Metaplastic breast cancer: Experience with ifosfamide based chemotherapy [0.03%]
化疗使用异环磷酰胺治疗_meta型乳腺癌的经验
Nidhi Gupta,Shifali Dogra,Kislay Dimri et al.
Nidhi Gupta et al.
Background: Metaplastic breast cancer (MPBC) is a rare variant of breast cancer and most treatment protocols are based on the guidelines for triple negative breast cancer. However, response to standard anthracycline and t...
Mapping the intricacies of GLI1 in hedgehog signaling: A combined bioinformatics and clinical analysis in Head & Neck cancer in Western India [0.03%]
GLI1的复杂性在 Hedgehog 信号传导中的图谱：印度西部头颈部癌症的生物信息学和临床分析相结合的方法
Hitarth V Patel,Franky D Shah
Hitarth V Patel
Background: Activation of various cancer stem cell pathways are thought to be responsible for treatment failure and loco-regional recurrence in Head and Neck cancer. Hedgehog signaling, a major cancer stem signaling pathw...
ROS1-rearranged non-small cell lung cancer: Understanding biology and optimizing management in the era of new approvals [0.03%]
ROS1重排非小细胞肺癌：理解生物学特性及在新药获批时代的治疗优化
Nathaniel J Myall,Millie Das
Nathaniel J Myall
Rearrangements involving the ROS1 gene are infrequent in non-small cell lung cancer (NSCLC) but represent an important targetable driver alteration. Occurring most commonly in patients with adenocarcinoma who have a light or never smoking h...
Nadine Mallak,Burcak Yilmaz,Catherine Meyer et al.
Nadine Mallak et al.
Advancements in somatostatin receptor (SSTR) targeted imaging and treatment of well-differentiated neuroendocrine tumors (NETs) have revolutionized the management of these tumors. This comprehensive review delves into the current practice, ...
Amr Wahba,Zi Tan,Joseph S Dillon
Amr Wahba
Functional neuroendocrine neoplasms (NENs) are those associated with specific symptoms related to the hormonal secretion of the NENs. Although less than 25 % of NENs are functional at diagnosis,1 the associated syndromes significantly incre...
Kristin Trone,Rodney Pommier
Kristin Trone
Madelaine Hack,Castigliano M Bhamidipati
Madelaine Hack
Carcinoid Heart Disease (CaHD) is defined as the constellation of all cardiac manifestations that occur in patients with carcinoid tumors. Cardiac manifestations are generally due to the paraneoplastic effects of vasoactive substances secre...
Gastroenteropancreatic neuroendocrine tumors: Epigenetic landscape and clinical implications [0.03%]
胃肠道胰神经内分泌肿瘤：表观遗传景观与临床意义
Hannah S McMurry,Jaydira Del Rivero,Emerson Y Chen et al.
Hannah S McMurry et al.
Neuroendocrine tumors (NETs) are a rare, heterogenous group of neoplasms arising from cells of the neuroendocrine system. Amongst solid tumor malignancies, NETs are notable for overall genetic stability and recent data supports the notion t...
Management of metastatic pheochromocytomas and paragangliomas: when and what [0.03%]
转移性嗜铬细胞瘤和副神经节瘤的治疗：何时以及如何治疗？
Vineeth Sukrithan,Kimberly Perez,Neeta Pandit-Taskar et al.
Vineeth Sukrithan et al.
Recently, the treatment landscape for metastatic pheochromocytomas and paragangliomas (MPPGL) has seen both progress and setbacks. We provide an up-to-date review of the multimodality management of MPPGL and discuss novel opportunities and ...
Peng Liu,Chaowen Shi,Lipeng Qiu et al.
Peng Liu et al.
To date, mounting evidence have shown that patients with multiple endocrine neoplasia type 1 (MEN1) may face an increased risk for breast carcinogenesis. The product of the MEN1 gene, menin, was also indicated to be an important regulator i...