Levosimendan Efficacy and Safety: 20 Years of SIMDAX in Clinical Use [0.03%]
莱沃西坦的疗效和安全性：SIMDAX临床应用20年的经验
Zoltán Papp,Piergiuseppe Agostoni,Julian Alvarez et al.
Zoltán Papp et al.
Levosimendan was first approved for clinical use in 2000, when authorization was granted by Swedish regulatory authorities for the hemodynamic stabilization of patients with acutely decompensated chronic heart failure (HF). In the ensuing 2...
Magnesium Sulfate Administration in Moderate Coronary Artery Disease Patients Improves Atherosclerotic Risk Factors: A Double-Blind Clinical Trial Study [0.03%]
硫酸镁治疗中度冠心病患者可改善动脉粥样硬化危险因素：一项双盲临床试验研究
Hossein Farshidi,Ali R Sobhani,Mahdiye Eslami et al.
Hossein Farshidi et al.
Magnesium (Mg) deficiency is known to promote vascular and cardiac dysfunctions such as atherosclerosis. This study investigated the effect of oral MgSO4 therapy to improve lipid profile and serum oxidized LDL level and its receptor (LOX1) ...
Randomized Controlled Trial
Journal of cardiovascular pharmacology. 2020 Sep;76(3):321-328. DOI:10.1097/FJC.0000000000000874 2020
LncRNA Gm4419 Regulates Myocardial Ischemia/Reperfusion Injury Through Targeting the miR-682/TRAF3 Axis [0.03%]
长链非编码RNA Gm4419通过靶向miR-682/TRAF3轴调节心肌缺血再灌注损伤
Guixiang Zhao,Juledezi Hailati,Xiaoyun Ma et al.
Guixiang Zhao et al.
Myocardial cell death during acute myocardial infarction occurs because of acute ischemia, persistent ischemia, reperfusion-associated injury, and the inflammatory infiltrate as a response to cell necrosis. In the present study, quantitativ...
Prehospital Administration of Unfractionated Heparin in ST-Segment Elevation Myocardial Infarction Is Associated With Improved Long-Term Survival [0.03%]
急诊给药未分级肝素可改善ST段抬高心梗的长期生存率
Christopher McGinley,Ify R Mordi,Paul Kell et al.
Christopher McGinley et al.
Objective: Administration of unfractionated heparin to STEMI patients by the ambulance service is an established practice in Scotland, but the efficacy is unknown. We studied the effects of unfractionated heparin in STEMI...
Observational Study
Journal of cardiovascular pharmacology. 2020 Aug;76(2):159-163. DOI:10.1097/FJC.0000000000000865 2020
CEACAM1 Inhibited IκB-α/NF-κB Signal Pathway Via Targeting MMP-9/TIMP-1 Axis in Diabetic Atherosclerosis [0.03%]
CEACAM1通过靶向MMP-9 / TIMP-1轴抑制I kappa B-α / NF-κB信号通路在糖尿病动脉粥样硬化中的作用
Jie Yu,Guihu Sun,Yu Chen et al.
Jie Yu et al.
Atherosclerosis (AS) is the most common and serious complication in type 2 diabetes mellitus (T2DM). Recent studies have emphasized that inflammation is the main cause of atherosclerosis. Studies have shown that carcinoembryonic antigen-rel...
Low-Dose Ticagrelor in Patients With High Ischemic Risk and Previous Myocardial Infarction: A Multicenter Prospective Real-World Observational Study [0.03%]
高缺血风险既往心梗患者使用小剂量替格瑞洛的疗效与安全性：一项多中心前瞻性真实世界观察研究
Arturo Cesaro,Vittorio Taglialatela,Felice Gragnano et al.
Arturo Cesaro et al.
Prolonged dual antiplatelet therapy after 12 months in patients with previous myocardial infarction (MI) is attractive to reduce long-term ischemic complications. In the PEGASUS-TIMI 54, the use of low-dose ticagrelor (60 mg b.i.d.) plus as...
Observational Study
Journal of cardiovascular pharmacology. 2020 Aug;76(2):173-180. DOI:10.1097/FJC.0000000000000856 2020
Antihyperglycemic Therapies With Expansions of US Food and Drug Administration Indications to Reduce Cardiovascular Events: Prescribing Patterns Within an Academic Medical Center [0.03%]
心血管事件抗高血糖疗法的美国食品药品管理局指征扩展：学术医疗机构中的用药模式分析
Arsalan Hamid,Muthiah Vaduganathan,Adebamike A Oshunbade et al.
Arsalan Hamid et al.
Sodium-glucose cotransport protein-2 inhibitors (SGLT2is) and glucagon-like peptide-1 receptor agonists (GLP-1RAs) have been shown to reduce cardiovascular events in high-risk patients with type 2 diabetes mellitus (T2DM). We examined real-...
Effects of Dual Purinoceptor-dependent Approach on Release of Vascular Endothelial Growth Factor From Human Microvascular Endothelial Cell (HMEC-1) and Endothelial Cell Condition [0.03%]
双腺苷酸受体依赖性途径对人微血管内皮细胞血管内皮生长因子释放及内皮细胞功能的影响
Anna M Gdula,Maria Swiatkowska
Anna M Gdula
In the recent years, the awareness of the role purinergic signaling plays as a therapeutic target has increased considerably. The purinoceptor allows the action of extracellular nucleotides (P2 receptors) and intermediary products of their ...
Deciphering the Mechanisms Behind Cardiovascular Disease: Long Noncoding RNAs as Key Molecular Signaling Hubs and Biomarkers of Atherosclerosis [0.03%]
阐明心血管疾病机制：长链非编码RNA作为动脉粥样硬化关键分子信号中心及生物标志物
Nastassia Navasiolava,Bernard Degryse,Marc-Antoine Custaud et al.
Nastassia Navasiolava et al.
Elizabeth M Gavioli,Gabriela Sikorska,Ammy Man et al.
Elizabeth M Gavioli et al.
Thromboembolism and myocardial injury is common in patients with COVID-19. Low-molecular-weight heparin appears to be associated with a good prognosis in patients with COVID-19 and has the ability to reduce coagulation and inflammation mark...