Hepatocyte-like Versus Mesenchymal Stem Cells in CCl4-induced Liver Fibrosis [0.03%]
CCl4诱导的肝纤维化中小 hepatocyte样细胞与间充质干细胞的区别
Suzy Fayez Ewida,Asmaa Gaber Abdou,Amal Abd El-Rasol Elhosary et al.
Suzy Fayez Ewida et al.
It is still a matter of debate as to whether in vitro mesenchymal stem cell (MSC)-derived hepatocytes may efficiently repopulate a host liver to provide adequate functional substitution. The aim of this study is to assess the efficacy and c...
Paraffin-embedded Tissue Fragment Suspension (PETFS): A Novel Method for Quality Control Preparation in Immunohistochemistry [0.03%]
石蜡包埋组织碎片悬液(PETFS)在免疫组化质量控制中的新型制备方法研究
Wei Ding,Ke Huang,Bingjian Lü et al.
Wei Ding et al.
Immunohistochemistry (IHC) is one of the most important adjunctive techniques in surgical pathology. Quality controls are essential for staining interpretation. The most common controls are cut from the formalin-fixed, paraffin-embedded tis...
Invasive Duct Carcinoma of the Breast With Dominant Signet-Ring Cell Differentiation: A Microsatellite Stable Tumor With Aggressive Behavior [0.03%]
主导型管内导管癌伴签状环细胞分化：一种具有侵袭性的微卫星稳定肿瘤
Debajyoti Chatterjee,Amanjit Bal,Ashim Das et al.
Debajyoti Chatterjee et al.
Aims: Invasive duct carcinoma, no special type (IDC, NST), of the breast with signet-ring cell differentiation is uncommon. This study was undertaken to describe the clinicopathologic characteristics of IDC, NST, with dom...
Angel Fernandez-Flores,David S Cassarino
Angel Fernandez-Flores
Some poroid neoplasias are known to show apocrine differentiation (ie, differentiation toward the folliculosebaceous and the apocrine units). In this sense, it is somewhat surprising that the immunoexpression of androgen receptors (ARs) has...
A Case of Sinonasal Melanoma With Unusual Primary Exon 17 KIT D820G Mutation [0.03%]
特殊原发性第17号外显子KIT(D820G)突变型鼻腔黑色素瘤病例报告
Emanuela Pilozzi,Armando Bartolazzi,Flavio Fochetti et al.
Emanuela Pilozzi et al.
Sinonasal melanomas are rare neoplasms with poor prognosis that may harbor KIT and NRAS genes mutations. Molecular alterations represent possible targets of tailored therapeutic approaches. We describe the case of a 74-year-old patient with...
Comparative Assessment of 4 Methods to Analyze MGMT Status in a Series of 121 Glioblastoma Patients [0.03%]
评估MGMT状态的四种方法在121例胶质母细胞瘤患者中的比较分析
Chih-Yi Hsu,Hsiang-Ling Ho,Shih-Chieh Lin et al.
Chih-Yi Hsu et al.
The O-methylguanine-DNA-methyltranferase (MGMT) status is a powerful predictor of response to temozolomide for newly diagnosed glioblastoma (GBM) patients, and it is commonly assessed by immunohistochemistry (IHC), methylation-specific poly...
A Selected Immunohistochemical Panel Aids in Differential Diagnosis and Prognostic Stratification of Subtypes of High-grade Endometrial Carcinoma: A Clinicopathologic and Immunohistochemical Study at a Single Institution [0.03%]
选择性免疫组化谱在高级别子宫内膜癌分型及预后分层中的应用价值：单中心临床病理和免疫组化研究
Orhun Çiğ Taskin,Semen Onder,Samet Topuz et al.
Orhun Çiğ Taskin et al.
This study aimed to investigate whether a selected immunohistochemical panel (estrogen receptor, p53, ARID1A, PPP2R1A, HNF-1β) could contribute to the diagnostic process of high-grade endometrial carcinomas (HG-ECs). We also aimed to analy...
New Robust and Reproducible Stereological IHC Ki67 Breast Cancer Proliferative Assessment to Replace Traditional Biased Labeling Index [0.03%]
新的稳健且可重复的立体定向IHC Ki67乳腺癌增殖评估方法以替代传统的有偏标记指数
Gilbert Bigras,Wei-Feng Dong,Sarah Canil et al.
Gilbert Bigras et al.
There is a pressing need for an objective decision tool to guide therapy for breast cancer patients that are estrogen receptor positive and HER2/neu negative. This subset of patients contains a mixture of luminal A and B tumors with good an...
IHC Optical Density Score: A New Practical Method for Quantitative Immunohistochemistry Image Analysis [0.03%]
一种新的免疫组化图像定量分析方法:IHC光学密度评分法
Seyed Morteza Seyed Jafari,Robert E Hunger
Seyed Morteza Seyed Jafari
Cancer Antigen 125 (CA125, MUC16) Protein Expression in the Diagnosis and Progression of Pancreatic Ductal Adenocarcinoma [0.03%]
癌抗原125(CA125，MUC16)在胰腺导管腺癌诊断和进展中的蛋白表达研究
Kun Jiang,Elaine Tan,Zena Sayegh et al.
Kun Jiang et al.
Pancreatic ductal adenocarcinoma (PDAC) is an aggressive carcinoma, with most patients diagnosed at an advanced stage, with a 5-year survival rate of around 5%. An urgent need exists for identifying better diagnostic, prognostic, and therap...