Clinicopathological Features of Non-HPV-associated Common Differentiated Penile Squamous Cell Carcinoma: A Study of 55 Patients [0.03%]
55例非HPV相关阴茎分化型鳞癌的临床病理特征分析
Yanan Zou,Li Zhang,Ping Yang et al.
Yanan Zou et al.
To investigate the clinicopathological characteristics of non-HPV-related common differentiated penile squamous cell carcinoma, and to observe and analyze the changes of TP53 gene and the expression and significance of TP53, P16, programmed...
Interobserver and Interassay Concordance in HER2 Immunohistochemistry: Implications on HER2-Low Breast Cancer [0.03%]
HER2免疫组化检测的观察者间和试验间一致性：对低水平HER2乳腺癌的影响
Ozgur Can Eren,Orhun Cig Taskin,Murat Oktay et al.
Ozgur Can Eren et al.
Adopting a HER2-specific treatment approach for HER2-low breast cancer has been suggested after DESTINY-Breast04 (phase 3) trials. Hence, accurate pathologic evaluation gained higher importance, making interobserver agreement and interassay...
Comparison of Gastric Signet Ring Cell Carcinoma and Adenocarcinoma From Clinicopathologic Characteristics and Protein Expressions [0.03%]
基于临床病理特征和蛋白表达的胃 signet ring cell carcinoma 与腺癌比较研究
Jingwei Ma,Meng Zhu,Ning Zhang et al.
Jingwei Ma et al.
Signet ring cell carcinoma (SRCC) and adenocarcinoma (ADC) exhibit distinct characteristics, yet a comprehensive comparison is lacking. In this retrospective study from 2020 to 2024, we analyzed 568 gastric cancer cases, including 216 SRCC ...
Investigating Biomarkers in Primary Tumors and Lymph Node Metastases in Tongue Squamous Cell Carcinoma: An Immunohistochemical Perspective [0.03%]
舌鳞癌原发灶及淋巴结转移灶中生物标志物的免疫组化研究
Shahroo Etemad-Moghadam,Mojgan Alaeddini
Shahroo Etemad-Moghadam
This study aimed to gain insight into cancer progression and the metastatic process by analyzing protein expression patterns in primary, metastatic, and nonmetastatic tongue squamous cell carcinoma (TSCC), with a focus on understanding biom...
Distinct levels of DDIT3 Amplification in Dedifferentiated Liposarcoma Developing After DDIT3 Rearrangement in Myxoid Liposarcoma [0.03%]
发生DDIT3重排的黏液样脂肪肉瘤后发展成去分化的脂肪肉瘤时不同的DDIT3扩增水平
Uiree Jo,Min Jeong Song,Ji-Seon Jeong et al.
Uiree Jo et al.
Dedifferentiated liposarcoma (DDLPS) is a high-grade tumor characterized by its diverse histomorphology and development from atypical lipomatous tumor/well-differentiated liposarcoma (ALT/WDLPS). The variable morphology of DDLPS, particular...
Immunohistochemical Study on Programmed Death Ligand 1 (PD-L1) in Breast Carcinoma and Its Correlation With the Clinicopathological Parameters [0.03%]
乳腺癌组织中程序性死亡配体1(PD-L1)的免疫组化研究及其与临床病理参数的关系
Nada N Tamem,Shadia H Mabrouk,Zeinab A Shehabeldin et al.
Nada N Tamem et al.
Breast cancer (BC) is considered to be the second highest cause of cancer-related death in women. Antibodies targeting programmed death ligand 1 (PD-L1) have been approved for treating breast cancer. However, PD-L1 expression and its progno...
STAT6 Can Be Used in the Diagnosis of Hodgkin Lymphoma; There Are Differences in Expression Among Subtypes [0.03%]
STAT6可用于霍奇金淋巴瘤的诊断；不同亚型表达有差异
Deniz Bayçelebi,Şemsi Yildiz,Levent Yildiz et al.
Deniz Bayçelebi et al.
New markers are needed to aid in the diagnosis, typing, and determination of targeted treatment options in Hodgkin lymphoma. STAT6 is one of the most frequently reported mutations in classic Hodgkin tumors and can also be detected immunohis...
EWSR1::NFATC2 Rearranged Sarcoma: Distinct Clinicopathological Features From a Series of 5 Rare Cases [0.03%]
EWSR1::NFATC2重排肉瘤：5例罕见病例的临床病理特征分析
Balamurugan Thirunavukkarasu,Pragya Shukla,Deepam Pushpam et al.
Balamurugan Thirunavukkarasu et al.
Ewing sarcoma (ES) is an undifferentiated round cell sarcoma affecting children and young adults. It is characterized by gene fusions involving one of the gene members of FET family (EWSR1) and ETS transcription family members. Recent studi...
Immune Checkpoint Molecule Expression, 9p24.1 Gene Alterations, and Tumor Microenvironment of Primary Central Nervous System Lymphomas and Their Clinical Relevance [0.03%]
原发中枢神经系统淋巴瘤的免疫检查点分子表达、9p24.1基因改变及其临床意义及肿瘤微环境
Dilara Akbulut,Seher Yuksel,Ekin Kircali et al.
Dilara Akbulut et al.
Primary central nervous system large B-cell lymphoma (PCNS-LBCL) is a rare, aggressive lymphoma that affects immune-privileged sites. Immune checkpoint molecules have been implicated in its aggressive biology, and promising results have eme...
Tissue Factor Pathway Inhibitor-2 Expression in Uterine Cervical Clear Cell Carcinoma: A Potential Biomarker for Clinical Diagnosis [0.03%]
子宫颈透明细胞癌中组织因子途径抑制物-2的表达：一种潜在的临床诊断生物标志物
Ryuji Kawaguchi,Tomoko Uchiyama,Sumire Sugimoto et al.
Ryuji Kawaguchi et al.
Cervical clear cell carcinoma (CCCC) is an extremely rare histologic type of uterine cancer. Tissue factor pathway inhibitor-2 (TFPI2) is a serine protease inhibitor that was recently shown to be expressed in ovarian clear cell carcinoma an...