Bone quality assessment techniques: geometric, compositional, and mechanical characterization from macroscale to nanoscale [0.03%]
骨质量评估技术：从宏观到纳米尺度的几何、成分和机械表征
Heather B Hunt,Eve Donnelly
Heather B Hunt
This review presents an overview of the characterization techniques available to experimentally evaluate bone quality, defined as the geometric and material factors that contribute to fracture resistance independently of areal bone mineral ...
N Alonso,I Calero-Paniagua,J Del Pino-Montes
N Alonso
Paget's disease of bone (PDB) is the second most common metabolic bone disorder, after osteoporosis. It is characterised by focal areas of increased and disorganised bone turnover, coupled with increased bone formation. This disease usually...
Shaocheng Ma,Oliver Boughton,Angelo Karunaratne et al.
Shaocheng Ma et al.
Bone is a complex hierarchical structure, and its principal function is to resist mechanical forces and fracture. Bone strength depends not only on the quantity of bone tissue but also on the shape and hierarchical structure. The hierarchic...
Locomotive Syndrome: Operational Definition Based on a Questionnaire, and Exercise Interventions on Mobility Dysfunction in Elderly People [0.03%]
基于问卷的“机车症状”的操作性定义及其运动干预改善老年人行动不便的交叉试验研究
M Akai,T Doi,A Seichi et al.
M Akai et al.
The increasing elderly population has a great impact on public health, and it is important to understand the progression of musculoskeletal disorders seen in this population. To establish useful preventative methods for such locomotive diso...
Epidemiology of Locomotive Organ Disorders and Symptoms: An Estimation Using the Population-Based Cohorts in Japan [0.03%]
基于日本人口队列的运动器官障碍和症状流行病学评估研究
Noriko Yoshimura,Kozo Nakamura
Noriko Yoshimura
Although locomotive organ diseases such as osteoporotic fractures and osteoarthritis are major reasons for disability and require support, little information is available regarding the epidemiology of musculoskeletal dysfunction and its sym...
Kozo Nakamura,Toru Ogata
Kozo Nakamura
Locomotive syndrome is a condition of reduced mobility due to impairment of locomotive organs. Since upright bipedal walking involves minutely controlled movement patterns, impairment of any aspect of the locomotive organs has the potential...
Robert D Blank
Robert D Blank
Bone and muscle mass are highly correlated. In part, this is a consequence of both tissues sharing common genetic determinants. In addition, both tissues are responsive to their mechanical environments. New genetic tools in mice will allow ...
Adrian Vella,Rajiv Kumar
Adrian Vella
Uncarboxylated osteocalcin enhances insulin and adiponectin release and improves glucose tolerance in mice. Data in humans do not unequivocally support a role for osteocalcin in glucose homeostasis. Changes in the amount of uncarboxylated o...
Physiology of Mechanotransduction: How Do Muscle and Bone "Talk" to One Another? [0.03%]
力学信号转导的生理学：肌肉和骨骼如何“相互交流”？
Janalee Isaacson,Marco Brotto
Janalee Isaacson
The complexity of cell interactions with their microenvironment and their ability to communicate at the autocrine, paracrine, and endocrine levels has gradually but significantly evolved in the last three decades. The musculoskeletal system...
Ann Prentice,Inez Schoenmakers,Kerry S Jones et al.
Ann Prentice et al.
Africa is heterogeneous in latitude, geography, climate, food availability, religious and cultural practices, and skin pigmentation. It is expected, therefore, that prevalence of vitamin D deficiency varies widely, in line with influences o...