Salidroside promotes sciatic nerve regeneration following combined application epimysium conduit and Schwann cells in rats [0.03%]
牻牛儿素昔促进联合应用肌外膜导管和雪旺细胞的坐骨神经再生作用
Jiaqi Li,Yongguang Zhang,Zhimin Yang et al.
Jiaqi Li et al.
Schwann cell and nerve conduit are crucial for nerve regeneration and re-myelination after peripheral nerves injury. To investigate the effects of Salidroside on autogenous epimysium conduit mixed with BD matrigel and RSC96 Schwann cells on...
The signature of pharmaceutical sensitivity based on ctDNA mutation in eleven cancers [0.03%]
基于ctDNA突变的十一种癌症的药物敏感性标记
Shumei Zhang,Mu Su,Zhongyi Sun et al.
Shumei Zhang et al.
Gene mutations are closely related to cancers and drug sensitivity and noninvasive liquid biopsy was used to detect mutations of ctDNA in plasma. In this study, we performed exon sequencing of 416 cancer-related genes for cancer primary tis...
Molecular mechanisms of action of hesperidin in cancer: Recent trends and advancements [0.03%]
柚皮素的抗癌分子机制：最新趋势与进展
Vaishali Aggarwal,Hardeep S Tuli,Falak Thakral et al.
Vaishali Aggarwal et al.
Hesperidin belongs to flavanones class of flavonoids and is known to possess broad-spectrum applicability to prevent dreadful diseases such as cardiovascular disease, neurodegeneration, and cancer. The reported anticancer effects of hesperi...
The novel potential biomarkers for multidrug-resistance tuberculosis using UPLC-Q-TOF-MS [0.03%]
应用UPLC-Q-TOF-MS技术发现多药耐药结核病的潜在生物标志物研究
Huai Huang,Yu-Shuai Han,Jing Chen et al.
Huai Huang et al.
The lack of rapid and efficient diagnostics impedes largely the epidemic control of multidrug-resistant tuberculosis, and might misguide the therapeutic strategies as well. This study aimed to identify novel multidrug-resistant tuberculosis...
Gašper Grubelnik,Emanuela Boštjančič,Ana Pavlič et al.
Gašper Grubelnik et al.
NANOG is an important stem cell transcription factor involved in human development and cancerogenesis. Its expression is complex and regulated on different levels. Moreover, NANOG protein might regulate hundreds of target genes at the same ...
Hyperthermic intraperitoneal chemotherapy with recombinant mutant human TNF-α and raltitrexed in mice with colorectal-peritoneal carcinomatosis [0.03%]
携带肿瘤坏死因子的人TNF-α突变重组体与醛氢叶酸在结直肠癌腹膜转移小鼠模型中热化疗中的应用研究
Qianyi Gong,Changfeng Song,Xiaotong Wang et al.
Qianyi Gong et al.
Peritoneum is one of the most common metastatic sites of colorectal cancer (CRC). It has been reported that cytoreductive surgery combined with hyperthermic intraperitoneal chemotherapy (HIPEC) prolongs the lifespan of patients with periton...
Examining the association between oral health status and dementia: A nationwide nested case-controlled study [0.03%]
横断面研究：口腔健康状况与痴呆之间的关联性分析
J W Lin,C H Chang,J L Caffrey
J W Lin
Alzheimer’s disease as a consequence of chronic brain inflammation mediated by infectious microbes including the oral microbiome continues to attract support. Taiwan’s National Insurance database was used to evaluate associations between ...
Rutin promotes osteogenic differentiation of periodontal ligament stem cells through the GPR30-mediated PI3K/AKT/mTOR signaling pathway [0.03%]
rutin通过GPR30介导的PI3K/AKT/mTOR信号通路促进牙周韧带干细胞成骨分化
Bin Zhao,Yixuan Xiong,Yunpeng Zhang et al.
Bin Zhao et al.
Rutin is one of the flavonoids found in fruits and vegetables. Recent reports have revealed that rutin is a major player in proliferation and bone development. However, data on how rutin regulates the proliferation of periodontal ligament s...
Discoveries and developments of CXCR4-targeted HIV-1 entry inhibitors [0.03%]
CXCR4靶向HIV-1进入抑制剂的研究进展与发现
Chaozai Zhang,Ruohan Zhu,Qizhi Cao et al.
Chaozai Zhang et al.
The chemokine receptor CXCR4 is required for the entry of human immunodeficiency virus type 1 (HIV-1) into target cells and its expression correlates with more profound pathogenicity, rapid progression to acquired immunodeficiency syndrome ...
Quanah J Hudson,Alexandra Perricos,Rene Wenzl et al.
Quanah J Hudson et al.
Endometriosis affects up to 10% of women of childbearing age, causing symptoms that can include chronic pelvic pain and reduced fertility. The symptoms are not specific to the disease and can be confused with other gynecological conditions ...