L-Glutamine attenuates peritoneal fibrosis developed in 5-Fluorouracil-treated mice [0.03%]
L-谷氨酰胺能缓解5-氟尿嘧啶致小鼠腹膜纤维化的发展
Juliana Francisca Grossi Heleno,Leticia Cristine Cardoso Dos Santos,Igor Campos Fontes et al.
Juliana Francisca Grossi Heleno et al.
Peritoneal fibrosis is an adverse effect of cancer therapy leading to progressive organ failure. L-Glutamine supplementation has been shown to attenuate fibrosis and improve wound healing in several types of tissue injuries. The aim of this...
Intra- and extrapulmonary lipopolysaccharides-induced acute lung injury and pharmacotherapeutic response patterns in ventilated 7-day-old rabbits [0.03%]
兔肺内和肺外脂多糖致急性肺损伤及通气条件下药物治疗反应特点的研究
Guiyin Zhuang,Qiang Gu,Siyu Xie et al.
Guiyin Zhuang et al.
We explored pharmacotherapeutic response patterns of lipopolysaccharides (LPS)-induced pneumonia and sepsis as direct and indirect acute lung injury (ALI), and efficacy of a combined surfactant (S) and inhaled nitric oxide (iNO), simulating...
The effect of short-term consumption of Bifidobacterium bifidum on the gut microbiome of obese individuals [0.03%]
双歧杆菌短期摄入对肥胖人群肠道菌群的影响
Inna Burakova,Yuliya Smirnova,Polina Morozova et al.
Inna Burakova et al.
It is known that gut microbiota dysbiosis can lead to obesity by disrupting energy consumption and metabolism. Probiotic supplements are a potential therapeutic option for improving intestinal homeostasis. The aim of this study was to inves...
The gut-retina axis in age-related macular degeneration: immune crosstalk and metabolite production [0.03%]
年龄相关性黄斑变性的肠-视网膜轴:免疫互作和代谢物产生
Beryl Zhou,Zaid Parekh,Christopher Phung et al.
Beryl Zhou et al.
Current therapies slow down advanced features but do not halt or reverse degeneration and neovascularization in dry and wet age-related macular degeneration (AMD). Recent research implicates the gastrointestinal microbiome as a potential cr...
Poliovirus receptor (PVR) expression as a predictor of relapse in colorectal cancer: bioinformatics and virtual screening [0.03%]
作为结直肠癌复发预测因子的多瘤病毒早期区域基因T抗原受体(PVR)的表达:生物信息学和虚拟筛选
Sulaiman S Alhudaithi,Muhamed Hamza R Salih,Zaid H AlHusseini et al.
Sulaiman S Alhudaithi et al.
Colorectal cancer (CRC) is one of the most frequently diagnosed malignancies worldwide. Despite advancements in CRC treatment strategies in recent years, disease recurrence remains a major problem; relapsed patients have a poorer prognosis ...
How can we balance risk and benefit of interleukin-18 armored T cell therapies? [0.03%]
如何平衡细胞疗法的危险与疗效?
Paulina Vicenova,John Maher
Paulina Vicenova
CD19-specific CAR T cells engineered to secrete a constitutively active form of the pro-inflammatory cytokine, interleukin (IL)-18 have demonstrated impressive efficacy in a recent clinical trial involving subjects who had failed prior CAR ...
Electrotherapy in the management of neuropathic corneal pain: narrative review [0.03%]
电疗法治疗神经性角膜痛:综述文章
A V Shanmathi,Mingyi Yu,Chang Liu et al.
A V Shanmathi et al.
Neuropathic corneal pain (NCP) is a debilitating condition resulting from corneal nerve damage or dysfunction, leading to persistent ocular pain, discomfort and hypersensitivity. Conventional therapy with eye drops often provides inadequate...
Expanding the clinical and genetic spectrum of RHO-associated retinitis pigmentosa [0.03%]
RHO相关色素性视网膜炎的临床和基因谱系扩展
Rebeca A S Amaral,Olivia A Zin,Rosane G Resende et al.
Rebeca A S Amaral et al.
The majority of cases of autosomal-dominant retinitis pigmentosa (adRP) are associated with rhodopsin (RHO) variants. More than 290 pathogenic variants responsible for 25%-30% of adRP cases have been identified to date. This retrospective r...
Expression of MicroRNA-155 and its associations with EBV serological markers and inflammatory cytokines in young lymphoma patients with evidence of active EBV infection [0.03%]
mir-155的表达及其与年轻淋巴瘤患者活动性ebv感染的相关自身免疫标志物及炎症细胞因子的关系研究
Lezan Medhat Mohammed,Payman S Ali,Ali Qasim Taha et al.
Lezan Medhat Mohammed et al.
The Epstein-Barr virus (EBV) is implicated in several lymphoproliferative disorders, particularly among children and adolescents who frequently experience primary EBV infection. MicroRNA-155 (miR-155), an oncogenic and immunoregulatory mole...
Observational Study
Experimental biology and medicine (Maywood, N.J.). 2026 Feb 3:251:10869. DOI:10.3389/ebm.2026.10869 2026
Integrated tear proteomics define the molecular blueprint of corneal epithelial repair [0.03%]
整合泪蛋白组学定义角膜上皮修复的分子蓝图
Nadege Feret,Marilou Decoudu,Jerome Vialaret et al.
Nadege Feret et al.
Tears are easy to collect, repeatable, and reflect the state of the corneal surface-attributes that make them attractive for bedside monitoring after surgery or injury. We performed a cross-species meta-analysis of tear proteomes from patie...