Metabolic dysregulation of hydrogen sulfide as a driver of vascular disease [0.03%]
代谢氢硫酸盐失调在血管疾病中的驱动作用
Alexander E Berezin
Alexander E Berezin
Contractile Effects of Histamine in Mice Overexpressing H1-Histamine and H2-Histamine Receptors in the Atrium [0.03%]
心房过表达H1组胺和H2组胺受体小鼠的收缩效应研究
Thanh Hoai Pham,Lina Maria Rayo Abella,Igor Buchwalow et al.
Thanh Hoai Pham et al.
To identify the functional roles of human H1-histamine and H2-histamine receptors when they coexist in the heart, we crossbred mice that overexpressed human H1-histamine receptors only in the heart (H1-TG) with mice that overexpressed human...
Effect of HDAC4 regulation of β-catenin signaling pathway on cardiac injury in spontaneously hypertensive rats and its mechanism [0.03%]
HDAC4调控β-catenin信号通路对 SHR心肌损伤的影响及机制研究
Ping Liu,Zhaohui Meng,Lei Zhang et al.
Ping Liu et al.
HDAC4 is highly expressed in patients with essential hypertension and is closely related to myocardial injury. Therefore, this study aims to explore the effects and mechanisms of HDAC4 on cardiac injury in spontaneously hypertensive rats, w...
Preventing Contrast-Associated Acute Kidney Injury: Does the Choice of Statin Matter? [0.03%]
他汀类药物预防对比剂相关急性肾损伤的作用及不同类型他汀的选择？
Anastasios Apostolos
Anastasios Apostolos
Aerobic exercise rehabilitation training alleviates skeletal muscle atrophy caused by heart failure in mice through the SIRT1/PGC-1α pathway [0.03%]
有氧运动康复训练通过SIRT1/PGC-1α通路缓解心力衰竭小鼠骨骼肌萎缩
Jiawei Zhang,Xiao Chen,Chunxiao Wan
Jiawei Zhang
To investigate the potential effects of aerobic exercise rehabilitation training (AET) on the progression of myocardial infarction (MI) in a left anterior descending (LAD) coronary artery ligation model in mice, and to explore the underlyin...
ETS1-THBS1 Axis Regulates Macrophage Polarization and Exacerbates Myocardial Injury in Diabetic Cardiomyopathy [0.03%]
ETS1-THBS1轴调节巨噬细胞极化并加重糖尿病心肌病中的心肌损伤
Xinbin Wang,Guligena Sawuer,Cheng Liang et al.
Xinbin Wang et al.
Diabetic cardiomyopathy (DCM) is a major complication of diabetes marked by myocardial dysfunction, inflammation, and fibrosis. Immune cell infiltration and macrophage polarization are critical in DCM progression. This study examined the ro...
The therapeutic potential of hydrogen sulfide and its donors, a new discovery in vascular diseases [0.03%]
血管疾病治疗的新希望——氢硫化物及其供体的治疗潜力
Youzhen Pu,Wenlong Lin,Suyi Ren et al.
Youzhen Pu et al.
Hydrogen sulfide (H2S), an important gaseous signaling molecule, plays a critical role in maintaining vascular homeostasis. H2S participates in numerous biological functions, including redox regulation, interactions with other signaling mol...
TRPV4-dependent signaling pathways play essential regulatory roles in high salt-induced cardiac hypertrophy via autophagic alterations [0.03%]
TRPV4依赖的信号通路通过自噬改变在高盐诱导的心肌肥厚中起重要作用
Yin Li,Rui Xu,Yuanteng Zhang et al.
Yin Li et al.
Cardiac hypertrophy, initially referred to as an adaptive response, would gradually transit to decompensated states over time, contributing to hypertension, and ultimately heart failure under salt overload. The cellular and molecular mechan...
Bleomycin for Malignant Pericardial Effusion: A Systematic Review of Efficacy and Adverse Events [0.03%]
博莱霉素治疗恶性心包积液的疗效和不良事件的系统评价
Paulus Parholong Siahaan,Roy Bagus Kurniawan,Pandit Bagus Tri Saputra et al.
Paulus Parholong Siahaan et al.
Malignant pericardial effusion (MPE) is a progressive fluid accumulation in the pericardial space that can lead to pericardial tamponade. Despite the high recurrence rate associated with pericardiocentesis, it remains the mainstay therapy. ...
Comparison of short-term treatment with atorvastatin versus rosuvastatin for preventing contrast-associated acute kidney injury in patients undergoing coronary angiography/percutaneous coronary intervention: a systematic review and meta-analysis [0.03%]
阿托伐他汀与罗苏伐他汀短期治疗用于接受冠状动脉造影/经皮冠状动脉介入治疗患者的对比以预防对比剂相关急性肾损伤：一项系统综述和meta分析
Mansour Bahardoust,Danyal Yarahmadi,Zahra Aghakhani et al.
Mansour Bahardoust et al.
The effect of atorvastatin compared with rosuvastatin on the prevention of contrast-associated acute kidney injury (CA-AKI) after percutaneous coronary intervention (PCI) has been heterogeneous in different studies, which may be due to the ...