Paolo Strati,Sattva S Neelapu
Paolo Strati
Purpose of review: Chimeric antigen receptor (CAR) T cells are a form of adoptive therapy employing autologous T cells engineered with an artificial receptor, able to recognize tumor antigens through an HLA-independent me...
Kyuwan Lee,Laura Kruper,Christina M Dieli-Conwright et al.
Kyuwan Lee et al.
Purpose of review: Obesity is a recognized risk factor for the development of breast cancer and recurrence even when patients are treated appropriately. We reviewed the literature that addresses the impact of obesity on d...
Ashley E Aaroe,Kathryn S Nevel
Ashley E Aaroe
Purpose of review: Peripheral natural killer (NK) and T cell neoplasms comprise approximately 10-15% of non-Hodgkin lymphomas. There are 27 different subtypes of peripheral NK and T cell neoplasms, each of which is relati...
Immune Checkpoint Inhibitors in Acute Myeloid Leukemia: Novel Combinations and Therapeutic Targets [0.03%]
急性髓系白血病的免疫检查点抑制剂：新的联合疗法和治疗靶点
Maximilian Stahl,Aaron D Goldberg
Maximilian Stahl
Purpose of review: Immune checkpoint therapy has dramatically changed the therapeutic landscape of solid malignancies. Here, we review the scientific rationale and current data evaluating immune checkpoint inhibitors in a...
Targeting Barriers of Systems of Care in a Growing Multi-disciplinary Field [0.03%]
针对照护系统中的障碍物 在一个日益发展的跨学科领域中定位
Tolulope A Agunbiade,Yvonne Ottaviano,Debolina Goswami et al.
Tolulope A Agunbiade et al.
Purpose of review: Cardio-oncology is a growing multi-disciplinary field that focuses on treating and preventing cardiovascular complications in cancer survivors and patients. This review summarizes the current clinical n...
Updates on Hematologic Malignancies in the Older Adult: Focus on Acute Myeloid Leukemia, Chronic Lymphocytic Leukemia, and Multiple Myeloma [0.03%]
老年血液系统恶性肿瘤的最新研究进展：以急性髓系白血病、慢性淋巴细胞白血病和多发性骨髓瘤为重点
Li-Wen Huang,Sandy W Wong,Charalambos Andreadis et al.
Li-Wen Huang et al.
Purpose of review: Hematologic malignancies are common and difficult to treat in older adults. In this review, we focus on recent updates in diseases with several novel agents relevant to older adults-acute myeloid leukem...
Current Status and Future Directions of Immunotherapy in Renal Cell Carcinoma [0.03%]
肾细胞癌免疫治疗的现状与未来方向
Bryden Considine,Michael E Hurwitz
Bryden Considine
Purpose of review: Renal cell carcinoma (RCC) was recognized as an immunologically sensitive cancer over 30 years ago. The first therapies to affect the course of RCC were cytokines (interferon alfa-2B and interleukin-2)....
Jason Chua,Elizabeth Nafziger,Denise Leung
Jason Chua
Purpose of review: Temozolomide is a first-line treatment for newly diagnosed glioblastoma. In this review, we will examine the use of temozolomide in other contexts for treating gliomas, including recurrent glioblastoma,...
Clayton P Smith,Anna Laucis,Stephanie Harmon et al.
Clayton P Smith et al.
Purpose of review: This review aims to highlight the limitations of current standard-of-care prostate cancer (PCa) imaging and discuss novel clinical imaging in advanced disease. ...
Cardiovascular Complications Associated with Multiple Myeloma Therapies: Incidence, Pathophysiology, and Management [0.03%]
与多发性骨髓瘤治疗相关的心血管并发症：发生率、病理生理和管理
Vivek G Patel,Robert F Cornell
Vivek G Patel
Purpose of review: Multiple myeloma is a common hematologic malignancy characterized by recurrent relapsing disease course requiring use of various therapies. Over the past few decades, significant advancements in the tre...