Flot2 protects against podocyte injury by maintaining the stability of synaptopodin in diabetic nephropathy [0.03%]
Flot2通过维持糖尿病肾病中synaptopodin的稳定性来保护足细胞免受损伤
Hong Zhang,Wenbiao Wang,Peimin Liu et al.
Hong Zhang et al.
Podocyte injury is a major determinant of diabetic nephropathy (DN). Critical structural proteins such as synaptopodin play an important role in maintaining podocyte morphology and function. Herein, we uncover a protective role of Flotillin...
Time for a change? Threshold for obesity in contemporary Japanese population [0.03%]
japanese成人肥胖标准再检讨
Kenya Kasahara,Yodai Ichikawa,Junya Hironaka et al.
Kenya Kasahara et al.
Background: The obesity criteria for Japanese population are defined based on a cross-sectional study conducted 30 years ago. We aimed to examine the validity of a BMI of 25 kg/m2 as a determinant of obesity in the Japane...
Metabolic regulation of tissue-resident immune cells: Molecular mechanisms and therapeutic implications [0.03%]
组织驻留免疫细胞的代谢调控：分子机制和治疗意义
Zixiang Chen,Fan Xiao,Xiaoxia Zhu et al.
Zixiang Chen et al.
Many innate and adaptive immune cells are resident in non-lymphoid tissues and do not participate in peripheral circulation. These tissue-resident immune cells not only rapidly recognize and respond to local infections or injuries but also ...
Corrigendum to "Exosomal miRNAs in muscle-bone crosstalk: Mechanistic links, exercise modulation and implications for sarcopenia, osteoporosis and osteosarcopenia" [metabolism. 2025 Jun 21:156333] [0.03%]
关于“肌肉-骨骼交叉对话中的外泌体miRNA：机制联系、运动调节及肌少症、骨质疏松和肌骨减少症的启示”的勘误 [ metabolism. 2025年6月21日:156333]
Bo Zhang,Yang Chen,Qiaojie Chen et al.
Bo Zhang et al.
AEBP1 as a promising therapeutic target for skeletal muscle insulin resistance in type 2 diabetes mellitus: Convergent evidence from Mendelian randomization and functional validation [0.03%]
基于孟德尔随机化和功能验证的AEBP1作为2型糖尿病骨骼肌胰岛素抵抗治疗靶点的证据
Chen Guo,Jiani Li,Xiaofei Yang et al.
Chen Guo et al.
Background: The pathogenesis of type 2 diabetes mellitus (T2DM) is closely related to skeletal muscle insulin resistance (IR). Currently, there is still a lack of relevant treatments. Summary-data-based Mendelian randomiz...
MASLD may influence female-specific cancer risk indirectly through shared metabolic pathways rather than direct causation - author's reply [0.03%]
MASLD可能通过与性别特定癌症的共享代谢途径间接影响女性患癌风险，而非直接因果关系——作者回复
Xinrong Zhang,Mindie H Nguyen
Xinrong Zhang
Response to "expanding the clinical and Immunogenomic relevance of SAMD1 in hepatocellular carcinoma" [0.03%]
“SAMD1在肝细胞癌的临床和免疫基因组学中的作用及对相关研究的回应”
Guo-Qiang Pan,Yu-Chuan Yan,Rui-Zhe Li et al.
Guo-Qiang Pan et al.
Carboxylic acid metabolism in cancer: Mechanisms, microenvironment interactions, and therapeutic opportunities [0.03%]
癌症中的羧酸代谢：机制、微环境相互作用及治疗机会
Xiqing Bian,Yue Zhuo,Luo Zhou et al.
Xiqing Bian et al.
Cancer cells reprogram their metabolism to favor aerobic glycolysis and enhance carboxylic acid metabolism, supporting their energy needs and promoting tumor progression. This review explores the role of carboxylic acids, such as lactate, f...
Hongyi Chen,Yuying Ma,Qiang Wang
Hongyi Chen