The Role of Mutation Rates of GNAQ or GNA11 in Cases of Uveal Melanoma in Japan [0.03%]
日本眼脉络膜黑色素瘤GNAQ或GNA11突变率的作用
Jun Ominato,Takeo Fukuchi,Ayako Sato et al.
Jun Ominato et al.
GNAQ and GNA11 mutations are thought to be important for the tumorigenesis of uveal melanoma. Although previous studies have reported on mutation rates in cases of uveal melanoma, presently, no such report for the Japanese population exists...
Aberrant Cytokeratin 20 Reactivity in Epithelioid Malignant Mesothelioma: A Case Report [0.03%]
上皮样恶性间皮瘤中角蛋白20异常表达的病例报道
Rashmi Manur,Ihab Lamzabi
Rashmi Manur
Malignant mesothelioma is an uncommon neoplasm that should be distinguished from the more common pulmonary adenocarcinomas and other metastatic lesions. Although diagnosis is based on morphologic features, immunohistochemical stains such as...
Distribution of RANK and RANK Ligand in Normal Human Tissues as Determined by an Optimized Immunohistochemical Method [0.03%]
优化的免疫组化方法确定的人正常组织中RANK和RANKL的分布情况
Clive R Taylor,Daniel Branstetter,Edward Manna et al.
Clive R Taylor et al.
The expression and tissue distribution of RANK (Receptor Activator of Nuclear Factor κ B) and RANK Ligand (RANKL) are of critical interest in relation to efficacy and safety of antibodies against RANK or RANKL that are approved or under co...
Virtual Double Staining: A Digital Approach to Immunohistochemical Quantification of Estrogen Receptor Protein in Breast Carcinoma Specimens [0.03%]
虚拟双重染色：乳腺癌标本中雌激素受体蛋白免疫组化定量的数字方法
Nina Lykkegaard Andersen,Anja Brügmann,Giedrius Lelkaitis et al.
Nina Lykkegaard Andersen et al.
Visual assessment of immunohistochemically detected estrogen receptor protein is prone to interobserver and intraobserver variation due to its subjective evaluation. The aim of this study was to validate a new image analysis system based on...
Clinicopathologic Features of the Non-CNS Primary Ewing Sarcoma Family of Tumors in the Head and Neck Region [0.03%]
头颈部非中枢神经系统 ewing 梭形细胞肿瘤的临床病理特征分析
Chang Gok Woo,Bora Lee,Joon Seon Song et al.
Chang Gok Woo et al.
Ewing sarcoma family of tumor (ESFT) is a group of malignant neoplasms that affect children and young adults. Primary ESFT does not commonly arise from the head and neck region. This study aimed to elucidate the clinicopathologic characteri...
Interleukin (IL)-1, 4, 6, 7, 8, 10 Appearance in Congenital Intra-Abdominal Adhesions in Children Under 1 Year of Age [0.03%]
新生儿先天性腹腔内粘连的白细胞介素(IL)-1、4、6、7、8、10的表达
Anna Junga,Māra Pilmane,Zane Ābola et al.
Anna Junga et al.
Several cytokines have been studied for their potential role in adhesion formation. Regulatory role between the cytokine pathways has not yet to be defined. This study was designed to investigate the relation between proinflammatory and ant...
Leonardo Lordello,Martin E Bur,Esther Oliva et al.
Leonardo Lordello et al.
PAX8, estrogen receptor-α (ERα) and progesterone receptor (PR) are markers usually expressed in neoplasms of müllerian origin. We report a subdiaphragmal mass in a 41-year-old woman corresponding to a malignant biphasic tumor with nests ...
Charles W Myers,Sonal Bhimji-Patel,Mark Rees et al.
Charles W Myers et al.
The use of controls is a hallmark for quality control in anatomic pathology. However, standardization of controls between laboratories has been a significant issue. Differential processing techniques between institutions and a multitude of ...
TLE-1-Positive Angiomatoid Fibrous Histiocytoma Mimicking Synovial Sarcoma [0.03%]
TLE-1阳性血管型纤维组织细胞瘤误诊为滑膜肉瘤
Daniel J Zaccarini,Rana Naous,Yesha Sheth et al.
Daniel J Zaccarini et al.
Angiomatoid fibrous histiocytoma (AFH) is a rare soft tissue tumor most commonly seen in young adults and children. We report a case with morphology and immunohistochemistry supporting the diagnosis of synovial sarcoma. On core biopsy, the ...
Performance Assessment of Epidermal Growth Factor Receptor Gene Sequencing According to Sample Size in Daily Practice Conditions [0.03%]
每日实践条件下根据样本量评估表皮生长因子受体基因测序性能
Alejandro García,Constanza Lorente,María T Cuello et al.
Alejandro García et al.
Lung carcinoma is the main cause of cancer death worldwide. Adenocarcinoma molecular biomarkers have been discovered, and targeted therapies have been developed with encouraging results. The epidermal growth factor receptor gene is one of t...