Artificial Intelligence-Enabled Prostate Cancer Diagnosis and Prognosis: Current State and Future Implications [0.03%]
人工智能赋能的前列腺癌诊断和预后：现状与未来意义
Swati Satturwar,Anil V Parwani
Swati Satturwar
In this modern era of digital pathology, artificial intelligence (AI)-based diagnostics for prostate cancer has become a hot topic. Multiple retrospective studies have demonstrated the benefits of AI-based diagnostic solutions for prostate ...
Rajal B Shah,Cristina Magi-Galluzzi
Rajal B Shah
Update on Selected High-grade Renal Cell Carcinomas of the Kidney: FH-deficient, ALK-rearranged, and Medullary Carcinomas [0.03%]
选定的高级肾细胞癌的最新信息：FH缺乏型、ALK重排型和髓质型癌症
Ying-Bei Chen
Ying-Bei Chen
High-grade renal cell carcinoma (RCC), often diagnosed at advanced stages, significantly contributes to renal cancer-related mortality. This review explores the progress in understanding specific subtypes of high-grade RCC, namely fumarate ...
Current Challenges and Controversies in Colorectal Carcinoma Pathologic Staging-A Practical Guide [0.03%]
当前结直肠癌病理分期的挑战和争议——实用指南
Ian Clark,Ansa Mehreen,Paxton V Dickson et al.
Ian Clark et al.
The pathologic assessment of colorectal carcinoma specimens plays a crucial role in the therapeutic management of patients and disease prognostication. The TNM staging system is used globally and is a critical component of colorectal carcin...
Andrés M Acosta,Muhammad T Idrees,Daniel M Berney et al.
Andrés M Acosta et al.
Testicular sex cord-stromal tumors (TSCSTs) are relatively rare, representing ~5% of testicular neoplasms overall. Historically, TSCSTs have been classified into 3 major entities: Leydig cell tumor, Sertoli cell tumor, and granulosa cell tu...
#PathX: #PathTwitter's Transformation and a Discussion on Different Social Media Platforms Used by Pathologists in 2024 [0.03%]
#PathX：2024年PathTwitter的转型及其他病理学家使用的社交媒体平台讨论
Casey P Schukow,Lavisha S Punjabi,Fadi W Abdul-Karim
Casey P Schukow
#PathTwitter is a well-known virtual community that has historically been positive for pathologists, trainees, and medical students worldwide to communicate, collaborate, and connect for free. However, in 2023, the popular social media plat...
Jianping Zhao,Charles C Guo,Priya Rao
Jianping Zhao
Upper urinary tract urothelial carcinoma (UTUC) is an uncommon malignancy involving the renal pelvis and ureter. Careful pathologic analysis plays a critical role in the diagnosis and clinical management of UTUC. In combination with clinica...
DNA Damage Response and Mismatch Repair Gene Defects in Advanced and Metastatic Prostate Cancer [0.03%]
转移性前列腺癌的DNA损伤反应和错配修复基因缺陷
Dilara Akhoundova,Paola Francica,Sven Rottenberg et al.
Dilara Akhoundova et al.
Alterations in DNA damage response (DDR) and related genes are present in up to 25% of advanced prostate cancers (PCa). Most frequently altered genes are involved in the homologous recombination repair, the Fanconi anemia, and the mismatch ...
Multicystic Clear Cell Renal Tumors With Low-grade Nuclear Features: Time to Include TFE3 Translocation-associated Carcinomas [0.03%]
低级别核特征的多囊透明细胞肾肿瘤：是时候纳入TFE3基因易位相关癌了
Qi Cai,Jeffrey Gagan,Prasad Koduru et al.
Qi Cai et al.
TFE3 -rearranged renal cell carcinoma (RCC) is a distinct, uncommon entity with more than 20 different fusion partners identified; however, histomorphology may be suggestive of specific fusion partners in select TFE3 -rearranged RCCs. For e...
Renal Cell Carcinoma Associated With TSC/MTOR Genomic Alterations: An Update on its Expanding Spectrum and an Approach to Clinicopathologic Work-up [0.03%]
与TSC/MTOR基因组改变相关的肾细胞癌：不断扩大的谱系及其临床病理学检查方法的更新
Rajal B Shah,Rohit Mehra
Rajal B Shah
Renal cell carcinoma (RCC) with tuberous sclerosis complex (TSC)/mammalian target of rapamycin (MTOR) pathway-related genomic alterations have been classically described in hereditary TSC syndrome setting involving germline mutations, where...