Clinicopathological profile and treatment outcomes of advanced/unresectable thymic malignancies from a tertiary care centre in India [0.03%]
印度三级医疗中心晚期/不可切除胸腺恶性肿瘤的临床病理特征和治疗结果
Swasthik Upadhya,Jayashimman Vasanthraman,Aparna Sharma et al.
Swasthik Upadhya et al.
Background: Thymomas, though rare, are the most common anterior mediastinal neoplasms in adults, with incidence of 0.13 per 100,000 person-years. Due to indolent nature and lack of randomized trials, treatment relies on r...
Blinatumomab versus chemotherapy in pediatric B-ALL: A meta-analysis of randomized trials in relapsed and high-risk frontline disease [0.03%]
儿科B细胞急性淋巴细胞白血病复发和高危初诊患者中Blina单抗与化疗的对比：随机试验Meta分析
Adeena Musheer,Muhammad Shaheer Mannan,Muhammad Waqas Khan et al.
Adeena Musheer et al.
Background: B-cell acute lymphoblastic leukemia (B-ALL) is the most common pediatric cancer, comprising almost 25 % of childhood malignancies. Despite advances in chemotherapy, relapse remains a major cause of treatment f...
Multicenter retrospective study on the clinical profiles of patients with extensive-stage small-cell lung cancer who met the eligibility criteria for clinical trials [0.03%]
多中心回顾性分析广泛期小细胞肺癌临床试验合格患者的临床特征
Tatsuya Yazaki,Kei Sonehara,Toshiharu Tsutsui et al.
Tatsuya Yazaki et al.
Background: Chemoimmunotherapy is the standard first-line treatment for extensive-stage small-cell lung cancer (ES-SCLC); however, a limited number of real-world cases meet the inclusion and exclusion criteria of clinical...
BATPC: A biology-anchored tumor progression classification for interpreting multidimensional progression phenotypes across solid tumors [0.03%]
基于生物学的肿瘤进展分类：解释实体瘤多维度进展表型
Yogesh Kumar Gupta
Yogesh Kumar Gupta
Background: Conventional size-based criteria such as RECIST collapse biologically diverse progression patterns into a single "progressive disease" label, obscuring clinically meaningful heterogeneity. As multimodal monito...
Predictors of pathological upgrading in low-risk gleason grade group 1 prostate cancer on prostate biopsy: the role of clinical and tumor-specific factors [0.03%]
低危Gleason 1组前列腺癌患者病理恶变的预测因素：临床及肿瘤特异性因素的作用
Shirin Razdan,Ali Fathollahi,Alexandre Armache et al.
Shirin Razdan et al.
Objective: Gleason Grade Group (GG) 1 prostate cancer (PCa) with PSA 8.1%, presence of atypical small acinar proliferation (ASAP) or intraductal carcinoma (IDC) on biopsy. ...
Genomic risk distribution, adjuvant chemotherapy trends, and survival outcomes in women with pT1, grade 1-2, ER/PR-positive, LVI-negative breast cancer [0.03%]
pT1期、Grade 1-2、ER/PR阳性、LVI阴性乳腺癌患者的基因组风险分布、辅助化疗趋势和生存结局
Nickolas Stabellini,Maya Lubarsky,Ananya Munjal et al.
Nickolas Stabellini et al.
Background: Oncotype DX Recurrence Score (RS) guides adjuvant chemotherapy decisions in early-stage hormone receptor-positive (HR+), HER2-negative breast cancer (BC). However, the survival benefit of adjuvant chemotherapy...
Morgan Terry,Alex Lichtl,Peiran Zhou et al.
Morgan Terry et al.
Head and neck squamous cell carcinoma (HNSCC) is a pathology that necessitates collaborative care and multidisciplinary management. There is a role for timely surgical involvement which evolves at different stages of disease progression. Up...
Clinical impact of a single time-point protocol paired FDG-PET and radioactive iodine scan for comprehensive disease assessment in differentiated thyroid cancer [0.03%]
一次显像配对18F-FDG PET和放射性碘扫描全面评估分化型甲状腺癌病情的临床价值
Margaret Locke,Charit Taneja,Mehdi Djekidel et al.
Margaret Locke et al.
Background: Treatment decisions in advanced or metastatic differentiated thyroid cancer require comprehensive clinical, genomic, and imaging evaluations. FDG-PET and radioactive iodine (RAI) scans image different biologic...
Patterns of care for older multiple myeloma patients in the U.S.: An analysis of the national cancer database [0.03%]
美国老年人多重骨髓瘤治疗模式的分析：基于国家癌症数据库的研究
Muni Rubens,Jeremy Purow,Daniel M Portnoy et al.
Muni Rubens et al.
This study highlights the vital role of personalized treatment strategies in managing multiple myeloma (MM) among older patients, a population greatly affected by this disease. We conducted a retrospective analysis using data from the Natio...
Too late to fall: Time to PSA nadir and early oncologic failure after cryotherapy and high-intensity focused ultrasound for localized prostate cancer [0.03%]
前列腺癌患者经cryotherapy和高强度聚焦超声治疗后PSA最低值的时间及早期肿瘤失败的多变量分析
Umberto Anceschi,Salvatore Basile,Leonardo Misuraca et al.
Umberto Anceschi et al.
Introduction: The ability of time to PSA nadir (TTN) to predict early treatment failure after focal therapy for prostate cancer remains unclear. We assessed whether TTN and PSA nadir-related parameters are associated with...