Follicular Neoplasm of Thyroid Revisited: Current Differential Diagnosis and the Impact of Molecular Testing [0.03%]
甲状腺滤泡性肿瘤的再评价:当前鉴别诊断及分子检测的影响
N Paul Ohori,Michiya Nishino
N Paul Ohori
The diagnosis of "follicular neoplasm" (FN) in thyroid cytopathology has a long history that originated not long after the practice of fine-needle aspiration (FNA) of thyroid nodules. From the outset, this interpretive category was intended...
Alessandro Gambella,Marco Volante,Mauro Papotti
Alessandro Gambella
Adrenal cortical carcinoma (ACC) is a rare and aggressive malignancy that poses challenging issues regarding the diagnostic workup. Indeed, no presurgical technique or clinical parameters can reliably distinguish between adrenal cortical ad...
SWI/SNF-deficient Malignancies: Optimal Candidates for Immune-oncological Therapy? [0.03%]
SWI/SNF缺陷型恶性肿瘤:免疫治疗的最优选择?
Abbas Agaimy
Abbas Agaimy
Inactivation of different subunits of the SWItch/sucrose nonfermentable (SWI/SNF) chromatin remodeling complex has emerged as one of the most frequent genetic pathways driving a variety of neoplasms of diverse histogenesis, originating in d...
From Malignant Thyroid Teratoma to Thyroblastoma: Evolution of a Newly-recognized DICER1 -associated Malignancy [0.03%]
从甲状腺恶性畸胎瘤到甲状腺原基细胞瘤:一种新认识的DICER1相关肿瘤的演变
Lisa M Rooper
Lisa M Rooper
Thyroblastoma is a novel thyroid malignancy included in the 5th Edition WHO Classification of Endocrine and Neuroendocrine Tumours. The majority of tumors now classified as thyroblastoma were originally regarded to be malignant thyroid tera...
An Overview of Pituitary Neuroendocrine Tumors (PitNET) and Algorithmic Approach to Diagnosis [0.03%]
垂体神经内分泌肿瘤(PitNETs)的诊疗概述和诊断算法
Maria A Gubbiotti,Zubair Baloch
Maria A Gubbiotti
The diagnostic algorithm and nomenclature of pituitary neuroendocrine tumors have evolved over the past decade, beginning with simpler categorical schemes focused on histomorphologic features and moving to a more sophisticated lineage-speci...
Small Biopsy and Cytology of Pulmonary Neuroendocrine Neoplasms: Brief Overview of Classification, Immunohistochemistry, Molecular Profiles, and World Health Organization Updates [0.03%]
肺神经内分泌肿瘤的小活检和细胞学:分类、免疫组化、分子特征及世界卫生组织更新的简要概述
Simon Sung,Jonas J Heymann,Michelle Garlin Politis et al.
Simon Sung et al.
Pulmonary neuroendocrine neoplasms comprise ~20% of all lung tumors. Typical carcinoid, atypical carcinoid, small cell carcinoma, and large cell neuroendocrine carcinoma represent the 4 major distinct subtypes recognized on resections. This...
Cystic Salivary Gland Neoplasms: Diagnostic Approach With a Focus on Ancillary Studies [0.03%]
囊性涎腺肿瘤的诊断方法及辅助检查重点
Efrain A Ribeiro,Zahra Maleki
Efrain A Ribeiro
Cystic salivary gland cytology can be challenging due to the fact that a cystic mass can be the clinical presentation of both non-neoplastic and neoplastic conditions. Neoplastic lesions consist of both benign and malignant neoplasms. The c...
Salivary Gland Intraductal Carcinoma: How Do 183 Reported Cases Fit Into a Developing Classification [0.03%]
唾液腺导管内癌:183例报告如何适应于一个发展中的分类体系?
Lester D R Thompson,Justin A Bishop
Lester D R Thompson
Salivary gland intraductal carcinoma (IDC) is a very uncommon group of neoplasms. Many names, variations in diagnostic criteria, and newly observed molecular findings (including NCOA4 :: RET , TRIM27 :: RET , HRAS point mutations, and PIK3C...
Epithelioid Vascular Lesions: The Differential Diagnosis and Approach in Cytology and Small Biopsies [0.03%]
上皮样血管病变的细胞学和小活检的鉴别诊断及处理策略
Nabil Tabish,Sara E Monaco
Nabil Tabish
Vascular neoplasms are rare tumors with a multitude of clinical presentations and behavior, which make accurate identification and subclassification challenging on limited small biopsies. Within the spectrum of these lesions, the ones with ...
Esther Diana Rossi,Pietro Tralongo,Vincenzo Fiorentino et al.
Esther Diana Rossi et al.
Fine needle aspiration is a well-known procedure for the diagnosis and management of thyroid lesions, representing the first diagnostic tool for the definition of their nature. In clinical practice, a thyroid nodule can be classified as sol...