Selective pathologies of the head and neck in children: a developmental perspective [0.03%]
儿童头部和颈部疾病的特异性：发展性观点
John A Ozolek
John A Ozolek
The range of pathology seen in the head and neck region is truly amazing and to a large extent probably mirrors the complex signaling pathways and careful orchestration of events that occurs between the primordial germ layers during the dev...
Hala Faragalla,Ilan Weinreb
Hala Faragalla
Olfactory neuroblastoma (ONB) is a malignant neuroectodermal tumor that typically occurs in the superior nasal cavity. It is a distinct entity with features that include nesting, low-grade stippled nuclei, and neurofibrillary stroma with fo...
Oisin Houghton,W Glenn McCluggage
Oisin Houghton
p63 plays a key role in epithelial development in various organs, being expressed in myoepithelial cells and in basal cells of stratified epithelia. In the female genital tract, p63 is expressed in the basal and parabasal cells of mature ce...
Benign cartilaginous tumors of bone: from morphology to somatic and germ-line genetics [0.03%]
骨的良性软骨肿瘤：从形态学到体细胞性和种系遗传学
Salvatore Romeo,Pancras C W Hogendoorn,Angelo Paolo Dei Tos
Salvatore Romeo
Benign cartilaginous tumors of bones, intrinsic to their name, are tumors forming cartilaginous matrix with a clinically benign behavior. In this group, we recognize osteochondromas, (en)chondromas, chondroblastomas, and chondromyxoid fibro...
Lymphocytic disorders of the gastrointestinal tract: a review for the practicing pathologist [0.03%]
胃肠黏膜淋巴细胞浸润和疾病的病理学诊断及鉴别诊断——回顾性分析
Susanne W Carmack,Richard H Lash,James M Gulizia et al.
Susanne W Carmack et al.
Increased numbers of intraepithelial lymphocytes (lymphocytosis) can be found in the esophagus, stomach, small intestine, and colon in a variety of clinical circumstances. This review, directed at practicing pathologists, portrays the norma...
Poorly differentiated thyroid carcinoma: a cytologic-histologic review [0.03%]
未分化型甲状腺癌的细胞学和组织病理学特征回顾分析
Massimo Bongiovanni,Peter M Sadow,William C Faquin
Massimo Bongiovanni
The term poorly differentiated thyroid carcinoma (PDTC) was first proposed in the 1980s, but it was not definitively recognized as a distinct pathologic entity until the most recent classification of endocrine tumors by the World Health Org...
Ovarian low-grade and high-grade serous carcinoma: pathogenesis, clinicopathologic and molecular biologic features, and diagnostic problems [0.03%]
低级别和高级别浆液性卵巢癌：发病机制、临床病理及分子生物学特点和诊断问题
Russell Vang,Ie-Ming Shih,Robert J Kurman
Russell Vang
Ovarian serous carcinomas have been graded using various systems. Recently, a 2-tier system in which tumors are subdivided into low grade and high grade has been proposed. This approach is simplistic, reproducible, and based on biologic evi...
John G Batsakis,Alberto Ayala,Adel K El Naggar
John G Batsakis
Glypican-3: a novel diagnostic marker for hepatocellular carcinoma and more [0.03%]
Glypican-3：肝细胞癌的新型诊断标记物及其更多作用
Dina H Kandil,Kumarasen Cooper
Dina H Kandil
Glypican-3 (GPC3) is a heparan sulfate proteoglycan that plays an important role in cell growth and differentiation. GPC3 function is tissue dependent. In some tissues, GPC3 acts as a tumor suppressor gene, whereas in others, it acts as an ...
Raquel Portugal,Esther Oliva
Raquel Portugal
The utility of calretinin was first described in the diagnosis of mesothelioma. In the female genital tract, calretinin was initially reported in Wolffian remnants and related lesions and later used in the diagnosis of sex cord stromal tumo...