Immunotoxicology From a Pathology Perspective: A Continuing Education Course Presented at the Annual STP Meeting in Baltimore, MD, Held June 16-19, 2024 [0.03%]
从病理学角度探讨免疫毒理学：在美国马里兰州巴尔的摩举行的年度STP会议（时间为2024年6月16日至19日）上呈现的继续教育课程
Tracey L Papenfuss,Ashwini Phadnis Moghe,Lauren E Himmel et al.
Tracey L Papenfuss et al.
This article is a summary of a half-day continuing education course jointly sponsored by the Society for Toxicologic Pathology (STP) and the Health and Environmental Sciences Institute (HESI) at the annual meeting of the STP in Baltimore, M...
Toxicologic Pathology Forum*: Opinion on New Technologies and Trends Disrupting Drug Discovery and Development: How Can the Next Generation of Toxicologic Pathologists Be Prepared for Evolving Roles? [0.03%]
毒理病理学论坛*：对颠覆药物研发的新技术和趋势的意见：如何为毒理病理学家角色的转变做好准备？
Rebecca Kohnken,Lauren Himmel,Magali Guffroy et al.
Rebecca Kohnken et al.
The pace of technological innovation in the pharmaceutical industry, like in many other sectors, is accelerating rapidly. This is not only reshaping how pharmaceutical Research and Development (R&D) is conducted (e.g., introduction of novel...
Interpretative Challenges in Animal Studies: Review of Case Studies and Implications for Toxicologic Pathology [0.03%]
动物研究中的诠释挑战：案例研究回顾及其对毒性病理学的影响
Ruba Ibrahim,Abraham Nyska,Susan A Elmore et al.
Ruba Ibrahim et al.
Toxicologic pathologists play a crucial role in the evaluation of animal studies for drugs, environmental chemicals, medical devices, and other agents to determine their safety and potential toxic effects. A significant challenge in this do...
Mini Review: Spatial Transcriptomics to Decode the Central Nervous System [0.03%]
迷你综述：空间转录组学在解码中枢神经系统中的应用
Benedek Pesti,Xavi Langa,Nadine Kumpesa et al.
Benedek Pesti et al.
Spatial transcriptomics (ST) is revolutionizing our understanding of the central nervous system (CNS) by providing spatially resolved gene expression data. This mini review explores the impact of ST on CNS research, particularly in neurodeg...
Scientific and Regulatory Policy Committee Points to Consider* for Determining and Reporting Cause of Death/Moribundity in Non-Rodent Species in Toxicity Studies [0.03%]
毒性研究中确定和报告非啮齿类动物死亡/濒死原因的科学与法规政策委员会需考虑的因素*
Karyn Colman,Kathleen A Funk,Michael Boyle et al.
Karyn Colman et al.
The Cause of Death in Non-Rodents (CODN) Working Group is an initiative under the Scientific and Regulatory Policy Committee (SRPC) of the Society of Toxicologic Pathology (STP), focused on understanding existing practices and expectations ...
Proceedings of the 2023 Annual Scientific Meeting of the French Society of Toxicologic Pathology (SFPT) on Preclinical Development and Therapeutic Applications of mRNA-Based Technologies [0.03%]
2023年法国毒理病理学会年度科学会议关于基于mRNA技术的临床前开发和治疗应用的论文集
Pierluigi Fant,Sébastien Laurent,Paul Desert et al.
Pierluigi Fant et al.
The 2023 annual scientific meeting of the French Society of Toxicologic Pathology (Société Française de Pathologie Toxicologique, SFPT), entitled "mRNA-based technologies: preclinical development and therapeutic applications," was held i...
Corrigendum to Toxicologic Pathology Forum: Opinion on Performing Good Laboratory Practice Histopathology Evaluation for Nonclinical Toxicity Studies in a Remote Location [0.03%]
毒理病理学论坛的勘误：对在远程位置进行良好实验室规范组织病理学评估的非临床毒性研究的意见
Published Erratum
Toxicologic pathology. 2025 Mar 18:1926233251322124. DOI:10.1177/01926233251322124 2025
Pierre Maliver,Julie Boisclair,Ingrid Pardo et al.
Pierre Maliver et al.
The last session of the 2024 European Society of Toxicologic Pathology Congress was dedicated to recent neuro concepts, encompassing various topics including artificial intelligence (AI) applied to toxicologic pathology, new technologies fo...
Case Report: Glioneuronal Hamartoma in the Cerebral Cortex of a Juvenile Cynomolgus Monkey (Macaca fascicularis) [0.03%]
病例报告：幼年猕猴(Macaca fascicularis)大脑皮层的胶质神经元畸形病病变
Elaine Debien,Felix Goulet,Lee Silverman et al.
Elaine Debien et al.
Two dark and raised foci were observed on the left hemisphere of the brain of a 3-year-old cynomolgus monkey during the routine necropsy procedures of a preclinical toxicity study. Microscopic examination revealed a lesion in the cerebral c...
Comparisons of the Sensitivity of Histopathological and Immunohistochemical Analyses With Blood Hormone Levels for Early Detection of Antithyroid Effects in Rats Treated With Promoters of Thyroid Hormone Metabolism [0.03%]
组化和免疫组化分析与血液激素水平对甲状腺素代谢促进剂导致的大鼠抗甲状腺效应早期检测的敏感性比较研究
Hirotoshi Akane,Takeshi Toyoda,Kohei Matsushita et al.
Hirotoshi Akane et al.
Although blood triiodothyronine (T3), thyroxine (T4), and thyroid-stimulating hormone (TSH) levels are useful for detecting antithyroid compounds in rodent toxicity studies, there are challenges with high variability due to sampling conditi...