What should ethics guidelines look like for clinical trials of in utero stem cell, protein, mRNA, and gene therapies to treat fetal disease? [0.03%]
胎儿疾病宫内干细胞、蛋白质、mRNA和基因治疗临床试验的伦理指南应包括哪些内容？
Emily M Scire,Dario O Fauza
Emily M Scire
State-of-the-art minimally invasive in utero interventions involving stem cell, protein, and nucleic acid-based therapies represent a new frontier in medicine, which offers hope for devastating fetal diagnoses and promises the restoration o...
Emily M Scire,Dario O Fauza
Emily M Scire
Vikas S Gupta,Joseph T Church,Kevin N Johnson
Vikas S Gupta
Artificial intelligence for prediction and detection of pediatric surgical site infection [0.03%]
人工智能在儿童手术部位感染预测和检测中的应用
Andrew P Bain,Jeffrey S Upperman
Andrew P Bain
Surgical site infections (SSIs) remain a significant source of morbidity in pediatric surgery, prolonging hospital stays, increasing readmissions, and driving up healthcare costs. Manual chart reviews and static risk models limit traditiona...
Effects of caudal versus penile block on the incidence of hypospadias complications following primary repairs: A prospective, double-blind, randomized controlled trial [0.03%]
尾块与阴茎块对尿道下裂一期手术后并发症发生率影响的前瞻性双盲随机对照研究
Fikret Salık,Meral Erdal Erbatur,Mehmet Ali Turgut et al.
Fikret Salık et al.
Introduction: This prospective, randomized, double-blinded study aimed to compare the incidence of postoperative complications and perioperative analgesic efficacy between caudal and penile block in children undergoing pr...
Marcin Polok,Bernarda Kazanowska,Ewa Bień et al.
Marcin Polok et al.
Background: The aim of the study was an assessment of whether the age of patients with WT could be measured as a risk factor and an analysis of the treatment of patients over 10 years old. ...
Systematic review and meta-analysis of the effectiveness and safety of conservative versus surgical management in pediatric pancreatic trauma [0.03%]
儿童胰腺外伤保守治疗与手术治疗效果和安全性的系统评价和 Meta 分析
Mateo Londoño Barrientos,Sofia Pinzon Calderon,Carlos Alberto Lopez Zapata et al.
Mateo Londoño Barrientos et al.
Background: Pancreatic trauma in the pediatric population is an uncommon but highly morbid injury. Its management remains controversial, with treatment strategies ranging from non-operative management (NOM) to upfront ope...
Clinical outcome and risk factors for recurrence of percutaneous external drainage in treating pediatric pancreatic pseudocysts [0.03%]
儿科急性胰腺炎假性囊肿穿刺外引流的疗效及复发危险因素分析
Ken Chen,Shuhao Zhang,Qingjiang Chen
Ken Chen
Background: Pediatric pancreatic pseudocysts are rare clinically and there is no consensus on an optimum treatment strategy for it. Here, we aim to evaluate the outcome and efficacy of percutaneous external drainage in tr...
Tubo-ovarian abscess etiology, presentation, and management in youth and adolescents [0.03%]
青春期和青少年输卵管卵巢脓肿的病因、临床表现及处理措施
Garrett Garbo,Stephanie Cizek
Garrett Garbo
Tubo-ovarian abscesses (TOA) in children and adolescents may be missed or delayed in diagnosis due to differences in the etiologies, presentation, and clinical evaluation compared to adult patients. Management of TOA should include intraven...
Alexa G Turpin,Peter C Minneci,Charles N Paidas
Alexa G Turpin
Malignant ovarian tumors are exceedingly rare in children. The overwhelming majority of ovarian masses in the pediatric population are benign. Distinguishing benign from malignant ovarian pathology can be challenging. Avoidance of oophorect...