Loss of Cytokeratin 7 (CK7) Expression Can be Seen in Significant Proportion of Solid Papillary Carcinoma of Breast and Associated Invasive Component [0.03%]
乳腺实性乳头状癌及其浸润性成分中细胞角蛋白7(CK7)表达的丢失占有相当大的比例
Fahad Sheikh,Susan Fineberg,Javier Laurini et al.
Fahad Sheikh et al.
Abstract: Cytokeratin 7 (CK7) is a marker of epithelial differentiation and is positive in >90% of breast carcinomas. In the right clinical setting, coexpression of CK7 and GATA3 is considered as strong evidence of breast...
The Impact of Type, Dose, and Duration of Prebiopsy Corticosteroids Use on Histomorphology and Immunohistochemical Stains in B-Cell Lymphoma: A Case-Control Study to Highlight the "Atypical" Cytoplasmic and Extra-Cellular Granular Staining Pattern of CD20 [0.03%]
抗生素使用对B细胞淋巴瘤组织形态和免疫组化染色的影响：一项病例对照研究强调CD20的“非典型”胞浆和细胞外颗粒状染色模式
Kritika Krishnamurthy,Xing Li,Jui Choudhuri et al.
Kritika Krishnamurthy et al.
Large/aggressive B-cell lymphomas are diverse both in terms of clinical presentations and treatment response. Diagnostic pathologic evaluation typically begins with a CD20/CD3 immunohistochemical panel. Prebiopsy steroid treatment has been ...
Membranous Staining of CD10 Is Related to Steatosis Changes in Hepatocellular Carcinoma: An Investigation of CD10 Stainning in Hepatocellular Carcinoma, Focal Nodular Hyperplasia, and Intrahepatic Cholangiocarcinoma [0.03%]
肝细胞癌中CD10的膜染色与脂肪变性改变有关：对肝细胞癌，局灶结节增生和胆管细胞癌中CD10 染色的研究
Caiyan Wen,Chuqiang Huang,Shouguo Chen et al.
Caiyan Wen et al.
Aims: To investigate the staining patterns of CD10 in hepatocellular carcinoma (HCC), focal nodular hyperplasia (FNH), and intrahepatic cholangiocarcinoma (ICC). ...
The Prevention of Fatal Tauopathy in a Mouse Model of Alzheimer Disease by Blocking BCL2 [0.03%]
通过抑制BCL2来阻止阿尔茨海默病小鼠模型中的致死tauopathy
Gerard J Nuovo,Madison Rice,Nicola Zanesi et al.
Gerard J Nuovo et al.
A major goal in Alzheimer disease (AD) research is the reduction of the abnormal tau burden. Using multispectral analyses on brain tissues from humans who died of AD it was documented that neurons with hyperphosphorylated tau protein accumu...
Claudin 18.2 Immunohistochemistry Expression in Gastric Cancer: A Systematic Review [0.03%]
Claudin 18.2在胃癌中的免疫组化表达：系统性回顾
Joan Lop Gros,Pablo Santiago Díaz,Mónica Larrubia Loring et al.
Joan Lop Gros et al.
Claudin 18.2 is a transmembrane protein, part of the tight-junction complex, selectively expressed in gastric epithelium. It is showing promising results as a target in advanced gastric cancer in phase 3 clinical trials using a monoclonal a...
Changes in HER2 Amplification Status for Breast Cancer Patients After Immunohistochemistry Directed In Situ Hybridization [0.03%]
免疫组化指导的原位杂交后的乳腺癌患者HER2基因扩增状态的变化
Cameron Beech,Diane M Wilcock,Kristina H Moore et al.
Cameron Beech et al.
The 2018 ASCO/CAP guidelines for HER2 testing for breast cancer implemented the addition of immunohistochemistry (IHC) directed in situ hybridization (ISH) recount to resolve equivocal results. The implementation of an additional 2+ IHC-dir...
TP53 Alterations Are an Independent Adverse Prognostic Indicator in Pseudomyxoma Peritonei of Appendiceal Origin Following Cytoreductive Surgery and Intraperitoneal Chemotherapy [0.03%]
肿瘤板状型腹膜假黏液瘤经充分减瘤术后行腹腔热灌注化疗预后不良的独立预测因素是TP53基因变异
Nuha Shaker,Jon Davison,Joshua Derby et al.
Nuha Shaker et al.
Histologic grade is a key predictor for pseudomyxoma peritonei (PMP) of appendiceal origin that is used to guide clinical management. However, some tumors demonstrate disease behavior that deviates from their histologic grade. A recent stud...
Immunohistochemical Expression of PAX8 in Central Nervous System Hemangioblastomas: A Potential Diagnostic Pitfall for Neuropathologists [0.03%]
PAX8在中枢神经系统血管母细胞瘤中的免疫组化表达——神经病理学诊断中的潜在陷阱
Giuseppe Broggi,Jessica Farina,Valeria Barresi et al.
Giuseppe Broggi et al.
The histologic differential diagnosis between intracranial hemangioblastoma (HB) and metastatic clear cell renal cell carcinoma may be challenging, especially considering that both tumors exhibit clear cell morphology and can be associated ...
Overexpression of MAGE-A2 is Related to the Malignant Degree and Progression of Disease in Patients With Clear Cell Renal Cell Carcinoma [0.03%]
MAGE-A2过表达与透明细胞肾细胞癌患者的恶性程度及疾病进展有关
Monireh Mohsenzadegan,Fahimeh Fattahi,Elham Kalantari et al.
Monireh Mohsenzadegan et al.
Melanoma antigen gene-A2 (MAGE-A2) is one of the most cancer-testis antigens overexpressed in a variety of malignancies. However, the expression of MAGE-A2 for clinical values in the pathophysiology of renal cell carcinoma (RCC) is unknown....