Anakinra in Recurrent Pericarditis: Current Evidence on Clinical Use, Effectiveness, and Safety [0.03%]
阿那白滞素治疗复发性心包炎：目前临床应用、疗效和安全性的证据评估
Eduardo Thadeu de Oliveira Correia,Letícia Mara Dos Santos Barbetta,João Paulo Chevrand Latini de Almeida et al.
Eduardo Thadeu de Oliveira Correia et al.
Anakinra is a recombinant human interleukin 1 receptor antagonist that competes and blocks the biologic effects of interleukin 1, reducing systemic inflammatory responses. In the 2015 guidelines for the diagnosis and management of pericardi...
Hydrogen Protons Modulate Perivascular Axo-axonal Interactions in the Middle Cerebral Artery of Rats [0.03%]
氢质子调节大鼠大脑中动脉周围轴突与轴突的相互作用
Kuo-Feng Huang,Hsi-Hsien Chang,Cheng-Hsing Hsieh et al.
Kuo-Feng Huang et al.
Previous studies have demonstrated that nicotine can induce relaxation of the middle cerebral artery (MCA). However, whether this relaxation is associated with the activity of sensory calcitonin gene-related peptide (CGRP) nerves and whethe...
Systematic Review and Meta-analysis Appraising Efficacy and Safety of Vernakalant for Cardioversion of Recent-Onset Atrial Fibrillation [0.03%]
评估 Vernakalant 转复近期发作的房颤有效性和安全性的系统评价和 meta 分析
Wenfang Ma,Xiying Guo,Qixian Wang et al.
Wenfang Ma et al.
Vernakalant is a novel, relatively atrial-selective antiarrhythmic agent. Despite its good efficacy profile and rapid onset of action, there was still controversial evidence regarding vernakalant-related adverse events. We searched PubMed a...
Cardioprotective Effects of Latifolin Against Doxorubicin-Induced Cardiotoxicity by Macrophage Polarization in Mice [0.03%]
莱替佛林通过小鼠巨噬细胞极化对抗多柔比星心毒性的保护作用研究
Ni Zhang,Binyao Shou,Lanying Chen et al.
Ni Zhang et al.
Latifolin, one of the major flavonoids extracted from lignum dalbergiae odoriferae, has been documented to protect the heart from acute myocardial ischemia induced by pituitrin and isoproterenol in rats and has also been found to inhibit in...
Rosuvastatin Reverses Hypertension-Induced Changes in the Aorta Structure and Endothelium-Dependent Relaxation in Rats Through Suppression of Apoptosis and Inflammation [0.03%]
rosuvastatin通过抑制凋亡和炎症逆转高血压引起的主动脉结构和内皮依赖性松弛的变化
Qingbo Lv,Yao Wang,Ya Li et al.
Qingbo Lv et al.
Vascular remodeling is one of the most critical complications caused by hypertension. Previous studies have demonstrated that rosuvastatin has anti-inflammatory, antioxidant, and antiplatelet effects and therefore can be used to treat cardi...
The mKATP Channels and protein-kinase C Are Involved in the Cardioprotective Effects of Genistein on Estrogen-Deficient Rat Hearts Exposed to Ischemia/Reperfusion: Energetic Study [0.03%]
雌激素缺乏的心肌缺血再灌注损伤大鼠模型中，染料木素心脏保护作用的线粒体研究及机制探讨
Germán A Colareda,María Inés Ragone,Patricia Bonazzola et al.
Germán A Colareda et al.
Estrogenic deficiency is considered a risk of coronary disease in women. The phytoestrogen genistein could be a safe preventive strategy. The first aim of this work was to validate a model of cardiac stunning in which natural estrogenic def...
Inhibition of GPR35 Preserves Mitochondrial Function After Myocardial Infarction by Targeting Calpain 1/2 [0.03%]
GPR35抑制通过靶向钙蛋白酶1/2保护心肌梗死后线粒体功能
Ken Chen,Lei He,Yong Li et al.
Ken Chen et al.
Ischemia and anoxia-induced mitochondrial impairment may be a key factor leading to heart injury during myocardial infarction (MI). Calpain 1 and 2 are involved in the MI-induced mitochondria injury. G protein-coupled receptor 35 (GPR35) co...
Direct Oral Anticoagulants for the Treatment of Left Ventricular Thrombus-A New Indication? A Meta-summary of Case Reports [0.03%]
直接口服抗凝药物治疗左心室血栓的一项新适应症？病例报告的meta总结
Daniela Tomasoni,Edoardo Sciatti,Andrea Bonelli et al.
Daniela Tomasoni et al.
Left ventricular thrombus (LVT) can be a consequence of cardiac diseases such as heart failure with reduced ejection fraction and acute myocardial infarction. Currently, the guidelines recommend the use of warfarin for the treatment of this...
Rian/miR-210-3p/Nfkb1 Feedback Loop Promotes Hypoxia-Induced Cell Apoptosis in Myocardial Infarction Through Deactivating the PI3K/Akt Signaling Pathway [0.03%]
里安/ miR-210-3p/NFκB1反馈回路通过去活化PI3K/Akt信号通路促进心肌梗死缺氧诱导的细胞凋亡
Lihua Zhong,Jing Jia,Guohui Ye
Lihua Zhong
Myocardial infarction (MI) is a severe disease that could lead to reversible or irreversible ischemic heart damage. A previous study has revealed that microRNA mmu-miR-210-3p expression is downregulated in fat-1 transgenic mice post-MI. Nev...
Preventive Beneficial Effect of an Aqueous Extract of Phyllanthus amarus Schum. and Thonn. (Euphorbiaceae) on DOCA-Salt-Induced Hypertension, Cardiac Hypertrophy and Dysfunction, and Endothelial Dysfunction in Rats [0.03%]
用Phyllanthus amarus Schum.和Thonn.水提取物预防DOCA盐诱导的高血压，心肌肥厚及功能障碍，内皮功能障碍的小鼠模型中的阳性结果研究
N&#x;guessan Alain Yao,Zahid Rasul Niazi,Iveta Najmanová et al.
N&#x;guessan Alain Yao et al.
This study investigated the preventive effect of an aqueous extract of the whole plant of Phyllanthus amarus (AEPA) on blood pressure, cardiac, and endothelial function in the deoxycorticosterone acetate (DOCA) salt-induced hypertensive rat...