Implications of the dynamic nature of metabolic health status and obesity on risk of incident cardiovascular events and mortality: a nationwide population-based cohort study [0.03%]
代谢健康状况和肥胖的动态变化对心血管事件和死亡风险的影响：全国基于人群的队列研究
Yun Kyung Cho,Yu Mi Kang,Jee Hee Yoo et al.
Yun Kyung Cho et al.
Aims: We hypothesized that transitions in metabolic health status and obesity affect the cardiovascular (CV) risk and mortality in population with metabolically healthy obesity (MHO). ...
Association between Helicobacter pylori infection and risk of nonalcoholic fatty liver disease: An updated meta-analysis [0.03%]
幽门螺杆菌感染与非酒精性脂肪肝病发病风险的关联：一项更新的meta分析研究
Alessandro Mantovani,Teresa Turino,Anna Altomari et al.
Alessandro Mantovani et al.
Background: Recent studies that have examined the association between Helicobacter pylori infection and risk of nonalcoholic fatty liver disease (NAFLD) have produced conflicting data. We have performed a systematic revie...
Jens Juul Holst
Jens Juul Holst
The incretin effect, the amplification of insulin secretion occurring when glucose is taken in orally as compared to infused intravenously, is one of the factors that help the body to tolerate carbohydrate/glucose ingestion. These include 1...
YY1: A novel therapeutic target for diabetic nephropathy orchestrated renal fibrosis [0.03%]
YY1：一种新的糖尿病肾病诱导肾纤维化的治疗靶点
Tingting Yang,Fanglin Shu,Hao Yang et al.
Tingting Yang et al.
Background: Renal fibrosis promotes the development of diabetic nephropathy (DN). A growing number of studies have reported that Yin Yang 1 (YY1), which is involved in cellular proliferation and differentiation, plays a c...
Corrigendum to "The BACE1 product sAPPβ induces ER stress and inflammation and impairs insulin signaling" [Metab Clin Exp 85 (2018) 59-75] [0.03%]
“BACE1产物sAPPβ导致内质网应激及炎症并损害胰岛素信号——代号为METAB CLR C&E的元数据更正（META-COR）”[代谢临床实验第85期（2018）59-75]
Gaia Botteri,Laia Salvadó,Anna Gumà et al.
Gaia Botteri et al.
Lipoxygenase drives lipidomic and metabolic reprogramming in ischemic heart failure [0.03%]
脂氧合酶驱动的缺血性心力衰竭中的脂质组和代谢重组
Ganesh V Halade,Vasundhara Kain,Bochra Tourki et al.
Ganesh V Halade et al.
Background: After myocardial infarction (MI), delayed progression or reversal of cardiac remodeling is a prime target to limit advanced chronic heart failure (HF). However, the temporal kinetics of lipidomic and systemic ...
Fatty acid binding protein 4 (FABP4) as a potential biomarker reflecting myocardial lipid storage in type 2 diabetes [0.03%]
游离脂肪酸结合蛋白4(FABP4)可作为反映2型糖尿病患者心肌脂质蓄积的生物标志物
Ricardo Rodríguez-Calvo,Josefa Girona,Marina Rodríguez et al.
Ricardo Rodríguez-Calvo et al.
Objective: Fatty acid binding protein 4 (FABP4) is an intracellular lipid chaperone involved in the crosstalk between adipose and peripheral tissues, and it contributes to widespread insulin resistance in cells, including...
Fractional turnover of apolipoprotein(a) and apolipoprotein B-100 within plasma lipoprotein(a) particles in statin-treated patients with elevated and normal Lp(a) concentration [0.03%]
他汀治疗患者的升高的和正常的Lp（a）浓度的血浆Lp（a）颗粒中载脂蛋白（a）和载脂蛋白B-100的周转率
Louis Ma,Dick C Chan,Esther M M Ooi et al.
Louis Ma et al.
Context: Lipoprotein(a) [Lp(a)] is a highly atherogenic lipoprotein characterized by apolipoprotein(a) [apo(a)] covalently bounded to apoB-100 (apoB). However, the metabolism of apo(a) and apoB within plasma Lp(a) particl...
Sodium-glucose co-transporter-2 inhibitors (SGLT2i) use and risk of amputation: an expert panel overview of the evidence [0.03%]
钠葡萄糖协同转运蛋白-2抑制剂(SGLT2i)的使用与截肢风险：证据概览专家意见小组审议报告
Niki Katsiki,George Dimitriadis,George Hahalis et al.
Niki Katsiki et al.
Sodium-glucose co-transporter-2 inhibitors (SGLT2i) are oral antidiabetic agents that exert their glucose-lowering effect by increasing renal excretion of glucose. These drugs have been reported to beneficially affect cardiovascular (CV) an...
FoxO1 localizes to mitochondria of adipose tissue and is affected by nutrient stress [0.03%]
FOXO1定位于脂肪组织的线粒体并受营养压力影响
Daniele Lettieri-Barbato,Laura Ioannilli,Katia Aquilano et al.
Daniele Lettieri-Barbato et al.
Objective: Mitochondria play pivotal roles in orchestrating signaling pathways in order to guarantee metabolic homeostasis under different stimuli. It has been demonstrated that the mito-nuclear communication is fundament...