+Clinicopathologic Features Of Warthin-Like Subtype Of Papillary Thyroid Carcinoma [0.03%]
类似Warthin型乳头状甲状腺癌的临床病理特征
Lixin Wang,Depeng Hu,Bugao Guan et al.
Lixin Wang et al.
This study aimed to explore the clinicopathological characteristics, immunophenotype, histologic occurrence, diagnosis, and differential diagnosis of the Warthin-like variant of papillary thyroid carcinoma. The clinical features, thyroid fi...
HER2 In Situ Hybridization: Validation and Implementation of Brightfield Assay in a US Academic Pathology Laboratory [0.03%]
原位杂交测定HER2基因扩增的产品验证及在美国一所医学院病理实验室的应用实施
Megan L Troxell,Alex M Dussaq,Joanna Solarewicz et al.
Megan L Troxell et al.
Assessment of HER2 overexpression and gene (ERBB2) amplification remains an essential predictive test that determines tailored breast cancer therapy. Based on institutional needs, we recently validated the VENTANA HER2 Dual ISH DNA Probe Co...
Keratoameloblastoma of the Jaw Bones: Description of 2 Rare Cases and Cytokeratin Profile [0.03%]
下颌骨角化牙胶瘤两例报告及细胞角蛋白谱型分析
Felipe Barreto Lemos,Paulo Tambasco De Oliveira,Flávia Caló de Aquino Xavier et al.
Felipe Barreto Lemos et al.
Keratoameloblastoma is a rare keratinizing neoplasia characterized by ameloblastic differentiation, which histopathologically resembles an odontogenic keratocyst. In view of its expansive growth, surgical enucleation and resection are alter...
Role of Twist and Vimentin as Epithelial-Mesenchymal Transition Biomarkers in Oral Squamous Cell Carcinoma: Relation to Cancer-Associated Fibroblasts [0.03%]
TWIST和VIMENTIN作为口腔鳞癌上皮间质转化生物标志物的作用与癌症相关成纤维细胞的关系研究
Eman Kh Allam,Hamdy A-M Metwaly,Eman M E-D Megahed et al.
Eman Kh Allam et al.
Various molecular pathways regulate oral squamous cell carcinoma (OSCC) progression, including epithelial-mesenchymal transition (EMT), which involves loss of epithelial adhesion, acquisition of mesenchymal traits, and upregulation of marke...
Exploring the Immune Microenvironment for Predicting Immunotherapy Efficacy in Epstein-Barr Virus-Associated Gastric Cancer [0.03%]
探究免疫微环境在预测EB病毒相关胃癌免疫治疗疗效中的作用
Yunjoo Cho,Sung Hee Lim,Seung Tae Kim et al.
Yunjoo Cho et al.
Epstein-Barr virus-associated gastric cancer (EBVaGC) represents an immunogenic subtype of gastric cancer. However, the effectiveness of anti-PD1 agents in EBVaGC remains uncertain, and reliable predictive biomarkers are currently unavailab...
Integrating Clinical and Molecular Insights: CTPS1 as a Key Biomarker of Tumor Progression and Prognosis in Colorectal Adenocarcinoma [0.03%]
临床和分子特征整合：CTPS1是结直肠腺癌进展及预后的关键生物标志物
Dina Moustafa Thabit,Rofida Khalifa,Dalia M Thabet
Dina Moustafa Thabit
Colorectal cancer (CRC) remains a leading cause of global cancer-related mortality. Cytidine triphosphate synthase 1 (CTPS1) is an essential enzyme for DNA synthesis and cell cycle progression. While CTPS1 has been implicated in the pathoge...
Renal Cell Carcinoma With Concurrent Loss of SMARCB1/INI-1 and Fumarate Hydratase By Immunohistochemistry: A Case Report With Review of the Literature [0.03%]
免疫组织化学共丢失SMARCB1/INI-1和苹果酸脱氢酶的肾细胞癌一例报告及文献复习
Huili Li,Ezra Baraban,Pedram Argani et al.
Huili Li et al.
Both SMARCB1(INI-1)-deficient and FH (fumarate hydratase)-deficient renal cell carcinoma (RCC) have a male predominance, potentially overlapping high-grade histologic features, and typically poor clinical outcomes. SMARCB1(INI-1) deficiency...
A Tissue Processing Technique for Improving Slide Preparation Quality of ESD Specimens [0.03%]
一种改进ESD标本切片制作质量的组织处理技术
Shanshan Huang,Xiaodan Fu,Yu Zhang et al.
Shanshan Huang et al.
Background: The efficacy of endoscopic submucosal dissection (ESD) procedures and subsequent treatment is predominantly reliant on precise pathologic evaluation, intricately linked to specimen sampling and paraffin sectio...
Solving the Puzzle of Hans' Algorithm (HA) Methodological Shortcomings: Canadian Harmonization of Hans' Algorithm for Diffuse Large B-Cell Lymphoma (DLBCL) and Development of Fit-for-Purpose Modified Hans' Algorithm (mHA) [0.03%]
汉斯算法（HA）方法学缺陷的破解：加拿大弥漫性大B细胞淋巴瘤（DLBCL）的汉斯算法和谐化及改良汉斯算法（mHA）的开发
Emina Torlakovic,Ariz Akhter,Allam Shawwa et al.
Emina Torlakovic et al.
Hans' algorithm (HA) is the most frequently used surrogate biomarker scheme for subtyping Diffuse large B-cell lymphoma (DLBCL) by the cell-of-origin (COO) into GCB and non-GCB subtypes. The originally published positive and negative predic...