Nicole B Johnson,Laura C Collins
Nicole B Johnson
Certain nonmalignant lesions encountered on percutaneous breast biopsies pose dilemmas with regard to the most appropriate clinical management subsequent to needle biopsy (ie, surgical excision vs. follow-up). These lesions include columnar...
Multiple spontaneous liver cell adenomas of different types (liver adenomatosis) [0.03%]
多种类型的自发性肝细胞腺瘤(肝腺瘤病)
Michele Bisceglia,Alberto Gatta,Anna Tomezzoli et al.
Michele Bisceglia et al.
In 1999, Nguyen et al divided focal nodular hyperplasia (FNH) in 2 groups, the classical and nonclassical. The former also included those cases of FNH with classical characteristics exhibited "on a subtle scale," whereas the latter included...
Sanja Dacic
Sanja Dacic
Current World Health Organization (WHO) classification of lung adenocarcinomas includes noninvasive bronchioloalveolar carcinoma (BAC) and several patterns of invasive adenocarcinoma. The most common is a mixed subtype of adenocarcinoma. Th...
Daniela S Allende,Lisa M Yerian
Daniela S Allende
Gastroesophageal reflux disease (GERD) is a common disease frequently encountered by surgical pathologists. Although the pathogenesis and clinical features of the disease have been studied for years, many unanswered questions remain. Typica...
Selected topics in the evaluation of pediatric gastrointestinal mucosal biopsies [0.03%]
儿童胃肠粘膜活检的评价要点精选
Jennifer R Scudiere,Anirban Maitra,Elizabeth A Montgomery
Jennifer R Scudiere
The practice of pediatric gastrointestinal pathology provides specific challenges to the pathologist. Often the clinical information accompanying a biopsy specimen will read simply, "failure to thrive." Other situations, such as the evaluat...
The discovery of common recurrent transmembrane protease serine 2 (TMPRSS2)-erythroblastosis virus E26 transforming sequence (ETS) gene fusions in prostate cancer: significance and clinical implications [0.03%]
前列腺癌中常见转膜丝氨酸蛋白酶2(E26转化系列)基因融合的发现及其意义和临床影响
Rajal B Shah,Arul M Chinnaiyan
Rajal B Shah
Recurrent gene fusions and chromosomal rearrangements were previously thought to be the primary oncogenic mechanism of hematological malignancies and sarcomas. The recent discovery of recurrent gene fusions in a majority of prostate cancers...
Melissa P Pulitzer,Bijal D Amin,Klaus J Busam
Melissa P Pulitzer
Merkel cell carcinoma (MCC) is synonymous with primary cutaneous neuroendocrine carcinoma. It tends to affects elderly whites, but there is also an increased incidence among immunosuppressed patients. The recent identification of a novel po...
Alexandra N Kalof,Kumarasen Cooper
Alexandra N Kalof
D2-40 is a commercially available monoclonal antibody directed against human podoplanin, a transmembrane mucoprotein that is expressed in lymphatic endothelial cells. Since its introduction, D2-40 immunoexpression has been described in a va...
Lupus mastitis: a clinicopathologic review and addition of a case [0.03%]
lupusmastitis：临床病理回顾并新增一例患者报告
Thomas A Summers Jr,Michael B Lehman,Ross Barner et al.
Thomas A Summers Jr et al.
Lupus mastitis (LM) is a rare presentation of lupus erythematosus profundus or lupus panniculitis, an unusual and rare clinical variant of lupus erythematosus itself in which the inflammatory reaction occurs primarily in the deep subcutaneo...
Epstein-Barr virus in lymphoproliferative processes: an update for the diagnostic pathologist [0.03%]
淋巴增生性病变中的爱泼斯坦-巴尔病毒：诊断病理学家的最新研究进展
Siok-Bian Ng,Joseph D Khoury
Siok-Bian Ng
The Epstein-Barr virus is an orally transmitted herpesvirus that is widespread in human populations and exhibits marked B-cell tropism. It is associated with more human neoplasms than any other known virus, and its role in the pathogenesis ...