Jonathan M Fishman,Mark Lowdell,Martin A Birchall
Jonathan M Fishman
Tissue engineering requires the use of cells seeded onto scaffolds, often in conjunction with bioactive molecules, to regenerate or replace tissues. Significant advances have been made in recent years within the fields of stem cell biology ...
Timothy J Keane,Stephen F Badylak
Timothy J Keane
With advancements in biological and engineering sciences, the definition of an ideal biomaterial has evolved over the past 50 years from a substance that is inert to one that has select bioinductive properties and integrates well with adjac...
Chao Zhang,Sean V Murphy,Anthony Atala
Chao Zhang
Repair and reconstruction of damaged tissues and organs has been a major issue in the medical field. Regenerative medicine and tissue engineering, as rapid evolving technologies, may offer alternative treatments and hope for patients with s...
Paolo De Coppi,T C Grikscheit
Paolo De Coppi
Gerard V Walls
Gerard V Walls
Multiple endocrine neoplasia (MEN) syndromes are characterised by the combined occurrence of two or more endocrine tumours in a patient. These autosomal dominant conditions occur in four types: MEN1 due to inactivating MEN1 mutations; MEN2A...
Paul R V Johnson
Paul R V Johnson
Neuroendocrine tumors (NETs) (previously termed carcinoids) are slow-growing tumors of the neuroendocrine system. They can occur anywhere within the body but are most commonly found in the midgut. This review is therefore confined to a disc...
Islet cell transplantation [0.03%]
胰岛细胞移植
Michael McCall,A M James Shapiro
Michael McCall
Islet transplantation has become a promising treatment for selected patients with type 1 diabetes. Here we provide an overview of the procedure including its history, the process of donor selection, and the techniques and procedures involve...
Pratik Shah,Huseyin Demirbilek,Khalid Hussain
Pratik Shah
Persistent hyperinsulinaemic hypoglycaemia in infancy (PHHI) is a heterogeneous condition characterised by unregulated insulin secretion in response to a low blood glucose level. It is the most common cause of severe and persistent hypoglyc...
Radu Mihai
Radu Mihai
Apart from neuroblastomas, adrenal tumors are exceedingly rare in children and young adults. In this age group, the vast majority of patients present with clinical signs associated with excess hormone production. The most common tumor to ar...
Jocelyn F Burke,Herbert Chen,Ankush Gosain
Jocelyn F Burke
This review of parathyroid surgery in children will briefly discuss parathyroid gland embryology and anatomy before focusing on the pathophysiology, clinical presentation, and treatment of hyperparathyroidism in children. Hyperparathyroidis...