K P Minneman
K P Minneman
G protein-coupled receptors (GPCRs) are encoded by a vast gene superfamily, reflecting the large number of ligands that must be specifically recognized at any given cell surface. The discovery that the variety of GPCRs is further expanded t...
Potassium channel subunits encoded by the KCNE gene family: physiology and pathophysiology of the MinK-related peptides (MiRPs) [0.03%]
由钾通道基因家族KCNE编码的通道亚单位：与MinK相关的肽（MiRP）的生理和病理生理学
G W Abbott,S A Goldstein
G W Abbott
Voltage-gated potassium channels provide tightly Controlled, ion-specific pathways across membranes and are key to the normal function of nerves muscles. They arise from the assembly of four pore-forming proteins called alpha-subunits. To a...
J W Putney Jr
J W Putney Jr
The versatility of Ca(2+) as a messenger in multiple signaling events requires that the concentration of calcium ions within the cytoplasm be highly regulated. In particular, the release of calcium from intracellular stores must often be li...
Common to both academia and industry: the challenge of discovery. An interview with Perry Molinoff [0.03%]
学术界和工业界的共同点：探索的挑战。对Perry Molinoff的采访
P B Molinoff
P B Molinoff
Perry Molinoff recognizes the distinctions between basic and applied science, between academic and industrial research, and between the preclinical and clinical realities of drug development. But he generally discusses these categories in f...
R J Huxtable
R J Huxtable