Best Practices in the Development and Use of Experimental Models of Bacterial Pneumonia: An Official American Thoracic Society Workshop Report [0.03%]
美国胸科医师学会官方关于细菌性肺炎实验模型开发和应用最佳实践的研讨会报告
Amali E Samarasinghe,Scott H Randell,Hrishikesh S Kulkarni et al.
Amali E Samarasinghe et al.
The global incidence of respiratory infectious diseases caused by bacteria continues to increase, with acute lower respiratory tract infections contributing to significant morbidity and mortality. Preclinical models designed to investigate ...
Hermansky-Pudlak Syndrome Pulmonary Fibrosis: Monogenic Disorder, Multi-omics Discovery [0.03%]
赫尔曼斯基-普杜拉综合征肺纤维化：单基因异常介导的多组学改变
Alexander Ghincea,Erica L Herzog
Alexander Ghincea
Siglec-F Deficiency Prevents Fibrosis after Bleomycin-induced Acute Lung Injury [0.03%]
Siglec-F缺乏可防止博来霉素诱导的急性肺损伤后的纤维化发生
Marika Orlov,Naoko Hara,Sunad Rangarajan et al.
Marika Orlov et al.
Single-Cell Multiome Impact of Prenatal Heavy Metal Exposure on Early Airway Development [0.03%]
孕期重金属暴露对早期气道发育的单细胞多组学影响
Boris Minasenko,Dongxue Wang,Jessica Chan et al.
Boris Minasenko et al.
Prenatal exposure to cadmium (Cd) and arsenic (As) can severely impair fetal lung development, leading to lifelong adverse effects. As two of the most common and toxic heavy metals, Cd and As pose risks to many communities through food and ...
Influenza A Virus Following Radiotherapy Amplifies Lung Injury and Monocyte-derived Macrophage Responses [0.03%]
放射治疗后的流感A病毒加重肺损伤和单核细胞来源的巨噬细胞反应
Angela M Groves,Carl J Johnston,Nicole D Paris et al.
Angela M Groves et al.
Improvements in radiation therapy (RT) for thoracic cancers have increased survival, thus preventing radiotoxicity in normal lung tissue becomes even more important. Respiratory infection is a lung stressor that increases the risk of RT tox...
Yung-An Huang,Taylor A Doherty
Yung-An Huang
Wenjie Wang,Shiyi Chen,Zhuyi Xi et al.
Wenjie Wang et al.
Idiopathic pulmonary fibrosis (IPF) is a chronic, progressive, interstitial lung disease lacking efficient drug to reverse it. Thus, to elucidate the complex pathogenesis of IPF and identify new therapeutic targets are urgently needed. It h...
Hyaluronan Ameliorates Viral Pneumonia in Mice and Humans by Inhibiting E2F1 Transcription Factor [0.03%]
透明质酸通过抑制E2F1转录因子改善病毒性肺炎
Vandy P Stober,Carol S Trempus,Flavia Galdi et al.
Vandy P Stober et al.
Rationale: Viral lung infections are a major cause of morbidity and mortality worldwide. Despite significant advances in vaccines and antivirals, there remains a tremendous need for broadly applicable treatments that can ...