Letter: Advances in Radiotherapy for Soft Tissue Sarcomas in 2025: A Review [0.03%]
2025年软组织肉瘤放射治疗进展:综述论文
G F Foppele,R L M Haas,L M Wiltink
G F Foppele
Immunotherapy Resistance in Pancreatic Ductal Adenocarcinoma: from Tumor Biology to Biomarker-Guided Strategies [0.03%]
胰腺导管腺癌免疫治疗抵抗:从肿瘤生物学导向生物标志物指导策略
Layal Al Mahmasani,Mohamad Mourad,Noura Abbas et al.
Layal Al Mahmasani et al.
Purpose of review: Despite major advances inimmunotherapy, pancreatic ductal adenocarcinoma (PDAC) remains one of the most immunotherapy-resistant solid tumors. This review aims to summarize the key biological mechanisms ...
The Application and Advancement of Herbal Medicine in Gastrointestinal Cancers: A Bibliometrix Visualization and Pan-cancer Analysis [0.03%]
基于Bibliometrix可视化的中草药在消化道肿瘤应用及展望:泛癌分析视角
Lingyun Zhao,Heng Wang,Yuchen Jiang et al.
Lingyun Zhao et al.
Introduction: Herbal medicine has emerged as an important area of investigation in gastrointestinal cancers owing to its multitarget therapeutic potential and growing integration with modern oncology. However, the rapid e...
Follicular Lymphoma: Novel Therapies and Strategies for Optimal Therapeutic Sequencing [0.03%]
新型疗法和治疗顺序策略在滤泡性淋巴瘤中的应用
Rodrigo Fonseca,Talal Hilal
Rodrigo Fonseca
Purpose of review: Follicular lymphoma (FL) is the most common indolent non-Hodgkin lymphoma, characterized by a relapsing and remitting course and a median overall survival exceeding 15-20 years with modern therapy. Whil...
DNA Repair, Epigenetic Dysregulation, and Cytokine Network Crosstalk in Head and Neck Cancer: Emerging Therapeutic Opportunities and Clinical Trials [0.03%]
头颈鳞癌中表观遗传与免疫逃逸:机制探索和临床试验
Nistha Agarwal,Garima Sharma,Ashish Ranjan Sharma et al.
Nistha Agarwal et al.
Purpose of review: Head and neck cancer (HNC) is characterized by profound genomic instability, therapeutic resistance, and suboptimal survival outcomes, particularly in advanced-stage disease. This review aims to critica...
From Symptom Control to Precision Supportive Oncology: Integrating Artificial Intelligence in Supportive Oncology for Gastrointestinal Cancers [0.03%]
从症状控制到精准支持性肿瘤学:人工智能在胃肠癌症支持性肿瘤学中的整合应用
Arunkumar Krishnan,Mellar P Davis,Kunal C Kadakia
Arunkumar Krishnan
Purpose of review: Gastrointestinal (GI) cancers are among the most common malignancies worldwide and impose a substantial symptom burden from diagnosis through survivorship. Despite advances in systemic therapies and sur...
Infectious Complications of Antibody-Drug Conjugates: A Review of Safety Data from FDA-Approved Agents [0.03%]
抗体偶联药物的感染并发症:FDA批准药物安全数据的回顾分析
Georgios Schinas,Pantazis-Michael Voutsinas,Dimitra Stefanou et al.
Georgios Schinas et al.
Purpose of review: With fifteen agents now FDA-approved and indications expanding into earlier treatment lines, antibody-drug conjugates (ADCs) represent a rapidly growing class of targeted cancer therapeutics. Despite th...
Next-Generation Checkpoint Combinations: Optimizing PD-(L)1-Based Therapy Across the Advanced, Adjuvant, and Neoadjuvant Settings [0.03%]
下一代免疫治疗联合方案:在晚期、辅助和新辅助设置中优化PD-(L)1-based疗法
Fausto Petrelli,Lara Colombo Zefinetti,Andrea DAlessio et al.
Fausto Petrelli et al.
Purpose of review: Programmed cell death 1 (PD-1) and programmed death ligand 1 (PD-L1) inhibitors are foundational components of therapy across many solid tumors, yet primary and acquired resistance limit durable benefit...
Revisiting the Immunological Landscape of Locoregional Therapies for Gastrointestinal Cancers: A Shift Toward Interventional Immuno-Oncology [0.03%]
胃肠道肿瘤局部区域治疗的免疫微环境:向干预性免疫肿瘤学转变
Augustin Suffisseau,Johanne Seguin,Katia Lemdani et al.
Augustin Suffisseau et al.
Purpose of review: Locoregional therapies have emerged as key components in the therapeutic arsenal against gastrointestinal cancers, offering minimally invasive options with curative potential. Beyond their direct cytoto...
Claudia Trojaniello,Antonella Lucia Marretta,Bianca Arianna Facchini et al.
Claudia Trojaniello et al.
Purpose of review: The advent of anti-PD-1 therapy has transformed the treatment paradigm of advanced melanoma, enabling durable responses in a proportion of patients. However, the impact of both primary and acquired resi...