Pediatric oncology [0.03%]
儿科肿瘤学
Andrew M Davidoff
Andrew M Davidoff
Cancer is a disease whose progression is driven by a series of accumulating genetic and epigenetic changes influenced by hereditary factors and the somatic environment. These changes result in individual cells acquiring a phenotype that pro...
Cryptorchidism [0.03%]
隐睾症
John M Hutson,Adam Balic,Tamara Nation et al.
John M Hutson et al.
Cryptorchidism is a very common anomaly of the male genitalia, affecting 2%-4% of male infants and is more common in premature infants. There are two separate stages of testicular descent. The first stage occurs at 8-15 weeks' gestation in ...
Thomas W Sadler
Thomas W Sadler
Ventral body wall defects include ectopia cordis, bladder exstrophy, and the abdominal wall malformations gastroschisis and omphalocele. The etiology of ectopia cordis, gastroschisis, and bladder exstrophy is not known, but they may be link...
Dietrich Kluth
Dietrich Kluth
Today, the normal and abnormal development of the hindgut is still a matter of speculation. However, as the result of recent studies in appropriate animal models, most embryologic events that finally lead to abnormal hindgut development are...
Hirschsprung's disease [0.03%]
赫什普룽病
Simon E Kenny,Paul K H Tam,Mercè Garcia-Barcelo
Simon E Kenny
Hirschsprung's disease (HSCR) is characterized by absence of the enteric nervous system in a variable portion of the distal gut. Affected infants usually present in the days after birth with bowel obstruction. Despite surgical advances, lon...
Yousef El-Gohary,George K Gittes,Juan A Tovar
Yousef El-Gohary
Congenital malformations of the esophagus are frequently encountered by pediatric surgeons, especially esophageal atresia with or without tracheo-esophageal fistula. However, the molecular mechanisms underlying the development of these vari...
Richard Keijzer,Prem Puri
Richard Keijzer
Congenital diaphragmatic hernia (CDH) is a congenital anomaly consisting of a posterolateral defect in the diaphragm also known as a Bochdalek hernia. It occurs in 1 in 2000 to 3000 newborns and is associated with a variable degree of pulmo...
Jorge Correia-Pinto,Sílvia Gonzaga,Yadi Huang et al.
Jorge Correia-Pinto et al.
Congenital lung lesions comprise a broad spectrum of rare but clinically significant developmental abnormalities, including congenital cystic adenomatoid malformation, bronchopulmonary sequestrations, congenital lobar emphysema, and broncho...
Richard Keijzer,Dick Tibboel
Richard Keijzer
Outcome of anorectal malformations and Hirschsprung's disease beyond childhood [0.03%]
有关肛门直肠畸形和先天性巨结肠病的成人期预后
Risto J Rintala,Mikko P Pakarinen
Risto J Rintala
Anorectal malformations (ARMs) and Hirschsprung disease (HD) are the most common congenital colorectal defects in the newborn. The outcomes of HD and ARMs have improved significantly because of improved understanding of the pathologic anato...