Marissa J White,Ashley Cimino-Mathews
Marissa J White
Mesenchymal and spindle cell tumors of the breast represent a broad and heterogeneous group of lesions that may be sampled on core needle biopsy or surgical excision. Mesenchymal lesions unique to the breast are those that derive from the s...
Gastrointestinal Stromal Tumors: Variants and Some Pitfalls That They Create [0.03%]
胃肠间质瘤：变异及其带来的某些陷阱
Ammoura Ibrahim,Elizabeth A Montgomery
Ammoura Ibrahim
The diagnosis of gastrointestinal stromal tumors (GISTs) is generally straightforward using a combination of histologic evaluation and pertinent immunohistochemical staining with CD117/kit and DOG-1 (discovered on GIST) antibodies. However,...
Kshitij Arora,Andrew E Rosenberg
Kshitij Arora
This review summarizes the clinicopathologic features of various lipomatous tumors of soft tissue and addresses some recent conceptual issues relating to adipocytic neoplasms, such as atypical spindle cell/pleomorphic lipomatous tumor and m...
W Glenn McCluggage,Carlos Parra-Herran
W Glenn McCluggage
Mona Alfaraidi,C Blake Gilks,Lynn Hoang
Mona Alfaraidi
The classification of vulvar squamous cell carcinoma (VSCC), as in endometrial cancer, has shifted from the histology-based descriptors toward molecular-based identifiers. Recently, it has been reported that there are 3 genetically distinct...
Common Diagnostic Challenges in Genitourinary Mesenchymal Tumors: A Practical Approach [0.03%]
泌尿生殖道间叶源性肿瘤的常见诊断挑战：实用方法
Jaylou M Velez Torres,Oleksandr N Kryvenko
Jaylou M Velez Torres
Mesenchymal neoplasms within the genitourinary tract include a wide spectrum of tumors, ranging from benign to malignant, and tumors of uncertain malignant potential. Except for stromal tumors of the prostate, which originate from the speci...
The Role of Predictive and Prognostic Biomarkers in Lower Female Genital Tract Pathology: PD-L1, MMR, HER2, p16, p53, and Beyond [0.03%]
低女性生殖道病理中预测性和预后性生物标志物的作用：PD-L1、MMR、HER2、p16、p53等标志物的重要性
Anne M Mills,Andre Pinto
Anne M Mills
Biomarkers play a crucial role in the diagnosis, treatment planning, and prognosis of premalignant and malignant lesions and are increasingly used in neoplasia of the lower female genital tract (LFGT) including the cervix, vagina, and vulva...
Karina Colossi Furlan,Bruce M Wenig
Karina Colossi Furlan
The majority of neoplasms of the head and neck are of epithelial origin primarily including mucosal squamous cell neoplasms (papillomas; squamous cell carcinoma) as well as salivary gland neoplasms. However, the full spectrum of mesenchymal...
Andre Pinto,Andrew E Rosenberg
Andre Pinto
STK11 Adnexal Tumor: Exploring the Association With Peutz-Jeghers Syndrome and its Distinction From Morphologic Mimickers [0.03%]
STK11卵巢肿瘤：与佩吉特-约赫尔斯综合征的关联及其与形态类似病变的区别
Jennifer A Bennett,Esther Oliva
Jennifer A Bennett
STK11 adnexal tumor is a novel malignant neoplasm of uncertain histogenesis frequently arising in a para-adnexal location and associated with Peutz-Jeghers syndrome in ∼50% of patients. Its broad morphologic spectrum and nonspecific immuno...