Severe Eosinophilic Gastritis is Associated with Peripheral Eosinophilia and Multi-Organ Involvement [0.03%]
重度嗜酸细胞性胃炎与外周嗜酸性粒细胞增多和多器官受累有关
Xintong Wang,Yansheng Hao,Hansen Lam et al.
Xintong Wang et al.
Histologic gastric eosinophilia (HGE), characterized by dense eosinophil infiltration in gastric mucosa, is an understudied disease with unclear etiology. Unlike its counterpart, eosinophilic esophagitis (EoE), which has defined diagnostic ...
Assessment of Nectin4-Expression in Vulvar Squamous Cell Carcinomas (VSCC): correlation with HPV-associated and HPV-independent Molecular Subtypes [0.03%]
评估外阴鳞状细胞癌(VSCC)中nectin4的表达：与HPV相关和非HPV独立分子亚型的相关性
Anne Kathrin Höhn,Grit Gesine Ruth Hiller,Benjamin Wolf et al.
Anne Kathrin Höhn et al.
Background: The development of antibody-drug conjugates (ADC) for cancer treatment has achieved promising results in different solid tumors and targets. Enfortumab-Vedotin (EV), a humanised anti-Nectin4-IgG1 monoclonal an...
Impact of Neoadjuvant Chemotherapy on PD-L1 Expression in Oral Squamous Cell Carcinoma: A Matched Biopsy-Resection Study [0.03%]
新辅助化疗对口腔鳞癌PD-L1表达影响的配对活检研究
Deeksha Agrawal,Nidhi Anand,Nuzhat Husain et al.
Deeksha Agrawal et al.
Background: Programmed death ligand 1 (PD-L1) is essential for immune evasion and serves as a significant biomarker for immunotherapy in oral squamous cell carcinoma (OSCC). Nevertheless, the changes in its expression aft...
High-Grade Endometrioid Carcinomas With Pilomatrix-like Features lacking CTNNB1 Mutations: Clinicopathologic Characteristics and Novel Molecular Events [0.03%]
具有斑秃样特征且缺乏CTNNB1基因突变的高级别子宫内膜样癌的临床病理特点及分子新事件
Lei Qin,Wanrun Lin,Suming Huang et al.
Lei Qin et al.
Context: Pilomatrix-like high-grade endometrioid carcinoma (PiMHEC) represents a recently described, aggressive variant of endometrial carcinoma. Prior reports have linked PiMHEC with CTNNB1 exon 3 mutations and abnormal ...
Idiopathic Cholestasis in Adults: Genetics as another Lens for Liver Pathologists [0.03%]
成人原发性胆汁性肝硬化：遗传学在病理学中的另一视角
Cecelia Tamburro,Anne Mentzinger,Dhanpat Jain et al.
Cecelia Tamburro et al.
Chronic liver disease (CLD) is a significant global health problem, responsible for approximately two million deaths annually. Despite extensive diagnostic evaluations, a proportion of patients with CLD remain undiagnosed, making the study ...
A real-world study on the expression and clinical application of IMP3 immunohistochemistry in bone tumors [0.03%]
骨肿瘤中IMP3免疫组化表达及临床应用价值的初步研究
Qingzhu Wei,Lin Zhong,Hui Zhou et al.
Qingzhu Wei et al.
Previous studies have confirmed that insulin-like growth factor 2 mRNA-binding protein 3 (IMP3) is widely expressed in various malignant tumors. However, no systematic study has assessed the expression of IMP3 in bone tumors. We immunohisto...
Eosinophil-rich Esophagitis Pattern in Patients with Allogenic Hematopoietic Stem Cell Transplantation: a multicenter experience [0.03%]
异基因造血干细胞移植患者中富含嗜酸性粒细胞的食管炎型模式：多中心经验
Reem Youssef,Kwun Wah Wen,Zahra Alipour et al.
Reem Youssef et al.
Eosinophil-rich esophagitis is a pattern of inflammation characterized by increased intraepithelial eosinophils which is associated with a wide range of disorders including eosinophilic esophagitis (EoE). In hematopoietic stem cell transpla...
Continuous cast-like intrabiliary extension of biliary neoplasm associated with mass-forming invasive carcinoma may be a hitherto poorly-described progression of intraductal tubulopapillary neoplasm of the bile duct [0.03%]
类似连续铸型的胆管内肝外胆道肿瘤与团块型浸润癌的关联可能是尚未充分描述的胆管原位管状乳头状新生物的进展形式
Yasuni Nakanuma,Yuko Kakuda,Hiroyuki Matsubayashi et al.
Yasuni Nakanuma et al.
Intracranial low-grade tumors with ALK rearrangement: diverse tumor types with shared molecular alterations [0.03%]
低级别ALK重排颅内肿瘤：不同类型的肿瘤具有相同的分子改变
Kun Mu,Yu Zhang,Yuyu Yang et al.
Kun Mu et al.
Although anaplastic lymphoma kinase (ALK) gene fusions are increasingly recognized in newly classified pediatric high-grade gliomas, intracranial low-grade tumors harboring ALK rearrangements remain under characterized in the literature. He...
Fluorescence in situ Hybridization (FISH)-Based Detection of Paracentric Inversions Leading to RBM10::TFE3 Rearrangement [0.03%]
基于荧光原位杂交(FISH)技术检测导致RBM10::TFE3重排的并联倒位事件
Sounak Gupta,Daniel R Sill,Loren P Herrera Hernandez et al.
Sounak Gupta et al.