Integrating artificial intelligence in strabismus management: current research landscape and future directions [0.03%]
人工智能在斜视管理中的应用：当前研究现状与未来方向
Dawen Wu,Xi Huang,Liang Chen et al.
Dawen Wu et al.
Advancements in artificial intelligence (AI) are transforming strabismus management through improved screening, diagnosis, and surgical planning. Deep learning has notably enhanced diagnostic accuracy and optimized surgical outcomes. Despit...
Nisrine Bissar,Rayan Kassir,Ali Salami et al.
Nisrine Bissar et al.
Alzheimer's disease (AD) is a prevalent neurodegenerative disorder characterized by progressive cognitive decline. Genetic factors have been implicated in disease susceptibility as its etiology remains multifactorial. The CD33 and the HLA-D...
Engineering ADSCs by manipulating YAP for lymphedema treatment in a mouse tail model [0.03%]
通过操纵YAP工程化ADSCs治疗小鼠尾巴淋巴水肿模型
Liru Hu,Nian Zhang,Chengzhi Zhao et al.
Liru Hu et al.
Secondary lymphedema is a chronic disease associated with deformity of limbs and dysfunction; however, conventional therapies are not curative. Adipose-derived stem cells (ADSCs) based therapy is a promising way, but a single transplantatio...
Predicting severe COVID-19 using readily available admission indicators: SpO2/FiO2 ratio, comorbidity index, and gender [0.03%]
基于入院指标预测严重COVID-19：SpO2/FiO2比率、合并症指数和性别的影响
Luan D Vu,Rebecca C Christofferson,Hollis R O&#x;Neal Jr et al.
Luan D Vu et al.
The focus of this study was to identify risk factors for severe and critical COVID-19, evaluate local respiratory immune responses to SARS-CoV-2 infection, and develop a prognostic tool for COVID-19 severity using accessible early indicator...
Neuroinflammation underlies the development of social stress induced cognitive deficit in male sickle cell mice [0.03%]
社会压力诱导的镰状细胞小鼠认知缺陷的发展与神经炎症有关
S&#x;Dravious A DeVeaux,Sofiya Vyshnya,Katherine Propsom et al.
S&#x;Dravious A DeVeaux et al.
Cognitive deficit is a debilitating complication of sickle cell disease (SCD), with a multifactorial etiopathogenesis. Here we show that neuroinflammation and dysregulation in lipidomics and transcriptomics profiles are major underlying mec...
Nada Bejar,Siyu Xiao,Dinakar Iyer et al.
Nada Bejar et al.
This review outlines some of the many approaches taken over a decade or more to repair damaged hearts. We showcase the recent breakthroughs in organ regeneration elicited by reprogramming factors OCT3/4, SOX2, KLF4, and C-MYC (OKSM). Transi...
Fuller W Bazer,Guoyao Wu,Gregory A Johnson
Fuller W Bazer
Fructose and lactate are present in high concentrations in uterine luminal fluid, fetal fluids and fetal blood of ungulates and cetaceans, but their roles have been ignored and they have been considered waste products of pregnancy. This rev...
Subunit-specific mechanisms of isoflurane-induced acute tonic inhibition in dentate gyrus granule neuron [0.03%]
异氟醚诱导的齿状回颗粒神经元急性阵挛性抑制的亚单位特异性机制
Zhiqiang Yu,Xiaodan Chen,Zheng Liu et al.
Zhiqiang Yu et al.
Prolonged exposure to volatile anesthetics may raise the risk of developing cognitive impairment by acting on gamma-a Aminobutyric acid A receptors (GABAAR). The dentate gyrus plays an important role in the hippocampus and has a high potent...
Rashadul Hasan Badhon,Atalie Carina Thompson,Jennifer I Lim et al.
Rashadul Hasan Badhon et al.
This study explores the feasibility of quantitative Optical Coherence Tomography Angiography (OCTA) features translated from OCT using generative machine learning (ML) for characterizing vascular changes in retina. A generative adversarial ...
Immunization with recombinant Streptococcus pneumoniae PgdA protects mice against lung invasion [0.03%]
肺炎链球菌重组PgdA免疫可保护小鼠免遭肺部感染入侵
Jiangming Xiao,Bichen Liu,Yibing Yin et al.
Jiangming Xiao et al.
Current pneumococcal vaccines, including the pneumococcal polysaccharide (PPV23) and conjugate (PCV13) vaccines, offer protection against specific serotypes but pose risks of serotype replacement that can alter the composition of the nasoph...