Lactylation-YTHDF1 Axis Promotes DNAH5-dependent Ciliary Defense in Pseudomonas aeruginosa Infection [0.03%]
乳酰化-YTHDF1轴促进Pseudomonas aeruginosa感染依赖DNAH5的纤毛防御作用
Jing Wang,Xiang Shen,Yanan Li et al.
Jing Wang et al.
Pseudomonas aeruginosa infection poses a significant clinical challenge in respiratory diseases by subverting host defense mechanisms. While inflammatory responses in airway epithelial cells (AECs) during infection have been extensively stu...
C-Type Lectin-Like Receptor 2 in Lung Epithelium Protects Against Acute Lung Injury [0.03%]
肺上皮中的C型凝集素样受体2对急性肺损伤具有保护作用
Tian Jiang,Linfeng Wu,Ying Wang et al.
Tian Jiang et al.
C-type lectin-like receptor 2 (CLEC2) is a transmembrane receptor highly expressed on platelets which regulates platelet aggregation and immune response. Yet, the function of CLEC2 in lung epithelium and its contribution to acute lung injur...
Pathologic Wall Shear Stress in the Trachea Decreases Epithelial Differentiation and Increases Fibrosis [0.03%]
病理性的剪切应力通过改变气管上皮细胞分化来促进纤维化发生
Sayali Dharmadhikari,Jazmin Calyeca,Lumei Liu et al.
Sayali Dharmadhikari et al.
Mechanical ventilation is integral to the medical management of the critically ill. However, prolonged exposure to pathologic airflow during mechanical ventilation places patients at risk for airway injury. Here, we developed an innovative ...
Circular RNAs Are Differentially Expressed in Cystic Fibrosis Bronchial Epithelium and Regulate Ion Conductance [0.03%]
圆环RNA在囊性纤维化支气管上皮中差异表达并调节离子传导
Chiara De Santi,Joshua E Donovan,Eimear Fay et al.
Chiara De Santi et al.
YAP Deficiency Drives NF-κB Hyperactivation to Disrupt Airway Epithelium Differentiation in Congenital Diaphragmatic Hernia [0.03%]
YAP缺陷通过激活NF-κB通路来干扰膈疝的气道上皮分化
Ophelia Aubert,Gaurang M Amonkar,Xaralabos Varelas et al.
Ophelia Aubert et al.
Pulmonary Artery Endothelial Cells from Patients with Pulmonary Arterial Hypertension Exhibit Heterogeneous Responses to Their Mechanical Microenvironment [0.03%]
来自肺动脉高压患者的肺动脉内皮细胞对其机械微环境的反应具有异质性
Sunita S Paudel,Navneet Singh,Dhananjay T Tambe et al.
Sunita S Paudel et al.
CCL18 with an Attitude: Unlocking the Role of Macrophage CCL18 in Checkpoint Inhibitor Pneumonitis [0.03%]
带有态度的CCL18：解锁巨噬细胞CCL18在检查点抑制剂肺炎中的作用
Nathanial J Tolman,William Bain
Nathanial J Tolman