Recent Advances in Neoadjuvant Treatment of Anaplastic Thyroid Carcinoma: A Narrative Review [0.03%]
分化型甲状腺癌新辅助治疗近期研究进展：叙事综述
Juncong Fan,Yeqin Ni,Rong Ni et al.
Juncong Fan et al.
Anaplastic thyroid carcinoma (ATC) is a highly aggressive malignancy characterized by rapid progression, restricted therapeutic options, and dismal prognosis. Conventional therapeutic modalities demonstrate limited efficacy, especially for ...
The Immunological Landscape of the Tumor Microenvironment: Implications for Immunotherapy of Unresectable and Metastatic Soft Tissue Sarcomas [0.03%]
肿瘤微环境的免疫特征及其对不可切除和转移性软组织肉瘤免疫治疗的影响
Simo Zou,Ang Li,Shiqi Yang et al.
Simo Zou et al.
The field of immunotherapy for unresectable soft tissue sarcomas (STS) is transitioning from a one-size-fits-all approach toward a precision immuno-oncology paradigm. The pronounced immunological heterogeneity among histological subtypes an...
Oncofertility in the Age of HER2 Blockade, Immunotherapy, PARP inhibitors, CDK4/6 inhibitors and Endocrine Treatment: Unanswered Questions in Breast Cancer [0.03%]
HER2抑制、免疫治疗、PARP抑制剂、CDK4/6抑制剂和内分泌治疗时代的肿瘤生殖医学：乳腺癌未解之谜
Karolina Weiner-Gorzel,Lynda McSorley,Janice M Walshe
Karolina Weiner-Gorzel
As survival among reproductive-age patients with breast cancer continues to improve with modern therapies, concerns regarding fertility preservation, gonadotoxicity, and pregnancy safety have become increasingly prominent. Fertility conside...
Emerging Applications of CAR-T Cell Therapy in Overcoming Resistance and Expanding Targets in Hematologic Malignancies: Insights from Recent Research [0.03%]
CAR-T细胞治疗在克服血液系统恶性肿瘤耐药性和扩大靶点的新兴应用：近期研究见解
Iraj Alipourfard,Zahra Shafaghat,Saber Saharkhiz et al.
Iraj Alipourfard et al.
Chimeric antigen receptor T-cell (CAR-T) therapy has revolutionized the treatment outcomes of patients with hematologic malignancies, including B-cell acute lymphoblastic leukemia (B-ALL), diffuse large B-cell lymphoma (DLBCL), and multiple...
Breakthroughs in HBV-related HCC Therapy: The Unmatched Potential of Immune Checkpoint Inhibitors [0.03%]
乙肝相关肝癌治疗的进展：免疫检查点抑制剂的不可替代性
Chenlu Liu,Le Chang,Ying Yan et al.
Chenlu Liu et al.
Immune checkpoint inhibitors have reshaped the therapeutic landscape of hepatocellular carcinoma by restoring T cell-mediated antitumor immunity. However, the clinical benefit of monotherapy remains limited, highlighting the need for improv...
Hemithorax Irradiation for High-Risk Chest Wall Sarcomas: Current Evidence, Clinical Practice and Future Directions [0.03%]
半侧胸壁照射治疗高危胸部恶性肉瘤：现有证据、临床实践及未来方向
YuanYou Yang,Xin Sun,Jie Xu et al.
YuanYou Yang et al.
Opinion statement: Hemithorax irradiation (HT‑RT) is a cornerstone multimodal treatment for high‑risk chest wall bone and soft tissue sarcomas, particularly Ewing sarcoma in children and young adults. Current non‑rando...
Georgios M Stergiopoulos,Gabriel Tinoco,Steven I Robinson
Georgios M Stergiopoulos
Solitary fibrous tumor (SFT) is an exceedingly rare mesenchymal neoplasm classified as a soft tissue sarcoma (STS). While historically considered indolent, up to 50% of cases can recur or metastasize after long-term follow-up. Complete surg...
Addressing Unmet Needs in the Management of Small Cell Lung Cancer: Treatment of Brain Metastases, Quality of Life, and the Role of Real-World Evidence [0.03%]
小细胞肺癌未满足需求的治疗策略：脑转移、生存质量及真实世界证据的作用
Yunfei Dai,Jing Fei
Yunfei Dai
Small cell lung cancer (SCLC) is a highly aggressive neuroendocrine tumor. Although patient survival has been significantly improved by immune checkpoint inhibitors combined with chemotherapy, three major unmet needs remain in SCLC manageme...
Imaging Strategies and Research Advances in Gastrointestinal Stromal Tumors [0.03%]
胃肠道间质瘤的影像策略和研究进展
Dongxiao Yang,Guanghui Yu
Dongxiao Yang
Advances in Pharmacologic- and Non-pharmacologic Interventions for Cancer Pain: A Narrative Review [0.03%]
癌症疼痛的药理和非药理干预进展：综述性文章
Shulin Wang,Jingyu Yao,Qiuli Wang et al.
Shulin Wang et al.