brie Chun,Alexandra O Sokolova
Cameron Chalker
Genetic testing is an integral part of the workup of metastatic prostate cancer, in part, because the results can have a profound impact on the subsequent management of this disease. There are now several Food & Drug Administration (FDA) ap...