Inês Cabrita,Roberta Benedetto,Podchanart Wanitchakool et al.
Inês Cabrita et al.
TMEM16A is a Ca2+-activated chloride channel that was shown to enhance production and secretion of mucus in inflamed airways. It is, however, not clear whether TMEM16A directly supports mucus production, or whether mucin and TMEM16A are upr...
Lung Expression of Human Angiotensin-Converting Enzyme 2 Sensitizes the Mouse to SARS-CoV-2 Infection [0.03%]
人血管紧张素转换酶2在小鼠肺部的表达使其对SARS-CoV-2感染更敏感
Kun Han,Robert V Blair,Naoki Iwanaga et al.
Kun Han et al.
Preclinical mouse models that recapitulate some characteristics of coronavirus disease (COVID-19) will facilitate focused study of pathogenesis and virus-host responses. Human agniotensin-converting enzyme 2 (hACE2) serves as an entry recep...
Aspergillusfumigatus Recognition by Dendritic Cells Negatively Regulates Allergic Lung Inflammation through a TLR2/MyD88 Pathway [0.03%]
树突细胞通过TLR2 / MyD88通路对Aspergillusfumigatus的识别负调节过敏性肺部炎症
Pauline Percier,Sofie De Prins,Giresse Tima et al.
Pauline Percier et al.
Aspergillus fumigatus is an opportunistic fungal pathogen responsible for a spectrum of clinical manifestations. Dendritic cells recognize pathogen-associated molecular patterns of Aspergillus via two main receptor families, Toll-like recep...
The Interplay of the Genetic Architecture, Aging, and Environmental Factors in the Pathogenesis of Idiopathic Pulmonary Fibrosis [0.03%]
遗传结构、环境因素和年龄在特发性肺纤维化发病机制中的相互作用
Annie Pardo,Moisés Selman
Annie Pardo
Idiopathic pulmonary fibrosis (IPF) is a chronic fibrosing lung disease of indeterminate etiology and limited therapeutic options. The initiation, development, and progression of IPF are influenced by genetic predisposition, aging, and host...
Effects of Asthma and Human Rhinovirus A16 on the Expression of SARS-CoV-2 Entry Factors in Human Airway Epithelium [0.03%]
哮喘和人鼻病毒A16对人类呼吸道上皮中SARS-CoV-2 入口因素表达的影响
Ryan C Murphy,Ying Lai,Kaitlyn A Barrow et al.
Ryan C Murphy et al.
Enid R Neptune,Sharon McGrath-Morrow
Enid R Neptune
Baktybek Kojonazarov
Baktybek Kojonazarov
Stiffness of the Extracellular Matrix: A Regulator of Prostaglandins in Pulmonary Fibrosis? [0.03%]
细胞外基质的刚性：肺纤维化中前列腺素的调节者？
Katharina Jandl,Grazyna Kwapiszewska
Katharina Jandl