Molecular Mechanisms of Felodipine Suppressing Atherosclerosis in High-Cholesterol-Diet Apolipoprotein E-Knockout Mice: Erratum [0.03%]
氟桂利嗪抑制高胆固醇饮食Apoe基因敲除小鼠动脉粥样硬化分子机制的研究-勘误
Rui Yao,Xiang Cheng,Yu-Hua Liao et al.
Rui Yao et al.
Efficacy and Safety of Oral PCSK9 Inhibitors in Adults with Hypercholesterolemia: A Systematic Review and Meta-Analysis of Randomized Controlled Trials [0.03%]
口服PCSK9抑制剂治疗高胆固醇血症成人患者的有效性和安全性：随机对照试验的系统综述和meta分析
Amna Amir Jalal,Syed Ibad Hussain,Erum Siddiqui et al.
Amna Amir Jalal et al.
Injectable PCSK9 inhibitors effectively lower LDL-C levels in patients with hypercholesterolemia; however, their high cost and requirement for parenteral administration limit their widespread use. Oral PCSK9 inhibitors have emerged as a con...
Lipid-Lowering Efficacy and Adverse Events of CETP Inhibitor Combination Therapy: A Systematic Review and Network Meta-Analysis [0.03%]
胆固醇酯转运蛋白抑制剂联合治疗的降脂疗效及不良反应：系统评价和网络 meta 分析
Ping Guo,Xinlin Yu,Xinxin Wei et al.
Ping Guo et al.
Background: The therapeutic effects of different combination therapies containing cholesteryl ester transfer protein (CETP) inhibitors vary. Evidence from head-to-head comparisons is scarce and inconsistent. This study ai...
Individualized Cardiovascular Therapeutics via Artificial Intelligence-Powered Cardiovascular Imaging [0.03%]
人工智能赋能的心血管影像个体化心血管治疗
Oluwaremilekun Zeth Tolu-Akinnawo,Andrew Greek,Dania Jaamour et al.
Oluwaremilekun Zeth Tolu-Akinnawo et al.
Cardiovascular disease remains a leading cause of global illness and death, accounting for approximately 17.9 million deaths annually, according to the World Health Organization. There is a growing need for more precise and individualized t...
Colchicine for Major Adverse Cardiovascular Events: An Updated ChatGPT-Assisted Systematic Review and Meta-Analysis [0.03%]
秋水仙碱预防重大不良心血管事件的更新系统评价和 meta 分析
Lefteris Teperikidis,Aristi Boulmpou,Manisha Chownk et al.
Lefteris Teperikidis et al.
Colchicine has been studied as an anti-inflammatory treatment for cardiovascular prevention, but findings from randomized trials have been inconsistent. This meta-analysis evaluated the efficacy and safety of colchicine in reducing major ad...
Direct Oral Anticoagulants versus Warfarin on Coronary Plaque in Atrial Fibrillation: A Meta-Analysis of Randomized Controlled Trials [0.03%]
直接口服抗凝剂与华法林对房颤患者冠状动脉斑块的影响：随机对照试验的meta分析
Lucas M Barbosa,Vinícius Martins Rodrigues Oliveira,Maria do Carmo P Nunes et al.
Lucas M Barbosa et al.
Warfarin inhibits vitamin K-dependent proteins that prevent vascular calcification. We hypothesized that direct oral anticoagulants (DOACs), which do not interact with vitamin K, would slow coronary plaque progression compared to warfarin i...
Evaluation and management of treatment failure and non-response to cardiac myosin inhibitors in obstructive hypertrophic cardiomyopathy [0.03%]
梗阻性肥厚型心肌病心脏肌球蛋白抑制剂治疗失败和无反应的评估与处理
Myra Lewontin,Yaqub Betz,Jamey Cutts et al.
Myra Lewontin et al.
The recent emergence of cardiac myosin inhibitors (CMIs) has established an era of targeted medical therapy for obstructive hypertrophic cardiomyopathy (oHCM), with trials showing decreases in obstructive gradients and improvements in sympt...
Effect of Vericiguat on Pulmonary Artery Pressures in Heart Failure Patients: Real-World Insights from Pressure Sensor Monitoring [0.03%]
用于心力衰竭患者肺动脉压的VERICIGUAT疗效：压力传感器监测的真实世界见解
Boaz Elad,Dor Lotan,Ilan Richter et al.
Boaz Elad et al.
Vericiguat improves outcomes in heart failure (HF) by promoting vasodilation of the systemic and pulmonary arterial beds. Little is known about its impact on pulmonary artery pressure (PAP). We aimed to study this effect using measurements ...
Ivabradine as a treatment for postural orthostatic tachycardia syndrome: A systematic review [0.03%]
伊伐布雷定治疗体位性心动过速综合征的系统评价
Chun Shing Kwok,David Gillespie,Naeem Ur Rehman Qazi et al.
Chun Shing Kwok et al.
Ivabradine is one of several off-label treatments for patients with postural orthostatic tachycardia syndrome (POTS). We conducted a systematic review of the literature to identify studies which evaluate ivabradine treatment in patients wit...
Vasodilatory effects of trans-3-methoxy-β-nitrostyrene, a synthetic nitroderivative, on rat thoracic aorta: involvement of soluble guanylate cyclase stimulation [0.03%]
一种合成硝基衍生物反式-3-甲氧基-β-亚硝基 stilbene 对大鼠胸主动脉的血管舒张作用：可溶性鸟苷酸环化酶介导的信号转导途径参与其中
Yeimer Antonio Santiago Guevara,Alefe Islleyker Aguiar Santiago,Lucas Rodrigues Melo et al.
Yeimer Antonio Santiago Guevara et al.
Previously, we showed that vasorelaxant effects of trans-4-methoxy-β-nitrostyrene (T4MN) in rat aorta were mediated through stimulation of the soluble guanylate cyclase (sGC) pathway. The present study tested the hypothesis that bonding of...