FNDC4, a novel adipokine that reduces lipogenesis and promotes fat browning in human visceral adipocytes [0.03%]
FNDC4：一种减少脂肪生成并促进人类内脏脂肪细胞褐色化的新型脂肪因子
Gema Frühbeck,Blanca Fernández-Quintana,Mirla Paniagua et al.
Gema Frühbeck et al.
Background: Fibronectin type IIIdomain-containing protein 4 (FNDC4) constitutes a secreted factor showing a high homology in the fibronectin type III and transmembrane domains with the exercise-associated myokine irisin (...
Advances in non-invasive biomarkers for the diagnosis and monitoring of non-alcoholic fatty liver disease [0.03%]
非酒精性脂肪性肝病诊断与监测的无创标志物进展
Michelle T Long,Sanil Gandhi,Rohit Loomba
Michelle T Long
Non-alcoholic fatty liver disease (NAFLD) is now the most common chronic liver disease in the United States, affecting approximately 1 out of every 4 Americans. NAFLD is a spectrum of disorders including simple steatosis, characterized by t...
Targeting mammalian serine/threonine-protein kinase 4 through Yes-associated protein/TEA domain transcription factor-mediated epithelial-mesenchymal transition ameliorates diabetic nephropathy orchestrated renal fibrosis [0.03%]
靶向丝裂原活化蛋白激酶4通过Yes相关蛋白/TEA转录因子介导的上皮间质转化缓解糖尿病肾病orchestrated肾纤维化
Tingting Yang,Cai Heng,Yi Zhou et al.
Tingting Yang et al.
Rationale: Tubulointerstitial fibrosis, which is closely related to functional injury of the kidney, can be observed in advanced stages of diabetic nephropathy (DN). Mammalian serine/threonine-protein kinase 4 (MST1), a c...
Increased AMP deaminase activity decreases ATP content and slows protein degradation in cultured skeletal muscle [0.03%]
AMP脱氨酶活性增加降低了培养骨骼肌中的ATP含量并减慢蛋白质降解速度
Patrick R Davis,Spencer G Miller,Nicolas A Verhoeven et al.
Patrick R Davis et al.
Background: Protein degradation is an energy-dependent process, requiring ATP at multiple steps. However, reports conflict as to the relationship between intracellular energetics and the rate of proteasome-mediated protei...
Letter to the Editor: The first Ramadan during COVID-19 pandemic: 1.8 billion Muslims should fast or not? [0.03%]
读者来信：新冠肺炎疫情之下的第一个斋月：全世界18亿穆斯林要不要封斋？
Saeedeh Mosaferchi,Ehsan Sharif-Paghaleh,Alireza Mortezapour et al.
Saeedeh Mosaferchi et al.
Letter to the Editor: Obesity as a risk factor for greater severity of COVID-19 in patients with metabolic associated fatty liver disease [0.03%]
读者来信：肥胖会增加代谢相关性脂肪性肝病患者的COVID-19重症风险
Abdulzahra Hussain,Peter Vasas,Shamsi El-Hasani
Abdulzahra Hussain
Letter to the Editor: Fasting plasma glucose associated with mortality rate in T2DM patients with COVID-19 infection [0.03%]
读者来信：糖尿病患者血糖与新冠肺炎死亡率的关系
Wen Kong,Jiaoyue Zhang,Ying Xu et al.
Wen Kong et al.
Giovanna Muscogiuri,Gabriella Pugliese,Luigi Barrea et al.
Giovanna Muscogiuri et al.
Commentary: Testosterone, a key hormone in the context of COVID-19 pandemic [0.03%]
评论：测试睾丸激素在新冠肺炎大流行背景下的关键作用
Paolo Pozzilli,Andrea Lenzi
Paolo Pozzilli