Chemokine (C-C motif) Ligand 6 Aggravates Hypoxia Reoxygenation-induced Apoptosis in H9c2 Cells Through Enhancing the Expression of Insulin-like Growth Factor 2-Antisense [0.03%]
趋化因子(C-C模体)配体6通过增强相似生长因子2-反义链的表达加重H9c2细胞低氧再复氧诱导的凋亡
Xiufen Li,Bilali Aishan,Yan Yang et al.
Xiufen Li et al.
Chemokine (C-C motif) ligand 6 (CCL6), one of the small cytokines in the CC chemokine family, has been reported to involve in renal ischemia-reperfusion (I/R) injury. However, the role of CCL-6 in myocardial I/R injury is nonelucidated. In ...
Resveratrol Stimulates the Na+-Ca2+ Exchanger on the Plasma Membrane to Reduce Cytosolic Ca2+ in Rat Aortic Smooth Muscle Cells [0.03%]
白藜芦醇通过激活大鼠主动脉平滑肌细胞的Na+-Ca2+交换蛋白来降低胞浆钙离子浓度
Fuman Yan,Jun Lu,Yunting Zhang et al.
Fuman Yan et al.
Resveratrol is well known to exhibit vascular relaxant and antihypertensive effects. In this study, we determined the effects of resveratrol on the modulation of cytosolic [Ca] level and adenosine 5'-triphosphate-induced Ca release from the...
MiR-455-5p Attenuates Cerebral Ischemic Reperfusion Injury by Targeting FLT3 [0.03%]
miR-455-5p通过靶向FLT3减轻脑缺血再灌注损伤
Jinjing Chen,Chunran Zhu,Weijian Jia et al.
Jinjing Chen et al.
Cerebral ischemia-reperfusion (I/R) injury is a terrible disease which results in the dysfunction and structural damage of brain tissues. Growing evidence implies that miR-455-5p is implicated in the regulation of pathogenesis of several di...
Silencing of Long Noncoding RNA Zinc Finger Antisense 1 Protects Against Hypoxia/Reoxygenation-induced Injury in HL-1 Cells Through Targeting the miR-761/Cell Death Inducing p53 Target 1 Axis [0.03%]
长链非编码RNA锌指反义1的沉默通过靶向miR-761/诱导p53靶标1轴保护HL-1细胞免受缺氧/复氧引起的损伤
Xiaojun Xiang,Lei Zheng,Xuewen Li
Xiaojun Xiang
Acute myocardial infarction (AMI) is a major cause of morbidity and mortality worldwide. Long noncoding RNAs have demonstrated to be associated with AMI pathogenesis. In this study, we aimed to investigate the function and mechanism of zinc...
Long Noncoding RNA Taurine-Upregulated Gene 1 Knockdown Protects Cardiomyocytes Against Hypoxia/Reoxygenation-induced Injury Through Regulating miR-532-5p/Sox8 Axis [0.03%]
长链非编码RNA牛磺酸上调基因1通过调节miR-532-5p / Sox8轴保护心肌细胞免受缺氧/复氧诱导的损伤
Xinyong Cai,Shu Wang,Lang Hong et al.
Xinyong Cai et al.
Background: Long noncoding RNA taurine-upregulated gene 1 (TUG1) has been reported to involve in the processing of cardiac ischemia/reperfusion injury after myocardial infarction. Thus, this study further investigates the...
Long Noncoding RNA OIP5-AS1 Contributes to the Progression of Atherosclerosis by Targeting miR-26a-5p Through the AKT/NF-κB Pathway [0.03%]
长链非编码RNA OIP5-AS1通过靶向miR-26a-5p及AKT/NF-κB通路促进动脉粥样硬化进展
Mingming Ren,Tao Wang,Zhen Han et al.
Mingming Ren et al.
Atherosclerosis (AS) is a cardiovascular disease caused by multiple factors, leading to high mortality and morbidity in aged people. Some long noncoding RNAs have been reported to be associated with AS progression. However, the roles of OIP...
Clinical Conundrum: Three Management Strategies for Three-Vessel Coronary Artery Disease? [0.03%]
临床困惑：三支冠脉疾病的三种治疗策略？
Giuseppe Biondi-Zoccai,Giacomo Frati,Fabio Miraldi et al.
Giuseppe Biondi-Zoccai et al.
Choosing Wisely: Cardiovascular Drug Therapy in the Era of COVID-19 [0.03%]
明智选择：COVID-19疫情时代的心血管药物治疗
Peter Nordbeck,Kai Hu
Peter Nordbeck
SUPPORT-1 (Subjects Undergoing PCI and Perioperative Reperfusion Treatment): A Prospective, Randomized Trial of CMX-2043 in Patients Undergoing Elective Percutaneous Coronary Intervention [0.03%]
支持-1（接受经皮冠状动脉介入治疗的患者和围手术期再灌注治疗）：在择期经皮冠状动脉介入治疗患者中进行CMX-2043的前瞻性随机试验
James E Tcheng,Michael Gibson,Mitchell W Krucoff et al.
James E Tcheng et al.
Objective: The natural molecule α-lipoic acid has been shown to be partially cytoprotective through antioxidant and antiapoptotic mechanisms. To obtain an initial assessment of the safety and potential efficacy of a synt...
The Controversy of Renin-Angiotensin-System Blocker Facilitation Versus Countering COVID-19 Infection [0.03%]
肾素血管紧张素系统阻滞剂与COVID-19感染促进与抑制的争议
Antonis S Manolis,Theodora A Manolis,Antonis A Manolis et al.
Antonis S Manolis et al.
The ongoing COVID-19 pandemic has produced serious turmoil world-wide. Lung injury causing acute respiratory distress syndrome seems to be a most dreaded complication occurring in ∼30%. Older patients with cardiovascular comorbidities and ...