Small Bowel Adenocarcinoma Frequently Exhibits Lynch Syndrome-associated Mismatch Repair Protein Deficiency But Does Not Harbor Sporadic MLH1 Deficiency [0.03%]
小肠腺癌经常出现林奇综合征相关的错配修复蛋白缺陷但不伴发散发性MLH1缺陷
Michelle Xia,Aatur D Singhi,Beth Dudley et al.
Michelle Xia et al.
Universal screening for Lynch syndrome has been advocated for colorectal carcinoma but its utility in small bowel adenocarcinoma has not been reported. We analyzed a consecutive series of 71 small bowel adenocarcinomas identified over an 8-...
The Role of SATB2 as a Diagnostic Marker of Sinonasal Intestinal-type Adenocarcinoma [0.03%]
SATB2作为鼻窦分肠型腺癌诊断标志物的作用研究
Alena Skalova,Aylin Sar,Jan Laco et al.
Alena Skalova et al.
Background: Intestinal-type adenocarcinoma (ITAC) of the nasal cavity and paranasal sinuses is an uncommon tumor associated with exposure to wood and leather dust, nickel, and possibly smoking. ITAC shares phenotypical fe...
Adriana Handra-Luca,Frederique Tissier
Adriana Handra-Luca
Fluorescent Immunohistochemistry: An Important Tool to Reveal Proteins From Tissues in Ancient Mummified Remains [0.03%]
荧光免疫组化技术——揭示古代木乃伊组织中蛋白质的重要工具
Daniela Chessa,Paola Delaconi,Nikki Kelvin et al.
Daniela Chessa et al.
During the restoration of the Saint Antonio Abate Cathedral in Castelsardo, Sardinia, Italy, numerous human remains were found in a crypt. The burial site contained upwards of 120 individuals organized in successive layers from the bottom o...
Usage of DNA Fingerprinting Technology for Quality Control in Molecular Lab Bench Work [0.03%]
DNA指纹技术在分子实验台工作质量控制中的应用
Linda Y McIntosh,Janella E Lal,Dahui Qin
Linda Y McIntosh
One of the major quality assurance (QA) goals in many molecular laboratories is to avoid sample pipetting errors on the lab bench; especially when pipetting into multiwell plates. A pipetting error can cause a switch in patient samples, whi...
Immunohistochemical Expression of Podoplanin in Clinical Variants of Oral Leukoplakia and Its Correlation With Epithelial Dysplasia [0.03%]
临床口腔黏膜白斑亚型中Podoplanin的表达及其与上皮不典型增生的相关性研究
Brendan D&#x;souza,Ramakant Nayak,Vijayalakshmi S Kotrashetti
Brendan D&#x;souza
Oral leukoplakia is the most common premalignant lesion of the oral cavity and is associated with development of oral squamous cell carcinoma. Certain changes at cellular and molecular level are important indicators for transformation into ...
HER2 Status in Gastroesophageal Adenocarcinomas: Correlation Between Immunohistochemistry and Fluorescence In Situ Hybridization Methodologies [0.03%]
胃食管腺癌的HER2状态：免疫组化与荧光原位杂交方法的相关性研究
Scott A Robertson,Ashley Cimino-Mathews,Toby C Cornish
Scott A Robertson
Semiquantitative immunohistochemistry (IHC) is commonly used in combination with fluorescence in situ hybridization (FISH) to detect HER2 amplification in gastroesophageal adenocarcinomas. Most laboratories apply these tests in a sequential...
Is SP174 Immunohistochemistry an Interesting Ancillary Tool to Determine RAS Mutational Status in Colorectal Carcinoma? [0.03%]
SP174免疫组化能否成为判断结直肠癌RAS突变状态的有价值的辅助手段？
Arnaud Uguen,Paul Gueguen,Briac Guibourg et al.
Arnaud Uguen et al.