Allen Zhong,Kasper S Wang
Allen Zhong
Isabelle Lane Curran,Robert A Cowles
Isabelle Lane Curran
Biliary atresia can be a challenging diagnosis to make as there is no single definitive diagnostic laboratory or imaging study available and no single agreed upon diagnostic algorithm. The purpose of this article is to review the complex pu...
Iiris Nyholm,Maria Hukkinen,Mikko P Pakarinen
Iiris Nyholm
Regardless of the underlying etiology and success of PE, progressive liver fibrosis and eventually cirrhosis represent the dominant pathology and the end-stage of BA. Ascending bile duct injury-induced cholestasis, inflammation and ductular...
Renos M Jeropoulos,Jorge Arroyo,Mark Davenport
Renos M Jeropoulos
Biliary atresia (BA) remains a disease of significant morbidity and mortality world-wide. Early and accurate diagnosis facilitates early intervention and improves outcomes. The gold standard in diagnosing BA is a liver biopsy followed by ch...
Alyssa Stetson,Alexander Bondoc,Greg Tiao
Alyssa Stetson
The Kasai portoenterostomy (KPE) can provide a surgical cure for children with biliary atresia (BA), without the need for a liver transplant (OLTxp). Revision KPE can be attempted following a failed initial KPE where biliary clearance is no...
Post-Kasai cholangitis evaluation and management strategies: Review of the literature with insights from the Swiss Biliary Atresia Registry [0.03%]
卡塞伊胆管炎的术后评估和管理策略：文献回顾及瑞士胆道闭锁注册中心的见解
Ana M Calinescu,Barbara E Wildhaber
Ana M Calinescu
Cholangitis, defined as the inflammation of the bile ducts, is the most frequent complication after Kasai hepatoportoenterostomy in patients with biliary atresia (BA). This review seeks to provide a comprehensive synthesis of current knowle...
Genetics of biliary atresia: Approaches, pathological insights and challenges [0.03%]
胆道闭锁的遗传学：方法、病理学见解和挑战
Qiongfen Lin,Paul Kwong-Hang Tam,Clara Sze-Man Tang
Qiongfen Lin
Biliary atresia (BA) is a severe neonatal cholestatic disorder marked by fibro-obliteration of the extrahepatic and intrahepatic bile ducts. It is the most common cause of pediatric end-stage liver disease and the leading indication for liv...
Phoebe N Miller,Suruthi Baskaran,Amar Nijagal
Phoebe N Miller
Biliary atresia is a progressive neonatal cholangiopathy that leads to liver failure. Characterized by inflammation-mediated liver injury, the immune system plays a critical role in the pathogenesis of this disease. Though several types of ...
Carmen Mesas Burgos,Natalie Rintoul,Lars Mikael Broman
Carmen Mesas Burgos
Despite ECMO being a well-accepted and established life-saving support for newborns, prematurity ( 2.0 kg) deserves to be challenge. The authors suggest that Prem-ECMO (GA 32-33) could be considered when restricted to experienced high-volum...
Advancing pediatric anesthesia care: Insights and innovations for enhanced patient outcomes [0.03%]
推进儿科麻醉护理：提升患者预后的洞察与创新
Narasimhan Jagannathan,Amod Sawardekar
Narasimhan Jagannathan