Thrombocytopenia During Prostacyclin Analogue Therapies of Pulmonary Arterial Hypertension-Possible Pathomechanisms and Implications [0.03%]
肺动脉高压类前列环素类似物治疗中的血小板减少症:可能的病理机制和意义
Grzegorz Grześk,Danuta Karasek,Mateusz Kusiak
Grzegorz Grześk
Pulmonary arterial hypertension is a quite rare, but problematic disease in everyday cardiologists' practice. Prostanoids are the most important group of drugs used in this disease. One of the biggest problems encountered during treatment w...
Thrombocytopenia During Prostacyclin Analogue Therapies of Pulmonary Arterial Hypertension-Possible Pathomechanisms and Implications [0.03%]
肺动脉高压类前列环素类似物治疗中的血小板减少症-可能的病理机制及影响
Grzegorz Grześk,Danuta Karasek,Mateusz Kusiak
Grzegorz Grześk
Pulmonary arterial hypertension is a quite rare, but problematic disease in everyday cardiologists' practice. Prostanoids are the most important group of drugs used in this disease. One of the biggest problems encountered during treatment w...
PCSK9 Inhibitors in Secondary Prevention-An Opportunity for Personalized Therapy [0.03%]
PCSK9抑制剂在二级预防中的作用——实施个性化治疗的机会
Chase Board,Michael S Kelly,Michael D Shapiro et al.
Chase Board et al.
Atherosclerotic cardiovascular disease (ASCVD) remains the leading cause of death worldwide. Low-density lipoprotein cholesterol (LDL-C) is the primary cause of ASCVD and reducing LDL-C levels with statin therapy significantly reduces ASCVD...
PCSK9 Inhibitors in Secondary Prevention-An Opportunity for Personalized Therapy [0.03%]
用于二级预防的PCSK9抑制剂——实施个性化治疗的机会
Chase Board,Michael S Kelly,Michael D Shapiro et al.
Chase Board et al.
Atherosclerotic cardiovascular disease (ASCVD) remains the leading cause of death worldwide. Low-density lipoprotein cholesterol (LDL-C) is the primary cause of ASCVD and reducing LDL-C levels with statin therapy significantly reduces ASCVD...
Resveratrol Attenuates Aortic Dissection by Increasing Endothelial Barrier Function Through the SIRT1 Pathway [0.03%]
白藜芦醇通过SIRT1信号通路增强内皮屏障功能以改善主动脉夹层
Kaijie Wang,Jinping Zhao,Wenwen Zhang et al.
Kaijie Wang et al.
Aortic dissection (AD) is a serious condition and a health issue on a global scale. β-Aminopropionitrile-induced AD in mice is similar to the pathogenesis of AD in humans. Resveratrol (RSV) is a natural polyphenolic substance that provides...
Effect of High Homocysteine Level on the Severity of Coronary Heart Disease and Prognosis After Stent Implantation [0.03%]
高同型半胱氨酸血症对冠心病严重程度及支架植入术后预后的影响
Shanshan Li,Liping Sun,Liqun Qi et al.
Shanshan Li et al.
Objectives: To determine the effect of high homocysteine (HCY) levels on the severity of coronary artery disease and prognosis after stent implantation. M...
Cardiovascular Pharmacology in the Time of COVID-19: A Focus on Angiotensin-Converting Enzyme 2 [0.03%]
新冠肺炎时代的心血管药理学:关注血管紧张素转换酶2
Leo F Buckley,Judy W M Cheng,Akshay Desai
Leo F Buckley
Coronavirus disease-2019 (COVID-19) has emerged as a pandemic affecting millions of adults. Severe acute respiratory syndrome coronavirus-2019 (SARS-CoV-2), the causative virus of COVID-19, infects host cells through angiotensin-converting ...
Cardiovascular Considerations in Treating Patients With Coronavirus Disease 2019 (COVID-19) [0.03%]
冠状病毒病(COVID-19)患者治疗中的心血管问题考虑因素
Dave L Dixon,Benjamin W Van Tassell,Alessandra Vecchié et al.
Dave L Dixon et al.
A novel betacoronavirus, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has spread rapidly across the globe since December 2019. Coronavirus disease 2019 (COVID-19) has a significantly higher mortality rate than seasonal infl...
Long Noncoding RNA XIST/miR-17/PTEN Axis Modulates the Proliferation and Apoptosis of Vascular Smooth Muscle Cells to Affect Stanford Type A Aortic Dissection [0.03%]
长非编码RNA XIST/miR-17/PTEN轴通过调节血管平滑肌细胞增殖和凋亡影响Stanford A型主动脉夹层发病发展的作用及机制研究
Xiaoyun Zhang,Hongyu Wu,Changjiang Mai et al.
Xiaoyun Zhang et al.
Stanford type A aortic dissection (TAAD) is one of the most lethal cardiovascular diseases with an extremely high morbidity and mortality rate. LncRNA X-inactive specific transcript (XIST) is abundantly expressed in human thoracic aortic di...
LRP1 and APOA1 Polymorphisms: Impact on Warfarin International Normalized Ratio-Related Phenotypes [0.03%]
低密度脂蛋白受体相关蛋白1和载脂蛋白A1多态性与华法林相关国际标准化比值表型的影响关系研究
Dan Li,Zhi-Ying Luo,Yi Chen et al.
Dan Li et al.
Warfarin international normalized ratio (INR)-related phenotypes such as the percentage of INR time in the therapeutic range (PTTR) and INR variability are associated with warfarin adverse reactions. However, INR-related phenotypes greatly ...