Lily Kaufman,Lilia Valentic,Hannah Moulton et al.
Lily Kaufman et al.
Cancer-related alopecia (CRA) presents a significant challenge for many patients undergoing cancer treatment, often affecting their psychological well-being and sense of identity. In my opinion, the optimal management of CRA requires a proa...
The Role of Cetuximab in Non-Melanoma Skin Cancer: A Review of Clinical Evidence and Emerging Strategies [0.03%]
西妥昔单抗在非黑色素瘤皮肤癌中的作用：临床证据与新兴策略综述
Imperia Nuzzolese,Stefano Cavalieri,Lisa F Licitra et al.
Imperia Nuzzolese et al.
Non-melanoma skin cancers (NMSCs), particularly basal cell carcinoma (BCC) and cutaneous squamous cell carcinoma (cSCC), are the most common malignancies in the Caucasian population. While localized disease has a high cure rate, advanced ca...
Interrupted Systemic Therapy (Drug Holiday) for Metastatic Sarcoma: Is It Safe? [0.03%]
转移性肉瘤系统治疗中断（药物假期）安全吗？
Alessandra Maleddu,Cole Wayant
Alessandra Maleddu
Sarcomas are a diverse group of rare, mesenchymal tumors that vary in terms of clinical behavior, aggressiveness, and responsiveness to treatment. The management of metastatic sarcoma is challenging and requires a multidisciplinary approach...
Kia Lor,Eva Kubrova,Ryan S D&#x;Souza et al.
Kia Lor et al.
Danh D Truong,Roberto Cardenas-Zuniga,Joseph A Ludwig
Danh D Truong
Desmoplastic small round cell tumor (DSRCT) is an aggressive soft-tissue sarcoma driven by the EWSR1::WT1 fusion protein resulting from a chromosomal translocation between the EWSR1 (Ewing sarcoma breakpoint region 1) gene on chromosome 22 ...
The Evolving Landscape of Ovarian Cancer: Innovations in Biotechnology and Artificial Intelligence- Based Screening and Treatment [0.03%]
卵巢癌的演变景观：生物技术和基于人工智能的筛查和治疗创新
Revathi Unni K,Amrisa Pavithra Elango,Roobanayaki Subramanian et al.
Revathi Unni K et al.
Ovarian Cancer (OC) is a serious health problem that affects a great number of women globally. It is still one of the deadliest gynecological cancers due to restricted treatment choices and late-stage diagnosis. Worldwide, OC ranks as the s...
Kevin Yang,Hoang Ho-Pham,Collin Pieper et al.
Kevin Yang et al.
Vismodegib is a hedgehog inhibitor used in the treatment of basal cell carcinomas and basal cell nevus syndrome. However, treatment is associated with significant side effects that can impact compliance, including fatigue, muscle cramps, ha...
Unmasking the Rare but Lethal Cardiac Complications of Immune Checkpoint Inhibitor Therapy: A Review of Mechanisms, Risk Factors, and Management Strategies [0.03%]
揭开免疫检查点抑制剂治疗罕见但致命的心脏并发症的面纱：机制、危险因素和管理策略综述
Laudy Chehade,Noura Abbas,Kristel Dagher et al.
Laudy Chehade et al.
Immune checkpoint inhibitors (ICIs) have revolutionized cancer treatment by enabling the immune system to effectively target and destroy cancer cells. While ICIs offer significant survival benefits across various malignancies, their use is ...
Nanomedicine-Based Treatments for Rare and Aggressive Ocular Cancers: Advances in Drug Delivery [0.03%]
基于纳米药物的罕见和侵袭性眼部癌症治疗：药物递送新进展
Devesh U Kapoor,Geeta Patel,Bhupendra G Prajapati
Devesh U Kapoor
Ocular cancers, though rare, present significant therapeutic challenges due to their aggressive nature, high metastatic potential and anatomical constraints that limit drug delivery. Conventional therapies, including radiation, enucleation,...
Targeted Therapy and Immunotherapy in Elderly Patients with Metastatic Colorectal Cancer [0.03%]
老年人转移性结直肠癌的靶向治疗和免疫治疗
Wenjie Huang,Yunpeng Liu
Wenjie Huang
At initial diagnosis, over half of the patients with metastatic colorectal cancer (mCRC) are aged 65 years or older. In this population, age-related declines in organ reserve and the presence of comorbidities can significantly weaken drug t...