Nipple Lesions of the Breast: An Update on Morphologic Features, Immunohistochemical Findings and Differential Diagnosis [0.03%]
乳腺乳头病变:形态学特征、免疫组化表现及鉴别诊断的新认识更新
Edi Brogi,Cristian Scatena
Edi Brogi
Because of the unique anatomic structure of the nipple, a few specific breast lesions occur only at this site. Large lactiferous sinuses may be involved by inflammatory conditions such as squamous metaplasia of lactiferous ducts and ductal ...
Thomas J Lawton
Thomas J Lawton
The standard of care for invasive cancers of the breast has been and continues to be to evaluate them for breast prognostic markers: estrogen receptor, progesterone receptor, and human epidermal growth factor receptor 2 by immunohistochemis...
Is it Time to Retire the Term of Low-Grade Ductal Carcinoma in Situ and Replace it With Ductal Neoplasia? [0.03%]
是时候让导管原位癌这个术语退役,并用导管上皮不典型增生取代它了吗?
Shahla Masood,Melvin J Silverstein
Shahla Masood
As the leading cause of cancer morbidity and the second leading cause of cancer mortality among women, breast cancer continues to remain a major global public health problem. Consequently, significant attention has been directed toward earl...
The Role of Novel Immunohistochemical Markers for Special Types of Breast Carcinoma [0.03%]
新型免疫组化标记物在特殊类型乳腺癌中的作用
Anne Grabenstetter,Timothy M DAlfonso
Anne Grabenstetter
Some histologic special types of breast carcinoma harbor specific recurrent genetic alterations that are not seen in other types of breast carcinoma (no special type), namely adenoid cystic carcinoma, secretory carcinoma, and tall cell carc...
Future Practices of Breast Pathology Using Digital and Computational Pathology [0.03%]
数字和计算病理学在乳腺病理中的未来应用与发展
Matthew G Hanna,Edi Brogi
Matthew G Hanna
Pathology clinical practice has evolved by adopting technological advancements initially regarded as potentially disruptive, such as electron microscopy, immunohistochemistry, and genomic sequencing. Breast pathology has a critical role as ...
David Suster,Saul Suster
David Suster
The classification of thymoma continues to be a source of controversy in pathology. The difficulties in histologic classification are evident from the number of proposals that have been offered over the years, as well as for the continuous ...
Invasive Squamous Cell Carcinoma of the Cervix: A Review of Morphological Appearances Encountered in Human Papillomavirus-associated and Papillomavirus-independent Tumors and Precursor Lesions [0.03%]
与人乳头瘤病毒相关和非依赖乳头瘤病毒的宫颈鳞状细胞癌:形态表现回顾及前驱病变
Simona Stolnicu,Douglas Allison,Andrei Patrichi et al.
Simona Stolnicu et al.
Cervical cancer is the fourth most common cancer among women globally. Historically, human papillomavirus (HPV) infection was considered necessary for the development of both precursor and invasive epithelial tumors of the cervix; however, ...
TRPS1, a New Promising Marker for Assessment of Distant Metastatic Breast Cancer [0.03%]
TRPS1:评估乳腺癌远处转移的新标志物
Patrick J McIntire,Lauren A Duckworth,John Van Arnam et al.
Patrick J McIntire et al.
This article reviewed the identification of breast cancer in the distant metastatic setting through traditional immunohistochemical markers, such as mammaglobin and GATA3, compared with the novel immunohistochemical stain, Trichorhinophalan...
The Significance of Recognition of Human Epidermal Growth Factor 2 Low in Breast Cancer Therapy [0.03%]
乳腺癌治疗中低表达人表皮生长因子受体2的意义分析
Gary Tozbikian
Gary Tozbikian
In response to recent clinical trials that demonstrate the clinical benefit of antibody-drug conjugate drug therapy in breast cancer (BC) with human epidermal growth factor 2 (HER2) immunohistochemical scores of 1+ or 2+ and negative in sit...