Prognostic Significance of C-MYC and EGFR Overexpression in Gastrointestinal Stromal Tumors: An Immunohistochemical Study [0.03%]
C-MYC和EGFR过度表达在胃肠道间质瘤中的预后价值：免疫组化研究
Sarra Ben Rejeb,Dorra Aloui,Asma Ayari et al.
Sarra Ben Rejeb et al.
Introduction: In addition to mutations in KIT and PDGFRA, many other genetic alterations have been described in gastrointestinal stromal tumors (GISTs), including amplifications of C-MYC and EGFR, which are often associat...
The Prognostic Impact of SIRT1, STAT3, and YAP1 in Colorectal Carcinoma [0.03%]
SIRT1、STAT3和YAP1在结直肠癌预后中的作用
Shimaa Elkholy,Aya Abdelbary,Dina Elazab et al.
Shimaa Elkholy et al.
Colorectal cancer (CRC) is the most common gastrointestinal malignancy with a complicated behavior including relapse, metastasis, and development of resistance to chemotherapeutic drugs. Silent information regulator 2 homologue 1 (SIRT1), s...
Low Expression of Mitochondrial Ribosomal Protein S5 is Associated With Poor Prognosis in Patients With Clear Cell Renal Cell Carcinoma [0.03%]
线粒体核糖体蛋白S5低表达与透明细胞肾细胞癌患者预后不良有关
Xiaoxiao Yang,Bo Han,Qian Xie et al.
Xiaoxiao Yang et al.
Mitochondrial ribosomal protein S5 (MRPS5) is abnormally expressed in various tumor tissues and may be a key molecule for the regulation of tumors. Our aim is to investigate the relationship between the expression of MRPS5 in clear cell ren...
New Approach in the Interpretation of Complex Triple-negative Breast Cancer Immunohistochemistry Specimens Processed With VENTANA PD-L1 (SP142) Assay [0.03%]
VENTANA PD-L1（SP142）试验处理的复杂三阴性乳腺癌免疫组化标本的新型解读方法
Vicente Peg,Marta Abengozar-Muela,Jesús Acosta et al.
Vicente Peg et al.
Triple-negative breast cancer (TNBC) is challenging to treat because of its lack of specific molecular targets. The IMMUNOPEG study aimed to evaluate a novel structured method for interpreting TNBC immunohistochemistry specimens processed w...
Expression of MYD88 L265P Mutation in Subtypes of Diffuse Large B-Cell Lymphoma in the Pakistani Population [0.03%]
巴基斯坦人群弥漫性大B细胞淋巴瘤各亚型MYD88 L265P突变的表达
Muhammad Hamad Shabir,Hafeez Ud Din,Rafia Mahmood et al.
Muhammad Hamad Shabir et al.
MYD88 L265P mutation is a gain-of-function driver mutation. It is observed in a significant proportion of Waldenstrom macroglobulinemia and activated B-cell subtype of diffuse large B-cell lymphoma (DLBCL; non-germinal center subtype). The ...
IDO1 Expression and CD8+ T-Cell Levels Are Useful Prognostic Biomarkers in Preoperative Gastric Cancer Specimens Before Neoadjuvant Chemotherapy [0.03%]
新辅助化疗前胃癌标本中IDO1表达和CD8+T细胞水平是重要的预后生物标志物
Hu Chen,QiaoLin Zheng,Yiting Jiang et al.
Hu Chen et al.
The tumor immune microenvironment occupies an important position in gastric cancer. In this study, we investigated the relationship between indoleamine 2,3-dioxygenase 1 (IDO1), programmed cell death 1 ligand (PD-L1) expressioon, and CD8+ T...
Immunohistochemical Investigation of the Proliferative Activity of Odontogenic Cysts and Tumors [0.03%]
根尖周炎上皮的组织来源及生物学行为的研究进展与思考
Manal A Alsheddi
Manal A Alsheddi
Odontogenic cysts and tumors exhibit a broad spectrum of biological characteristics. Despite recent advances in understanding the complex nature of these lesions, relatively less is known about the molecular markers involved in key pathogen...
Chatchaphan Udompatanakorn,Worawan Sriphongphankul,Patrayu Taebunpakul
Chatchaphan Udompatanakorn
N6-methyladenosine (m6A) is the most abundant epigenetic RNA modification in eukaryotes and plays a role in various cancers in humans. This m6A modification is regulated by m6A writers, erasers, and readers. One of the m6A erasers is α-ket...
Automated Standardization of Melanin Bleaching Procedures of Heavily Pigmented Melanocytic Lesions With Low-Concentration Hydrogen Peroxide on an Automated Platform [0.03%]
基于自动化平台使用低浓度过氧化氢对色素型黑色素瘤病变进行黑素漂白的标准化研究
Chih-Ching Yeh,Yi-Jing Li,Jang-Shian Liang et al.
Chih-Ching Yeh et al.
Melanin is a natural pigment in the human body that is primarily found in the skin and hair. It protects the skin from damage by ultraviolet radiation. Although this pigment plays a crucial role in protecting the human body, it represents a...
Use of HSP105 in the Differential Diagnosis of Basaloid Skin Tumors: A Study of 73 Cases [0.03%]
热休克蛋白HSP105在基底细胞肿瘤鉴别诊断中的应用价值：73例回顾性分析
Li-Jia Deng,Kai-Yi Zhou,Qin-Xiao Wang et al.
Li-Jia Deng et al.
Background: Basaloid skin tumors include subtypes of basal cell carcinoma (BCC) and the basaloid variant of squamous cell carcinoma (SCC). Due to their similarity in pathology and clinical presentation, their diagnosis is...