Telomerase Immunocytochemistry in Lymphocytes From Chronic Lymphocytic Leukemia [0.03%]
慢性淋巴细胞白血病淋巴细胞端粒酶的免疫细胞化学检测
Mirna Sučić,Nives Ljubić,Dubravka Županić Krmek
Mirna Sučić
Human telomerase reverse transcriptase (hTERT) is detectable in normal progenitor cells, tumor cells, and B-cell chronic lymphocytic leukemia (B-CLL) cells. hTERT expression, in addition to other prognostic factors, is reportedly associated...
Correlation of MammaPrint to Histopathologic Variables and Comparison to Magee Equations in Adjuvant and Neoadjuvant Cohorts of Estrogen-Receptor Positive HER2-Negative Breast Carcinoma [0.03%]
MammaPrint与ER阳性HER2阴性乳腺癌的组织病理学变量的相关性和在辅助和新辅助队列中与Magee等式比较研究
Mariel Bedell,Tatiana M Villatoro,Stephanie N David et al.
Mariel Bedell et al.
MammaPrint (MP) is a multigene assay utilized for prognostic and predictive use in early stage ER+/HER2-negative breast cancer (BC). There is limited data on MP correlation to histopathologic variables, including multivariable model Magee E...
Differential Expression Patterns of Bcl-2, D2-40, β-Katenin, and E-Cadherin in Thymomas: Correlation With Clinical Stages and Subtypes [0.03%]
Bcl-2、D2-40、β-Katenin和E-钙黏着蛋白在胸腺瘤中差异表达模式及其与临床分期及亚型的关系
Busra Yaprak Bayrak,Aysegul U Kefeli,Cigdem Vural et al.
Busra Yaprak Bayrak et al.
Thymomas are rare mediastinal tumors exhibiting heterogeneous behavior. Although histologic subtypes and stages serve as prognostic factors, the molecular mechanisms of thymoma progression are unclear. Immunohistochemical markers like Bcl-2...
Coilin Is Not Expressed by Immunohistochemistry in Hodgkin and Diffuse Large B-cell Lymphomas [0.03%]
Coilin在霍奇金淋巴瘤和弥漫性大B细胞淋巴瘤中免疫组化检测为阴性
Georgia Karpathiou,Mousa Mobarki,Shaqraa Musawi et al.
Georgia Karpathiou et al.
Coilin is the signature protein of Cajal bodies (CBs), membrane-less organelles probably acting as sites for post-transcriptional RNA modification. Recent data suggest that coilin may be a regulator of the NF-kB activity, and Hodgkin lympho...
P53 Puzzle: WWP1 and PARC Immunohistochemistry Illuminate New Pathways for Serous Ovarian Cancer [0.03%]
p53难题：WWP1和PARCb免疫组化揭示浆液性卵巢癌的新途径
Elif Ozsagir,Mustafa E Ercin,Figen Celep Eyuboglu et al.
Elif Ozsagir et al.
High-grade serous carcinoma is categorized based on p53 mutation status. A relationship is known to exist between p53 mutations and p53 immunoexpression patterns, including overexpression, complete absence, cytoplasmic, and wild-type patter...
TAGLN2-mediated Actin Cytoskeleton Stabilization Promotes Proliferation and Metastasis of Ovarian Carcinoma [0.03%]
TAGLN2介导的细胞骨架活化蛋白促进卵巢癌增殖和转移
Xiaoxiao Qiu,Mengting Jiang,Haiyan Qu et al.
Xiaoxiao Qiu et al.
Transgelin-2 (TAGLN2) is an actin-binding protein associated with tumor progression, particularly in gastric and brain tumors. However, its role in ovarian cancer metastasis is still not fully understood. This study investigated the role of...
Expression of EZH2 and Fatty Acid Synthase in Breast Tissues From Healthy Women With Breast Cancer Risk Factors [0.03%]
携带乳腺癌危险因素的健康妇女乳腺组织中EZH2和脂肪合成酶的表达
Katelyn Zebrowski,Kaleb June,Dafydd Thomas et al.
Katelyn Zebrowski et al.
Tissue-based biomarkers that identify women with increased breast cancer risk are needed for cancer prevention. Enhancer of zeste 2 (EZH2) and fatty acid synthase (FASN) are associated with breast cancer aggressiveness, but their expression...
Toward Accurate Deep Learning-Based Prediction of Ki67, ER, PR, and HER2 Status From H&E-Stained Breast Cancer Images [0.03%]
通过H&E染色的乳腺癌图像精确预测Ki67、ER、PR和HER2状态的深度学习方法研究
Amir Akbarnejad,Nilanjan Ray,Penny J Barnes et al.
Amir Akbarnejad et al.
Despite improvements in machine learning algorithms applied to digital pathology, only moderate accuracy, to predict molecular information from histology alone, has been achieved so far. One of the obstacles is the lack of large data sets t...
Genetic and Epigenetic Changes in Melanoma Progression: A TCGA-based Study [0.03%]
黑色素瘤进展中的遗传和表观遗传变化：一项基于TCGA的研究
Yasemin Cakir,Banu Lebe,M Hasan Toper et al.
Yasemin Cakir et al.
We aimed to investigate molecular mechanisms affecting melanoma progression by comparing genetic/epigenetic features between melanomas of different Breslow thickness and stage using TCGA (The Cancer Genome Atlas) data. The TCGA, Firehose Le...