Corrigendum to "Depletion of NAD pool contributes to impairment of endothelial progenitor cell mobilization in diabetes" [Metab Clin Exp 65 (2016) 852-862] [0.03%]
关于“糖尿病中NAD池的耗竭导致内皮祖细胞动员能力受损”的勘误[代谢临床实验第65卷（2016）852-862页]
Pei Wang,Xi Yang,Zheng Zhang et al.
Pei Wang et al.
Obeticholic acid for the treatment of nonalcoholic steatohepatitis: Expectations and concerns [0.03%]
奥贝胆酸治疗非酒精性脂肪肝病：期待与顾虑
Stergios A Polyzos,Jannis Kountouras,Christos S Mantzoros
Stergios A Polyzos
Metabolic flexibility is impaired in women who are pregnant and overweight/obese and related to insulin resistance and inflammation [0.03%]
代谢灵活性的受损与妊娠期超重或肥胖有关，并且与胰岛素抵抗和炎症相关
Rachel A Tinius,Maire M Blankenship,Karen E Furgal et al.
Rachel A Tinius et al.
Context: Maternal obesity is a significant public health concern that contributes to unfavorable outcomes such as inflammation and insulin resistance. Women with obesity may have impaired metabolic flexibility (i.e. an in...
Far-infrared radiation prevents decline in β-cell mass and function in diabetic mice via the mitochondria-mediated Sirtuin1 pathway [0.03%]
远红外辐照可通过线粒体介导的Sirtuin1通路防止糖尿病小鼠β细胞质量和功能的下降
Yung-Ho Hsu,Yen-Cheng Chen,Yu-Wei Chen et al.
Yung-Ho Hsu et al.
Insulin deficiency in type 2 diabetes mellitus (DM) involves a decline in both pancreatic β-cell mass and function. Enhancing β-cell preservation represents an important therapeutic strategy to treat type 2 DM. Far-infrared (FIR) radiatio...
Epigenetic silencing of microRNA-125b-5p promotes liver fibrosis in nonalcoholic fatty liver disease via integrin α8-mediated activation of RhoA signaling pathway [0.03%]
表观遗传沉默的microRNA-125b-5p通过整合素α8介导的RhoA信号途径促进非酒精性脂肪肝病肝纤维化
Qingxian Cai,Fengjuan Chen,Fen Xu et al.
Qingxian Cai et al.
Background: Nonalcoholic fatty liver disease (NAFLD) is one of the most common chronic liver diseases that may progress to liver fibrosis or cancer. The present study aimed to investigate the role of microRNA-125b-5p (miR...
High-density lipoprotein cholesterol efflux capacity and cardiovascular risk in autoimmune and non-autoimmune diseases [0.03%]
自身免疫性和非自身免疫性疾病中的高密度脂蛋白胆固醇外流能力与心血管风险的关系
Anouar Hafiane,Elda Favari,Stella S Daskalopoulou et al.
Anouar Hafiane et al.
Functional assessment of cholesterol efflux capacity (CEC) to high-density lipoprotein (HDL) is an emerging tool for evaluating morbidity and mortality associated with cardiovascular disease (CVD). By promoting macrophage reverse cholestero...
Time trends and predictors of hypovitaminosis D across the life course: 2009-2016 [0.03%]
2009～2016年生命历程中维生素D缺乏的时间趋势及其预测因素
Randa K Saad,Vanessa C Akiki,Maya Rahme et al.
Randa K Saad et al.
Purpose: We investigated prevalence, determinants, seasonal changes, and time trends in hypovitaminosis D. We derived a desirable serum 25-hydroxy-vitamin D (25OHD) level in adults/elderly by evaluating the 25OHD-parathyr...
Time for a paradigm shift in treating type 1 diabetes mellitus: coupling inflammation to islet regeneration [0.03%]
治疗1型糖尿病的时代呼唤：从抗炎到胰岛再生转换的新范式
Nadia Cobo-Vuilleumier,Benoit R Gauthier
Nadia Cobo-Vuilleumier
Type 1 diabetes mellitus (T1DM) is an autoimmune disease that targets the destruction of islet beta-cells resulting in insulin deficiency, hyperglycemia and death if untreated. Despite advances in medical devices and longer-acting insulin, ...
The combination of linagliptin, metformin and lifestyle modification to prevent type 2 diabetes (PRELLIM). A randomized clinical trial [0.03%]
利格列汀、二甲双胍和生活方式改变联合使用预防2型糖尿病（PRELLIM）试验
Rodolfo Guardado-Mendoza,Sara Stephania Salazar-López,Mildred Álvarez-Canales et al.
Rodolfo Guardado-Mendoza et al.
Background: Prediabetes is a highly prevalent health problem with a high risk of complications and progression to type 2 diabetes (T2D). The goals of this study were to evaluate the effect of the combination of lingalipti...
Randomized Controlled Trial
Metabolism: clinical and experimental. 2020 Mar:104:154054. DOI:10.1016/j.metabol.2019.154054 2020
High-resolution metabolomics study revealing l-homocysteine sulfinic acid, cysteic acid, and carnitine as novel biomarkers for high acute myocardial infarction risk [0.03%]
高分辨率代谢组学研究揭示了L型同型半胱氨酸磺酸、胱氨酸和肉碱是高急性心肌梗死风险的新生物标志物
Adnan Khan,Yoonjeong Choi,Joung Hwan Back et al.
Adnan Khan et al.
Background: Identifying changes in serum metabolites before the occurrence of acute myocardial infarction (AMI) is an important approach for finding novel biomarkers of AMI. ...